node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK71201.1 | ABK72323.1 | MSMEG_4256 | MSMEG_6935 | Identified by match to protein family HMM PF00877. | N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01471; match to protein family HMM PF01520. | 0.434 |
ABK71862.1 | ABK72323.1 | MSMEG_1679 | MSMEG_6935 | AmiB; Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; Belongs to the peptidase M20A family. | N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01471; match to protein family HMM PF01520. | 0.615 |
ABK71862.1 | dapD | MSMEG_1679 | MSMEG_5104 | AmiB; Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; Belongs to the peptidase M20A family. | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.542 |
ABK72323.1 | ABK71201.1 | MSMEG_6935 | MSMEG_4256 | N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01471; match to protein family HMM PF01520. | Identified by match to protein family HMM PF00877. | 0.434 |
ABK72323.1 | ABK71862.1 | MSMEG_6935 | MSMEG_1679 | N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01471; match to protein family HMM PF01520. | AmiB; Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; Belongs to the peptidase M20A family. | 0.615 |
ABK72323.1 | ABK72792.1 | MSMEG_6935 | MSMEG_5315 | N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01471; match to protein family HMM PF01520. | Gp35 protein; Identified by match to protein family HMM PF01471; match to protein family HMM PF01510. | 0.896 |
ABK72323.1 | ABK73137.1 | MSMEG_6935 | MSMEG_4643 | N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01471; match to protein family HMM PF01520. | Resuscitation-promoting factor; Identified by match to protein family HMM PF06737. | 0.568 |
ABK72323.1 | murA | MSMEG_6935 | MSMEG_4932 | N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01471; match to protein family HMM PF01520. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.870 |
ABK72323.1 | pknB | MSMEG_6935 | MSMEG_0028 | N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01471; match to protein family HMM PF01520. | Serine-threonine protein kinase; Protein kinase that regulates many aspects of mycobacterial physiology. Is a key component of a signal transduction pathway that regulates cell growth, cell shape and cell division via phosphorylation of target proteins (By similarity). Probably phosphorylates RseA. | 0.495 |
ABK72323.1 | ponA1 | MSMEG_6935 | MSMEG_6900 | N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01471; match to protein family HMM PF01520. | Penicillin-binding protein 1; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits) (By similarity). | 0.449 |
ABK72323.1 | ripA | MSMEG_6935 | MSMEG_3145 | N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01471; match to protein family HMM PF01520. | Secreted cell wall-associated hydrolase; Peptidoglycan endopeptidase that cleaves the bond between D- glutamate and meso-diaminopimelate. Binds and degrades high-molecular weight peptidoglycan. Required for normal separation of daughter cells after cell division and for cell wall integrity (By similarity). | 0.435 |
ABK72792.1 | ABK72323.1 | MSMEG_5315 | MSMEG_6935 | Gp35 protein; Identified by match to protein family HMM PF01471; match to protein family HMM PF01510. | N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01471; match to protein family HMM PF01520. | 0.896 |
ABK73137.1 | ABK72323.1 | MSMEG_4643 | MSMEG_6935 | Resuscitation-promoting factor; Identified by match to protein family HMM PF06737. | N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01471; match to protein family HMM PF01520. | 0.568 |
ABK73137.1 | pknB | MSMEG_4643 | MSMEG_0028 | Resuscitation-promoting factor; Identified by match to protein family HMM PF06737. | Serine-threonine protein kinase; Protein kinase that regulates many aspects of mycobacterial physiology. Is a key component of a signal transduction pathway that regulates cell growth, cell shape and cell division via phosphorylation of target proteins (By similarity). Probably phosphorylates RseA. | 0.437 |
ABK73137.1 | ponA1 | MSMEG_4643 | MSMEG_6900 | Resuscitation-promoting factor; Identified by match to protein family HMM PF06737. | Penicillin-binding protein 1; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits) (By similarity). | 0.544 |
ABK73137.1 | ripA | MSMEG_4643 | MSMEG_3145 | Resuscitation-promoting factor; Identified by match to protein family HMM PF06737. | Secreted cell wall-associated hydrolase; Peptidoglycan endopeptidase that cleaves the bond between D- glutamate and meso-diaminopimelate. Binds and degrades high-molecular weight peptidoglycan. Required for normal separation of daughter cells after cell division and for cell wall integrity (By similarity). | 0.914 |
dapD | ABK71862.1 | MSMEG_5104 | MSMEG_1679 | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | AmiB; Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; Belongs to the peptidase M20A family. | 0.542 |
dapD | ftsZ | MSMEG_5104 | MSMEG_4222 | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.498 |
dapD | murA | MSMEG_5104 | MSMEG_4932 | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.747 |
ftsZ | dapD | MSMEG_4222 | MSMEG_5104 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.498 |