STRINGSTRING
ABK71916.1 ABK71916.1 cofD cofD ABK74375.1 ABK74375.1 ABK75334.1 ABK75334.1 ABK73917.1 ABK73917.1 ABK76173.1 ABK76173.1 folP-2 folP-2 fgd fgd menJ menJ ABK72597.1 ABK72597.1 FbiC FbiC folP folP
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABK71916.1Conserved hypothetical protein; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. (159 aa)
cofDLppg:fo 2-phospho-l-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (327 aa)
ABK74375.1Conserved hypothetical protein TIGR00026; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. (149 aa)
ABK75334.1Conserved hypothetical protein TIGR00026; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. (140 aa)
ABK73917.1Pyridoxamine 5'-phosphate oxidase family protein; Identified by match to protein family HMM PF01243. (167 aa)
ABK76173.1Pyridoxamine 5'-phosphate oxidase family protein; Identified by match to protein family HMM PF01243. (142 aa)
folP-2Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (285 aa)
fgdF420-dependent glucose-6-phosphate dehydrogenase; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria. Cannot use NAD, NADP, FAD or FMN instead of coenzyme F420 as an electron acceptor. Exhibits nearly no activity with D-mannose-6- phosphate or D-fructose-6-phosphate as substrate. Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family. (337 aa)
menJFAD binding domain, putative; Catalyzes the reduction of a single double bond in the isoprenoid tail of menaquinone (MK-9) in M.smegmatis, likely the beta- isoprene unit, forming the predominant form of menaquinone found in mycobacteria, MK-9(II-H2). (409 aa)
ABK72597.1Conserved hypothetical protein; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. (164 aa)
FbiCFO synthase; Identified by match to protein family HMM PF04055; match to protein family HMM TIGR00423. (874 aa)
folPDihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (291 aa)
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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