STRINGSTRING
ABK75546.1 ABK75546.1 ABK74648.1 ABK74648.1 ABK73120.1 ABK73120.1 ABK69733.1 ABK69733.1 ABK69584.1 ABK69584.1 ABK70948.1 ABK70948.1 fbaA fbaA pta pta ackA ackA gpmA gpmA serB serB ABK73984.1 ABK73984.1 fbiB fbiB cofD cofD ABK74447.1 ABK74447.1 ABK70857.1 ABK70857.1 serA serA fbiD fbiD ABK72224.1 ABK72224.1 ppc ppc ABK72595.1 ABK72595.1 ABK73360.1 ABK73360.1 ABK73027.1 ABK73027.1 FbiC FbiC glpX glpX glyA glyA eno eno ABK72632.1 ABK72632.1 serC serC ABK69616.1 ABK69616.1 acsA acsA ABK73839.1 ABK73839.1 ABK71222.1 ABK71222.1 ABK76114.1 ABK76114.1 ABK73420.1 ABK73420.1 ABK70572.1 ABK70572.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABK75546.1Formate dehydrogenase, gamma subunit; Identified by similarity to GB:CAA11233.1; match to protein family HMM PF01257. (161 aa)
ABK74648.1Formate dehydrogenase, beta subunit; Identified by similarity to GB:CAA11234.1; match to protein family HMM PF01512. (532 aa)
ABK73120.1Formate dehydrogenase, alpha subunit; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01591. (939 aa)
ABK69733.1NAD-dependent formate dehydrogenase delta subunit. (74 aa)
ABK69584.1Alcohol dehydrogenase B; Identified by match to protein family HMM PF00107. (374 aa)
ABK70948.1acetyl-CoA synthetase; Identified by match to protein family HMM PF00501. (549 aa)
fbaAFructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (345 aa)
ptaPhosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (692 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (376 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa)
serBPhosphoserine phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM PF01842; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488. (413 aa)
ABK73984.1Tagatose-1,6-bisphosphate aldolase GatY; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167. (280 aa)
fbiBF420-0:gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. Is able to add up to six glutamates to F420-0, producing F420-3 as the major product with lesser amount of F420-4,5,6, consistent with it producing the polyglutamated F420 compounds present in Mycobacterium smegmatis. In the N-terminal section; belong [...] (454 aa)
cofDLppg:fo 2-phospho-l-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (327 aa)
ABK74447.14Fe-4S ferredoxin, iron-sulfur binding protein; Identified by match to protein family HMM PF00037. (304 aa)
ABK70857.15,10-methylenetetrahydromethanopterin reductase. (299 aa)
serAD-3-phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF01842; match to protein family HMM PF02826; match to protein family HMM TIGR01327; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa)
fbiDConserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (221 aa)
ABK72224.15,10-methylenetetrahydromethanopterin reductase; Identified by match to protein family HMM PF00296. (332 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (933 aa)
ABK72595.15,10-methylenetetrahydromethanopterin reductase; Identified by match to protein family HMM PF00296. (337 aa)
ABK73360.1Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. (297 aa)
ABK73027.1Acetyl-coenzyme A synthetase; Identified by match to protein family HMM PF00501. (543 aa)
FbiCFO synthase; Identified by match to protein family HMM PF04055; match to protein family HMM TIGR00423. (874 aa)
glpXFructose-1,6-bisphosphatase, class II; Identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330. (342 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (490 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
ABK72632.1AMP-dependent synthetase and ligase; Identified by match to protein family HMM PF00501. (562 aa)
serCPhosphoserine aminotransferase, putative; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (370 aa)
ABK69616.1Alcohol dehydrogenase B; Identified by match to protein family HMM PF00107. (375 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (940 aa)
ABK73839.1Alcohol dehydrogenase, iron-containing; Identified by match to protein family HMM PF00465. (423 aa)
ABK71222.1Glutamine amidotransferase, class II; Identified by match to protein family HMM PF00310. (289 aa)
ABK76114.1Identified by match to protein family HMM PF01493. (231 aa)
ABK73420.1Identified by match to protein family HMM PF01070; match to protein family HMM PF01180; match to protein family HMM PF01645; Belongs to the glutamate synthase family. (446 aa)
ABK70572.1Phosphoglycerate mutase family protein, putative; Identified by match to protein family HMM PF00300. (202 aa)
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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