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| | ABK74137.1 | 6-phosphogluconate dehydrogenase, decarboxylating; Identified by match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM TIGR00872. (297 aa) |
| | pyk | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (477 aa) |
| | ABK75546.1 | Formate dehydrogenase, gamma subunit; Identified by similarity to GB:CAA11233.1; match to protein family HMM PF01257. (161 aa) |
| | ABK74648.1 | Formate dehydrogenase, beta subunit; Identified by similarity to GB:CAA11234.1; match to protein family HMM PF01512. (532 aa) |
| | ABK73120.1 | Formate dehydrogenase, alpha subunit; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01591. (939 aa) |
| | ABK69733.1 | NAD-dependent formate dehydrogenase delta subunit. (74 aa) |
| | ABK69584.1 | Alcohol dehydrogenase B; Identified by match to protein family HMM PF00107. (374 aa) |
| | eda | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by similarity to SP:P10177; match to protein family HMM PF01081; match to protein family HMM TIGR01182. (209 aa) |
| | edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (609 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (495 aa) |
| | ABK72823.1 | Acetyl-/propionyl-coenzyme A carboxylase alpha chain; Identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF01071; match to protein family HMM PF02785; match to protein family HMM PF02786. (669 aa) |
| | ABK70351.1 | 3-ketoacyl-CoA thiolase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family. (432 aa) |
| | ABK71393.1 | Succinate dehydrogenase; Identified by match to protein family HMM PF00111; match to protein family HMM TIGR00384. (249 aa) |
| | SdhA | Succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM PF07992. (635 aa) |
| | aroK | Shikimate kinase; Identified by match to protein family HMM PF01202; match to protein family HMM TIGR01313. (170 aa) |
| | ABK73843.1 | Formamidase; Identified by match to protein family HMM PF03069. (369 aa) |
| | ABK70948.1 | acetyl-CoA synthetase; Identified by match to protein family HMM PF00501. (549 aa) |
| | fbaA | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (345 aa) |
| | pta | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (692 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (376 aa) |
| | lpdA | Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350. (464 aa) |
| | aceA | Isocitrate lyase; Identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346. (428 aa) |
| | ABK71785.1 | 3-hydroxybutyryl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737. (286 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa) |
| | serB | Phosphoserine phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM PF01842; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488. (413 aa) |
| | ABK69737.1 | Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342. (654 aa) |
| | ABK76007.1 | Gluconolactonase; Identified by match to protein family HMM PF03758. (375 aa) |
| | ABK69654.1 | Glucokinase; Identified by match to protein family HMM PF00480. (301 aa) |
| | ABK73984.1 | Tagatose-1,6-bisphosphate aldolase GatY; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167. (280 aa) |
| | mmsA | Methylmalonate-semialdehyde dehydrogenase; Identified by similarity to GB:AAA99190.1; match to protein family HMM PF00171; match to protein family HMM TIGR01722. (506 aa) |
| | folD | Tetrahydrofolate dehydrogenase/cyclohydrolase FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa) |
| | ABK69615.1 | Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF03971; match to protein family HMM TIGR00178; Belongs to the monomeric-type IDH family. (743 aa) |
| | sdhB | Succinate dehydrogenase, iron-sulfur protein; Identified by similarity to SP:P51053; match to protein family HMM TIGR00384. (261 aa) |
| | sdhA | Succinate dehydrogenase, flavoprotein subunit; Identified by similarity to SP:P31038; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01812; match to protein family HMM TIGR01816. (584 aa) |
| | ABK75821.1 | Succinate dehydrogenase hydrophobic membrane anchor protein SdhD. (156 aa) |
| | sdhC | Succinate dehydrogenase, cytochrome b556 subunit; Identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970. (138 aa) |
| | ABK73723.1 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF02910. (578 aa) |
| | ABK71291.1 | Acetyl-/propionyl-coenzyme A carboxylase alpha chain; Identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02222; match to protein family HMM PF02785; match to protein family HMM PF02786. (598 aa) |
| | ABK74100.1 | propionyl-CoA carboxylase beta chain; Identified by match to protein family HMM PF01039. (542 aa) |
| | ABK74447.1 | 4Fe-4S ferredoxin, iron-sulfur binding protein; Identified by match to protein family HMM PF00037. (304 aa) |
| | ABK71539.1 | Beta-ketothiolase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family. (410 aa) |
| | ABK74157.1 | MaoC like domain protein; Identified by match to protein family HMM PF01575. (277 aa) |
| | ABK70857.1 | 5,10-methylenetetrahydromethanopterin reductase. (299 aa) |
| | ABK72539.1 | Transketolase, N- subunit; Identified by match to protein family HMM PF00456. (287 aa) |
| | ABK73739.1 | Transketoloase, C half; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780. (344 aa) |
| | ABK76118.1 | Beta-ketothiolase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa) |
