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ABK69785.1 ABK69785.1 pckG pckG ABK72728.1 ABK72728.1 sodC sodC aceA aceA ureC ureC ABK72648.1 ABK72648.1 ABK75969.1 ABK75969.1 ABK71796.1 ABK71796.1 metK metK ABK74374.1 ABK74374.1 ABK76129.1 ABK76129.1 katG katG ureC-2 ureC-2 aceA-2 aceA-2 katG-2 katG-2 ABK70439.1 ABK70439.1 gdh gdh ahpD ahpD glgB glgB ABK73098.1 ABK73098.1 gabD2 gabD2 ABK71113.1 ABK71113.1 katG-3 katG-3 sodA sodA ABK75878.1 ABK75878.1 treS treS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABK69785.1[NADP+] succinate-semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171. (460 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (608 aa)
ABK72728.1Succinic semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (484 aa)
sodCCopper/zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (236 aa)
aceAIsocitrate lyase; Identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346. (428 aa)
ureCUrease, alpha subunit; Identified by match to protein family HMM PF00449; match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01792. (568 aa)
ABK72648.1[NADP+] succinate-semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (486 aa)
ABK75969.1Identified by match to protein family HMM PF01230. (205 aa)
ABK71796.1Succinate-semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171. (501 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (399 aa)
ABK74374.1L-asparaginase; Identified by match to protein family HMM PF00710. (320 aa)
ABK76129.1Succinate semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171. (450 aa)
katGCatalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. May play a role in the intracellular survival of mycobacteria. (748 aa)
ureC-2Urease, alpha subunit; Identified by match to protein family HMM PF00449; match to protein family HMM PF01979; match to protein family HMM TIGR01792; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (577 aa)
aceA-2Isocitrate lyase; Identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346. (769 aa)
katG-2Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (688 aa)
ABK70439.1Cytosine deaminase; Identified by match to protein family HMM PF00383. (146 aa)
gdhNAD-glutamate dehydrogenase; Catalyzes the reversible conversion of L-glutamate to 2- oxoglutarate. Highly specific for NAD. (1594 aa)
ahpDAlkylhydroperoxidase, AhpD family protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. (177 aa)
glgB1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. (736 aa)
ABK73098.1[NADP+] succinate-semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (482 aa)
gabD2Succinic semialdehyde dehydrogenase; Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate. Although it has succinate semialdehyde dehydrogenase activity, is likely to act physiologically on a different aldehyde(s) (By similarity). (517 aa)
ABK71113.1Aspartate transaminase; Identified by match to protein family HMM PF00155. (428 aa)
katG-3Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. May play a role in the intracellular survival of mycobacteria. (739 aa)
sodA[Mn] superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (207 aa)
ABK75878.1[NADP+] succinate-semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171. (450 aa)
treSTrehalose synthase; Catalyzes the reversible interconversion of maltose and trehalose by transglucosylation. Maltose is the preferred substrate. To a lesser extent, also displays amylase activity, catalyzing the endohydrolysis of (1->4)-alpha-D- glucosidic linkages in glycogen and maltooligosaccharides such as maltoheptaose, to produce maltose which then can be converted to trehalose. TreS plays a key role in the utilization of trehalose for the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P). Might also functio [...] (593 aa)
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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