STRINGSTRING
pyk pyk ABK69584.1 ABK69584.1 pckG pckG ABK74973.1 ABK74973.1 ABK71023.1 ABK71023.1 ABK74396.1 ABK74396.1 ABK71965.1 ABK71965.1 ABK69877.1 ABK69877.1 ABK74101.1 ABK74101.1 ABK72872.1 ABK72872.1 ABK70948.1 ABK70948.1 fbaA fbaA ABK72432.1 ABK72432.1 lpdA lpdA gpmA gpmA adhc1 adhc1 ABK70904.1 ABK70904.1 ABK69654.1 ABK69654.1 ABK73984.1 ABK73984.1 ABK69777.1 ABK69777.1 ABK72542.1 ABK72542.1 ABK71277.1 ABK71277.1 pgm pgm ABK69681.1 ABK69681.1 ABK73288.1 ABK73288.1 ABK73518.1 ABK73518.1 ABK73648.1 ABK73648.1 gap gap pgk pgk tpiA tpiA pyk-2 pyk-2 ABK73649.1 ABK73649.1 ABK73360.1 ABK73360.1 ABK75946.1 ABK75946.1 ABK72273.1 ABK72273.1 ABK69640.1 ABK69640.1 ABK73027.1 ABK73027.1 aceE aceE orB orB ABK76139.1 ABK76139.1 ABK72864.1 ABK72864.1 ABK74408.1 ABK74408.1 ABK70172.1 ABK70172.1 ABK73918.1 ABK73918.1 glpX glpX eno eno pgi pgi ABK72632.1 ABK72632.1 ABK73436.1 ABK73436.1 ABK69616.1 ABK69616.1 acsA acsA ABK71285.1 ABK71285.1 ABK70572.1 ABK70572.1 ABK72883.1 ABK72883.1 ABK75692.1 ABK75692.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pykPyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (477 aa)
ABK69584.1Alcohol dehydrogenase B; Identified by match to protein family HMM PF00107. (374 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (608 aa)
ABK74973.1Aldehyde-alcohol dehydrogenase; Identified by match to protein family HMM PF00171. (527 aa)
ABK71023.1Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (497 aa)
ABK74396.1Aldehyde dehydrogenase; Identified by match to protein family HMM PF00171. (500 aa)
ABK71965.1Aldehyde dehydrogenase; Identified by match to protein family HMM PF00171. (475 aa)
ABK69877.1Glucosidase; Identified by match to protein family HMM PF02056. (458 aa)
ABK74101.1acetyl-CoA synthetase, putative; Identified by match to protein family HMM PF02629. (675 aa)
ABK72872.1Aldose 1-epimerase subfamily protein; Identified by match to protein family HMM PF01263. (300 aa)
ABK70948.1acetyl-CoA synthetase; Identified by match to protein family HMM PF00501. (549 aa)
fbaAFructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (345 aa)
ABK72432.1Eptc-inducible aldehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (507 aa)
lpdADihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350. (464 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa)
adhc1Alcohol dehydrogenase, zinc-containing; Prefers aldehydes over alcohols. (349 aa)
ABK70904.1Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (507 aa)
ABK69654.1Glucokinase; Identified by match to protein family HMM PF00480. (301 aa)
ABK73984.1Tagatose-1,6-bisphosphate aldolase GatY; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167. (280 aa)
ABK69777.1Eptc-inducible aldehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (514 aa)
ABK72542.1Piperideine-6-carboxylic acid dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (527 aa)
ABK71277.1Beta-glucoside-specific EII permease; Identified by match to protein family HMM PF00358; match to protein family HMM TIGR00830. (156 aa)
pgmPhosphoglucomutase, alpha-D-glucose phosphate-specific; Identified by similarity to SP:P36938; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; match to protein family HMM TIGR01132. (544 aa)
ABK69681.1Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (508 aa)
ABK73288.1Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (494 aa)
ABK73518.1Polyphosphate glucokinase; Identified by match to protein family HMM PF00480. (272 aa)
ABK73648.1Aldehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (473 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase, type I; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. (340 aa)
pgkPhosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (408 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
pyk-2Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (472 aa)
ABK73649.1Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (517 aa)
ABK73360.1Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. (297 aa)
ABK75946.1Zinc-binding alcohol dehydrogenase family protein; Identified by match to protein family HMM PF00107; match to protein family HMM TIGR02822. (337 aa)
ABK72273.1Alcohol dehydrogenase; Identified by match to protein family HMM PF01011; match to protein family HMM TIGR03075. (561 aa)
ABK69640.1NAD-dependent alcohol dehydrogenase; Identified by match to protein family HMM PF00107. (356 aa)
ABK73027.1Acetyl-coenzyme A synthetase; Identified by match to protein family HMM PF00501. (543 aa)
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2- oxoglutarate (By similarity). (929 aa)
orBAlpha oxoglutarate ferredoxin oxidoreductase, beta subunit; Identified by match to protein family HMM PF02775. (342 aa)
ABK76139.1Pyruvate synthase; Identified by match to protein family HMM PF01855. (651 aa)
ABK72864.1Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. (406 aa)
ABK74408.1Pyruvate dehydrogenase E1 component subunit beta; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780. (358 aa)
ABK70172.1Pyruvate dehydrogenase E1 component, alpha subunit; Identified by match to protein family HMM PF00676. (370 aa)
ABK73918.1Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (490 aa)
glpXFructose-1,6-bisphosphatase, class II; Identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330. (342 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
pgiGlucose-6-phosphate isomerase; Identified by similarity to SP:P11537; match to protein family HMM PF00342; Belongs to the GPI family. (549 aa)
ABK72632.1AMP-dependent synthetase and ligase; Identified by match to protein family HMM PF00501. (562 aa)
ABK73436.1Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (489 aa)
ABK69616.1Alcohol dehydrogenase B; Identified by match to protein family HMM PF00107. (375 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (940 aa)
ABK71285.11,3-propanediol dehydrogenase; Identified by match to protein family HMM PF00465. (399 aa)
ABK70572.1Phosphoglycerate mutase family protein, putative; Identified by match to protein family HMM PF00300. (202 aa)
ABK72883.1Alcohol dehydrogenase; Identified by match to protein family HMM PF00107. (359 aa)
ABK75692.1Identified by match to protein family HMM PF00480. (320 aa)
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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