| | ABK73024.1 | acetyl-CoA C-acyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | ABK73835.1 | Putative thiolase; Identified by match to protein family HMM PF02803; Belongs to the thiolase-like superfamily. Thiolase family. (382 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF01842; match to protein family HMM PF02826; match to protein family HMM TIGR01327; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa) |
| | pyc | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1127 aa) |
| | mmsA-2 | Methylmalonate-semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01722. (497 aa) |
| | ABK72224.1 | 5,10-methylenetetrahydromethanopterin reductase; Identified by match to protein family HMM PF00296. (332 aa) |
| | ABK69766.1 | L-carnitine dehydratase/bile acid-inducible protein F; Identified by match to protein family HMM PF02515; Belongs to the CoA-transferase III family. (411 aa) |
| | mqo | Malate:quinone-oxidoreductase; Identified by match to protein family HMM PF01266; match to protein family HMM PF06039; match to protein family HMM TIGR01320. (510 aa) |
| | ABK73518.1 | Polyphosphate glucokinase; Identified by match to protein family HMM PF00480. (272 aa) |
| | ABK74739.1 | 2-Keto-3-deoxy-gluconate kinase; Identified by match to protein family HMM PF00294. (307 aa) |
| | ABK72215.1 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (545 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Identified by similarity to SP:P46969; match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase, type I; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. (340 aa) |
| | pgk | Phosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (408 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (933 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (244 aa) |
| | zwf-2 | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (516 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (371 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (696 aa) |
| | acnA | Aconitate hydratase 1; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. The apo form of AcnA functions as a RNA-binding regulatory protein. Could catalyze the hydration of 2-methyl-cis- aconitate to yield (2R,3S)-2-methylisocitrate. (943 aa) |
| | mutA | methylmalonyl-CoA mutase, small subunit; Identified by match to protein family HMM PF01642; match to protein family HMM TIGR00642. (623 aa) |
| | ABK74995.1 | methylmalonyl-CoA mutase large subunit; Identified by match to protein family HMM PF01642; match to protein family HMM PF02310; match to protein family HMM TIGR00640; match to protein family HMM TIGR00641. (751 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (430 aa) |
| | pyk-2 | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (472 aa) |
| | derI1 | Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of erythritol and D- threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family. (153 aa) |
| | amiF | Formamidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. (333 aa) |
| | sdaA | L-serine ammonia-lyase; Identified by similarity to SP:P16095; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa) |
| | ABK72595.1 | 5,10-methylenetetrahydromethanopterin reductase; Identified by match to protein family HMM PF00296. (337 aa) |
| | katA | Catalase KatA; Identified by similarity to SP:P26901; match to protein family HMM PF00199. (485 aa) |
| | ABK73360.1 | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. (297 aa) |
| | ABK75565.1 | acetyl-CoA acetyltransferase. (488 aa) |
| | gnd | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (488 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (721 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (946 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (131 aa) |
| | aceA-2 | Isocitrate lyase; Identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346. (769 aa) |
| | ABK74752.1 | Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. (359 aa) |
| | ABK76135.1 | PfkB-family protein carbohydrate kinase; Identified by match to protein family HMM PF00294. (331 aa) |
| | eda-2 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182. (209 aa) |
| | ABK73027.1 | Acetyl-coenzyme A synthetase; Identified by match to protein family HMM PF00501. (543 aa) |
| | ABK73320.1 | Citrate synthase; Belongs to the citrate synthase family. (271 aa) |
| | ABK75159.1 | 3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737. (280 aa) |
| | ABK71837.1 | 3-hydroxybutyryl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737. (293 aa) |
| | ABK71555.1 | 3-hydroxybutyryl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737. (296 aa) |
| | ABK70332.1 | 3-hydroxybutyryl-CoA dehydratase; Identified by match to protein family HMM PF00378. (262 aa) |
| | ABK74493.1 | 3-hydroxybutyryl-CoA dehydratase; Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (238 aa) |
| | ABK73370.1 | Identified by match to protein family HMM PF01575. (144 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (365 aa) |
| | sucB | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM TIGR02927. (585 aa) |
| | aceE | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2- oxoglutarate (By similarity). (929 aa) |
| | ABK75426.1 | propionyl-CoA carboxylase beta chain; Identified by match to protein family HMM PF01039. (474 aa) |
| | ABK70045.1 | Formamidase; Identified by match to protein family HMM PF03069. (418 aa) |
