STRINGSTRING
fbiD fbiD ABK73836.1 ABK73836.1 zwf zwf ABK73410.1 ABK73410.1 ABK72261.1 ABK72261.1 ABK74466.1 ABK74466.1 ackA ackA ABK69784.1 ABK69784.1 ABK74515.1 ABK74515.1 ABK75024.1 ABK75024.1 fbiB fbiB cofD cofD ABK75334.1 ABK75334.1 ABK75053.1 ABK75053.1 ABK72942.1 ABK72942.1 ABK71229.1 ABK71229.1 FbiC FbiC ABK74121.1 ABK74121.1 ABK73602.1 ABK73602.1 ABK70230.1 ABK70230.1 zwf-2 zwf-2 tpiA tpiA gap gap tpiA-2 tpiA-2 ABK71939.1 ABK71939.1 ABK72991.1 ABK72991.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fbiDConserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (221 aa)
ABK73836.1Identified by match to protein family HMM PF00795. (299 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (495 aa)
ABK73410.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (338 aa)
ABK72261.1Monooxygenase; Identified by match to protein family HMM PF00296. (310 aa)
ABK74466.1Conserved hypothetical protein. (302 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (376 aa)
ABK69784.1Conserved hypothetical protein. (283 aa)
ABK74515.1Conserved hypothetical protein. (298 aa)
ABK75024.1Oxidoreductase; Identified by match to protein family HMM PF00296. (347 aa)
fbiBF420-0:gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. Is able to add up to six glutamates to F420-0, producing F420-3 as the major product with lesser amount of F420-4,5,6, consistent with it producing the polyglutamated F420 compounds present in Mycobacterium smegmatis. In the N-terminal section; belong [...] (454 aa)
cofDLppg:fo 2-phospho-l-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (327 aa)
ABK75334.1Conserved hypothetical protein TIGR00026; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. (140 aa)
ABK75053.1Oxidoreductase; Identified by match to protein family HMM PF00296. (345 aa)
ABK72942.1Monooxygenase; Identified by match to protein family HMM PF00296. (306 aa)
ABK71229.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (330 aa)
FbiCFO synthase; Identified by match to protein family HMM PF04055; match to protein family HMM TIGR00423. (874 aa)
ABK74121.1Conserved hypothetical protein. (295 aa)
ABK73602.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (772 aa)
ABK70230.1Hydride transferase 1; Identified by match to protein family HMM PF00296. (327 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (516 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase, type I; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. (340 aa)
tpiA-2Triosephosphate isomerase; Catalyzes the isomerization of L-erythrulose-1P to D- erythrulose-4P. Involved in the degradation pathway of L-threitol, that allows M.smegmatis to grow on this compound as the sole carbon source. Belongs to the triosephosphate isomerase family. (263 aa)
ABK71939.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (329 aa)
ABK72991.1Conserved hypothetical protein. (350 aa)
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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