Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABK70862.1 | fbpB | MSMEG_3662 | MSMEG_2078 | Mannose-binding lectin; Identified by match to protein family HMM PF01453; match to protein family HMM PF01476. | Antigen 85-C; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein. They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (By similarity). | 0.571 |
| ABK70862.1 | glgB | MSMEG_3662 | MSMEG_4918 | Mannose-binding lectin; Identified by match to protein family HMM PF01453; match to protein family HMM PF01476. | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. | 0.613 |
| ABK70862.1 | glgC | MSMEG_3662 | MSMEG_5078 | Mannose-binding lectin; Identified by match to protein family HMM PF01453; match to protein family HMM PF01476. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. | 0.760 |
| ABK70862.1 | glgE | MSMEG_3662 | MSMEG_4916 | Mannose-binding lectin; Identified by match to protein family HMM PF01453; match to protein family HMM PF01476. | Alpha-amylase family protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is also able to catalyze the reverse reaction in vitro. Cannot use glucose 1-phosphate as substrate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. | 0.618 |
| ABK70862.1 | lprG | MSMEG_3662 | MSMEG_3070 | Mannose-binding lectin; Identified by match to protein family HMM PF01453; match to protein family HMM PF01476. | LprG protein; Probably helps membrane protein MSMEG_3069/MSMEI_2992 (P55) transport triacylglycerides (TAG) across the inner cell membrane into the periplasm and probably ultimately to the outer membrane (By similarity). Required for MSMEG_3069/MSMEI_2992 export activity. Export of ethidium bromide by MSMEG_3069/MSMEI_2992 can be complemented by the equivalent operon from M.tuberculosis (lprG-Rv1410c). Belongs to the LppX/LprAFG lipoprotein family. | 0.405 |
| ABK70862.1 | mak | MSMEG_3662 | MSMEG_6514 | Mannose-binding lectin; Identified by match to protein family HMM PF01453; match to protein family HMM PF01476. | Trehalose synthase-fused probable maltokinase; Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate (Probable). Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB. | 0.754 |
| ABK70862.1 | otsA | MSMEG_3662 | MSMEG_5892 | Mannose-binding lectin; Identified by match to protein family HMM PF01453; match to protein family HMM PF01476. | Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Involved in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1- phosphate (M1P), and probably in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to glucose-6-phosphate (Glc-6-P) to form trehalose-6-phosphate. ADP-Glc, CDP-Glc, GDP- Glc and TDP-Glc are also glucosyl donors, however, when the pyrimidine sugar nucleotides (CDP-Glc, TDP-Glc and UDP-Glc) are used as substrates, there is an absolute requirement [...] | 0.425 |
| ABK70862.1 | otsB | MSMEG_3662 | MSMEG_6043 | Mannose-binding lectin; Identified by match to protein family HMM PF01453; match to protein family HMM PF01476. | Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. | 0.412 |
| ABK72491.1 | glgB | MSMEG_4915 | MSMEG_4918 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. | 0.998 |
| ABK72491.1 | glgC | MSMEG_4915 | MSMEG_5078 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. | 0.996 |
| ABK72491.1 | glgE | MSMEG_4915 | MSMEG_4916 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | Alpha-amylase family protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is also able to catalyze the reverse reaction in vitro. Cannot use glucose 1-phosphate as substrate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. | 0.964 |
| ABK72491.1 | glgM | MSMEG_4915 | MSMEG_5080 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | Glycogen synthase; Involved in the biosynthesis of the maltose-1-phosphate (M1P) building block required for alpha-glucan production by the key enzyme GlgE. Catalyzes the formation of an alpha-1,4 linkage between glucose from ADP-glucose and glucose 1-phosphate (G1P) to yield maltose-1- phosphate (M1P). | 0.990 |
| ABK72491.1 | glgX | MSMEG_4915 | MSMEG_3186 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | Glycogen debranching enzyme GlgX; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02100; Belongs to the glycosyl hydrolase 13 family. | 0.994 |
| ABK72491.1 | glgX-2 | MSMEG_4915 | MSMEG_6507 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | Glycogen debranching enzyme GlgX; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02100; Belongs to the glycosyl hydrolase 13 family. | 0.983 |
| ABK72491.1 | gpgS | MSMEG_4915 | MSMEG_5084 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | Glycosyl transferase, group 2 family protein; Involved in the biosynthesis of 6-O-methylglucose lipopolysaccarides (MGLPs). Catalyzes the transfer of a glucose (Glc) moiety from uridine diphosphate (UDP-Glc) to the position 2 of 3-phospho-D-glycerate (3- PGA) to form glucosyl-3-phosphoglycerate (GPG). It can use UDP-glucose, ADP-glucose and GDP-glucose as donor substrates with decreasing affinity, and 3-PGA as an acceptor. D-glycerate could only be the acceptor with ADP- glucose and at a very low rate. | 0.628 |
| ABK72491.1 | mak | MSMEG_4915 | MSMEG_6514 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | Trehalose synthase-fused probable maltokinase; Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate (Probable). Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB. | 0.871 |
| ABK72491.1 | otsA | MSMEG_4915 | MSMEG_5892 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Involved in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1- phosphate (M1P), and probably in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to glucose-6-phosphate (Glc-6-P) to form trehalose-6-phosphate. ADP-Glc, CDP-Glc, GDP- Glc and TDP-Glc are also glucosyl donors, however, when the pyrimidine sugar nucleotides (CDP-Glc, TDP-Glc and UDP-Glc) are used as substrates, there is an absolute requirement [...] | 0.640 |
| ABK72491.1 | otsB | MSMEG_4915 | MSMEG_6043 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. | 0.679 |
| ABK72491.1 | treZ | MSMEG_4915 | MSMEG_3184 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | Malto-oligosyltrehalose trehalohydrolase; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402. | 0.889 |
| aftC | fbpB | MSMEG_2785 | MSMEG_2078 | Putative conserved integral membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG. | Antigen 85-C; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein. They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (By similarity). | 0.708 |
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