| | tal-2 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (370 aa) |
| | ABK74088.1 | Transketolase; Identified by match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780. (644 aa) |
| | ABK75534.1 | acyl-CoA oxidase; Identified by match to protein family HMM PF00441; match to protein family HMM PF01756; match to protein family HMM PF02770. (640 aa) |
| | orB | Alpha oxoglutarate ferredoxin oxidoreductase, beta subunit; Identified by match to protein family HMM PF02775. (342 aa) |
| | ABK76139.1 | Pyruvate synthase; Identified by match to protein family HMM PF01855. (651 aa) |
| | ABK71161.1 | Ribose 5-phosphate isomerase; Identified by match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR02133. (159 aa) |
| | ABK72864.1 | Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. (406 aa) |
| | ABK74408.1 | Pyruvate dehydrogenase E1 component subunit beta; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780. (358 aa) |
| | ABK70172.1 | Pyruvate dehydrogenase E1 component, alpha subunit; Identified by match to protein family HMM PF00676. (370 aa) |
| | ABK71132.1 | Acetyl-/propionyl-coenzyme A carboxylase alpha chain; Identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786. (669 aa) |
| | ABK71586.1 | Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (242 aa) |
| | ABK71062.1 | methylmalonyl-CoA mutase C-terminal domain protein; Identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640. (132 aa) |
| | ABK76209.1 | methylmalonyl-CoA mutase, N-terminus of large subunit; Identified by match to protein family HMM PF01642; match to protein family HMM TIGR00641. (529 aa) |
| | ABK71664.1 | acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930. (411 aa) |
| | mce | methylmalonyl-CoA epimerase; Identified by match to protein family HMM PF00903; match to protein family HMM TIGR03081. (157 aa) |
| | ABK69749.1 | NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949. (380 aa) |
| | glpX | Fructose-1,6-bisphosphatase, class II; Identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330. (342 aa) |
| | fumC | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (468 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (490 aa) |
| | ABK69698.1 | Beta-ketoadipyl CoA thiolase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa) |
| | ABK74508.1 | Formamidase; Identified by match to protein family HMM PF03069. (415 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa) |
| | ABK70078.1 | Acetyl-/propionyl-coenzyme A carboxylase alpha chain; Identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786. (648 aa) |
| | ABK70236.1 | acetyl-CoA acetyltransferase. (507 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa) |
| | pgi | Glucose-6-phosphate isomerase; Identified by similarity to SP:P11537; match to protein family HMM PF00342; Belongs to the GPI family. (549 aa) |
| | ABK75978.1 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa) |
| | ABK72632.1 | AMP-dependent synthetase and ligase; Identified by match to protein family HMM PF00501. (562 aa) |
| | gltA | Citrate synthase I; Identified by similarity to SP:P42457; match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. (434 aa) |
| | ABK75407.1 | Citrate synthase; Identified by match to protein family HMM PF00285; Belongs to the citrate synthase family. (377 aa) |
| | serC | Phosphoserine aminotransferase, putative; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (370 aa) |
| | ABK75990.1 | Putative 3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. (720 aa) |
| | ABK72156.1 | acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa) |
| | ABK69616.1 | Alcohol dehydrogenase B; Identified by match to protein family HMM PF00107. (375 aa) |
| | ABK75469.1 | acetyl-CoA acetyltransferase. (392 aa) |
| | cysE | Serine O-acetyltransferase. (172 aa) |
| | ABK75580.1 | acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa) |
| | ABK72416.1 | acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family. (382 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (940 aa) |
| | ABK74603.1 | Cysteine synthase/cystathionine beta-synthase family protein; Identified by match to protein family HMM PF00291. (365 aa) |
| | katA-2 | Catalase KatA; Identified by similarity to SP:P26901; match to protein family HMM PF00199. (553 aa) |
| | ABK73839.1 | Alcohol dehydrogenase, iron-containing; Identified by match to protein family HMM PF00465. (423 aa) |
| | ABK70572.1 | Phosphoglycerate mutase family protein, putative; Identified by match to protein family HMM PF00300. (202 aa) |
| | ABK73929.1 | Citrate synthase 2; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family. (376 aa) |
| | pyc-2 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1131 aa) |
| | ABK73488.1 | Methylenetetrahydrofolate reductase family protein, putative; Identified by match to protein family HMM PF02219; Belongs to the methylenetetrahydrofolate reductase family. (281 aa) |
| | derI2 | Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of L-threitol, D- threitol and erythritol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family. (152 aa) |
| | ABK76045.1 | 3-hydroxybutyryl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF01210; match to protein family HMM PF02737; match to protein family HMM PF03446. (320 aa) |
| | ABK75692.1 | Identified by match to protein family HMM PF00480. (320 aa) |
