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katG katG ABK70552.1 ABK70552.1 nuoG nuoG ABK72021.1 ABK72021.1 secA secA ABK75495.1 ABK75495.1 ABK72366.1 ABK72366.1 rplM rplM ABK71940.1 ABK71940.1 sodC sodC glnA-3 glnA-3 ABK69912.1 ABK69912.1 ABK76235.1 ABK76235.1 ABK75399.1 ABK75399.1 phoP phoP glnT glnT katG-3 katG-3 sodA sodA katG-2 katG-2 ABK75823.1 ABK75823.1 ABK70330.1 ABK70330.1 glnA-2 glnA-2 secA2 secA2 garA garA glnA glnA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
katGCatalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. May play a role in the intracellular survival of mycobacteria. (748 aa)
ABK70552.1Gamma-glutamylisopropylamide synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (457 aa)
nuoGNADH-quinone oxidoreductase, G subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (794 aa)
ABK72021.1Identified by match to protein family HMM PF00300. (203 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (953 aa)
ABK75495.1Rubredoxin; Identified by match to protein family HMM PF00301. (60 aa)
ABK72366.1Rubredoxin; Identified by match to protein family HMM PF00301; Belongs to the rubredoxin family. (57 aa)
rplMRibosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (147 aa)
ABK71940.1Gamma-glutamylisopropylamide synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (450 aa)
sodCCopper/zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (236 aa)
glnA-3Glutamine synthetase, type I; Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback- inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation [...] (446 aa)
ABK69912.1Phosphoglycerate mutase; Identified by match to protein family HMM PF00300. (365 aa)
ABK76235.1Glutamate--ammonia ligase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (477 aa)
ABK75399.1Glutamine synthetase III; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (461 aa)
phoPDNA-binding response regulator PhoP; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. (239 aa)
glnTGlutamine synthetase, type III; Identified by match to protein family HMM PF00120; match to protein family HMM TIGR03105; Belongs to the glutamine synthetase family. (434 aa)
katG-3Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. May play a role in the intracellular survival of mycobacteria. (739 aa)
sodA[Mn] superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (207 aa)
katG-2Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (688 aa)
ABK75823.1Glutamine synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (430 aa)
ABK70330.1Glutamine synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (459 aa)
glnA-2Glutamine synthetase, type I; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. (478 aa)
secA2ATPase SecA2; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (784 aa)
garAForkhead-associated protein; Involved in regulation of glutamate metabolism. Acts as a phosphorylation-dependent molecular switch that modulates the activities of Kgd and Gdh. (143 aa)
glnAGlutamine synthetase, catalytic domain; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (453 aa)
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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