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ABK71393.1 ABK71393.1 SdhA SdhA ABK70472.1 ABK70472.1 sdhB sdhB sdhA sdhA ABK75821.1 ABK75821.1 sdhC sdhC ABK73723.1 ABK73723.1 nuoN nuoN nuoM nuoM nuoL nuoL nuoK nuoK ABK74789.1 ABK74789.1 nuoI nuoI nuoH nuoH nuoG nuoG nuoF nuoF ABK71308.1 ABK71308.1 nuoD nuoD nuoC nuoC nuoB nuoB nuoA nuoA ppk ppk cyoE cyoE ABK72041.1 ABK72041.1 cydB cydB ABK70723.1 ABK70723.1 ABK69556.1 ABK69556.1 ndh ndh ABK69740.1 ABK69740.1 ABK75074.1 ABK75074.1 ABK75942.1 ABK75942.1 ABK73621.1 ABK73621.1 ABK74914.1 ABK74914.1 ABK75372.1 ABK75372.1 ctaD ctaD atpC atpC atpD atpD atpG atpG atpA atpA atpFH atpFH atpF atpF atpE atpE atpB atpB ABK75613.1 ABK75613.1 ABK74312.1 ABK74312.1 ABK71865.1 ABK71865.1 ppa ppa ABK69656.1 ABK69656.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ABK71393.1Succinate dehydrogenase; Identified by match to protein family HMM PF00111; match to protein family HMM TIGR00384. (249 aa)
SdhASuccinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM PF07992. (635 aa)
ABK70472.1Polyphosphate kinase 2; Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP; Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily. (283 aa)
sdhBSuccinate dehydrogenase, iron-sulfur protein; Identified by similarity to SP:P51053; match to protein family HMM TIGR00384. (261 aa)
sdhASuccinate dehydrogenase, flavoprotein subunit; Identified by similarity to SP:P31038; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01812; match to protein family HMM TIGR01816. (584 aa)
ABK75821.1Succinate dehydrogenase hydrophobic membrane anchor protein SdhD. (156 aa)
sdhCSuccinate dehydrogenase, cytochrome b556 subunit; Identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970. (138 aa)
ABK73723.1Succinate dehydrogenase [ubiquinone] flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF02910. (578 aa)
nuoNNADH-quinone oxidoreductase, N subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (521 aa)
nuoMNADH-quinone oxidoreductase, M subunit; Identified by similarity to SP:P50974; match to protein family HMM PF00361; match to protein family HMM TIGR01972. (529 aa)
nuoLNADH-quinone oxidoreductase, L subunit; Identified by match to protein family HMM PF00361; match to protein family HMM PF00662; match to protein family HMM TIGR01974. (629 aa)
nuoKNADH-quinone oxidoreductase, k subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (99 aa)
ABK74789.1NADH dehydrogenase subunit j; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (252 aa)
nuoINADH-quinone oxidoreductase, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa)
nuoHNADH-quinone oxidoreductase, H subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity). (408 aa)
nuoGNADH-quinone oxidoreductase, G subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (794 aa)
nuoFNADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (443 aa)
ABK71308.1NADH-quinone oxidoreductase chain e; Identified by match to protein family HMM PF01257; match to protein family HMM TIGR01958. (245 aa)
nuoDNADH-quinone oxidoreducatase, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (442 aa)
nuoCNADH-quinone oxidoreductase chain c; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. (238 aa)
nuoBNADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
nuoANADH-quinone oxidoreductase, a subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (122 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (736 aa)
cyoEProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (308 aa)
ABK72041.1Cytochrome aa3 controlling protein; Identified by match to protein family HMM PF02628. (320 aa)
cydBCytochrome D ubiquinol oxidase, subunit II; Identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203. (350 aa)
ABK70723.1Cytochrome D ubiquinol oxidase subunit 1; Identified by match to protein family HMM PF01654. (487 aa)
ABK69556.1DoxD family protein/pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992. (453 aa)
ndhNADH dehydrogenase; Identified by similarity to GB:AAC46302.1; match to protein family HMM PF00070; match to protein family HMM PF07992. (457 aa)
ABK69740.1Cytochrome c oxidase subunit 3; Identified by match to protein family HMM PF00510. (203 aa)
ABK75074.1Ubiquinol-cytochrome c reductase cytochrome c subunit; Identified by match to protein family HMM PF00034. (268 aa)
ABK75942.1Ubiquinol-cytochrome c reductase iron-sulfur subunit; Identified by match to protein family HMM PF00355. (408 aa)
ABK73621.1Ubiquinol-cytochrome c reductase cytochrome b subunit; Identified by match to protein family HMM PF00033. (546 aa)
ABK74914.1Cytochrome c oxidase subunit 2; Identified by match to protein family HMM PF00116. (341 aa)
ABK75372.1Dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992. (472 aa)
ctaDCytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (583 aa)
atpCATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (121 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (475 aa)
atpGATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (307 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (548 aa)
atpFHATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). (445 aa)
atpFBacteriophage lysis protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (170 aa)
atpEATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (86 aa)
atpBATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (252 aa)
ABK75613.1Dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992. (397 aa)
ABK74312.1Cytochrome bd ubiquinol oxidase, subunit I; Identified by match to protein family HMM PF01654. (462 aa)
ABK71865.1Cytochrome bd-I oxidase subunit II; Identified by match to protein family HMM PF02322. (332 aa)
ppaInorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (162 aa)
ABK69656.1Dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992. (400 aa)
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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