STRINGSTRING
accC accC cls cls upp upp MXAN_0147 MXAN_0147 MXAN_0256 MXAN_0256 MXAN_0302 MXAN_0302 MXAN_0386 MXAN_0386 atpB atpB atpE atpE atpF atpF MXAN_0414 MXAN_0414 MXAN_0420 MXAN_0420 MXAN_0450 MXAN_0450 MXAN_0452 MXAN_0452 pdxA pdxA nudC nudC MXAN_0496 MXAN_0496 MXAN_0537 MXAN_0537 MXAN_0564 MXAN_0564 MXAN_0604 MXAN_0604 MXAN_0609 MXAN_0609 MXAN_0628 MXAN_0628 MXAN_0639 MXAN_0639 MXAN_0753 MXAN_0753 MXAN_0761 MXAN_0761 MXAN_0788 MXAN_0788 MXAN_0873 MXAN_0873 MXAN_0888 MXAN_0888 MXAN_0902 MXAN_0902 kmo kmo kynU kynU nbaC nbaC MXAN_0949 MXAN_0949 gnd gnd pgl pgl zwf zwf MXAN_0955 MXAN_0955 MXAN_1075 MXAN_1075 pyrG pyrG purF purF pccA pccA gpmI gpmI MXAN_1273 MXAN_1273 pdxH pdxH gpsA gpsA MXAN_1362 MXAN_1362 MXAN_1364 MXAN_1364 glmU glmU pssA pssA MXAN_1438 MXAN_1438 plsY plsY add add MXAN_1530 MXAN_1530 MXAN_1596 MXAN_1596 MXAN_1648 MXAN_1648 MXAN_1675 MXAN_1675 MXAN_1718 MXAN_1718 MXAN_1828 MXAN_1828 suhB suhB MXAN_1944 MXAN_1944 MXAN_1946 MXAN_1946 moaC moaC MXAN_1974 MXAN_1974 maf maf MXAN_2005 MXAN_2005 MXAN_2022 MXAN_2022 MXAN_2047 MXAN_2047 MXAN_2048 MXAN_2048 MXAN_2054 MXAN_2054 dut dut purB purB purC purC MXAN_2106 MXAN_2106 MXAN_2219 MXAN_2219 MXAN_2224 MXAN_2224 folD folD MXAN_2228 MXAN_2228 MXAN_2236 MXAN_2236 MXAN_2252 MXAN_2252 thiD thiD coaA coaA purL purL MXAN_2369 MXAN_2369 MXAN_2418 MXAN_2418 MXAN_2442 MXAN_2442 MXAN_2470 MXAN_2470 MXAN_2494 MXAN_2494 purK purK purE purE plsX plsX MXAN_2556 MXAN_2556 moaDE moaDE acsA acsA cobC cobC tmk-2 tmk-2 MXAN_2590 MXAN_2590 MXAN_2591 MXAN_2591 nadA nadA purA purA maf-2 maf-2 MXAN_2661 MXAN_2661 pdhA pdhA pdhC pdhC MXAN_2679 MXAN_2679 MXAN_2692 MXAN_2692 purN purN purM purM MXAN_2703 MXAN_2703 accD accD MXAN_2723 MXAN_2723 moaB moaB MXAN_2813 MXAN_2813 pgk pgk tpiA tpiA MXAN_2901 MXAN_2901 pssA-2 pssA-2 purH purH purD purD MXAN_2955 MXAN_2955 coaE coaE pyrD pyrD MXAN_3029 MXAN_3029 folD-2 folD-2 MXAN_3123 MXAN_3123 MXAN_3191 MXAN_3191 MXAN_3199 MXAN_3199 relA relA MXAN_3267 MXAN_3267 thiG thiG thiS thiS MXAN_3288 MXAN_3288 adk adk MXAN_3330 MXAN_3330 MXAN_3331 MXAN_3331 MXAN_3352 MXAN_3352 MXAN_3383 MXAN_3383 coaD coaD carB carB tmk tmk MXAN_3437 MXAN_3437 MXAN_3454 MXAN_3454 pyrB pyrB pyrC pyrC carA carA pyk pyk ndk ndk MXAN_3659 MXAN_3659 psd psd MXAN_3743 MXAN_3743 guaA guaA guaB guaB tesB tesB MXAN_3927 MXAN_3927 taF taF taC taC MXAN_3956 MXAN_3956 MXAN_3968 MXAN_3968 MXAN_3969 MXAN_3969 MXAN_3975 MXAN_3975 pfkA pfkA MXAN_4028 MXAN_4028 cmk cmk accA accA MXAN_4044 MXAN_4044 MXAN_4067 MXAN_4067 MXAN_4069 MXAN_4069 MXAN_4086 MXAN_4086 coaX coaX udk udk nadD nadD MXAN_4188 MXAN_4188 MXAN_4207 MXAN_4207 moeA moeA MXAN_4217 MXAN_4217 MXAN_4223 MXAN_4223 moaA moaA thiC thiC mvaS mvaS MXAN_4280 MXAN_4280 MXAN_4313 MXAN_4313 MXAN_4341 MXAN_4341 nnrD nnrD MXAN_4364 MXAN_4364 MXAN_4385 MXAN_4385 coaBC coaBC surE surE eno eno nadC nadC MXAN_4545 MXAN_4545 MXAN_4564 MXAN_4564 MXAN_4617 MXAN_4617 pgsA pgsA nadB nadB pyrE pyrE dxs dxs MXAN_4683 MXAN_4683 gmk gmk lpxK lpxK lpxB lpxB MXAN_4719 MXAN_4719 MXAN_4723 MXAN_4723 lpxA lpxA fabZ fabZ lpxD lpxD MXAN_4741 MXAN_4741 plsX-2 plsX-2 MXAN_4882 MXAN_4882 lpxC lpxC mvaD mvaD MXAN_5020 MXAN_5020 MXAN_5058 MXAN_5058 hpt hpt MXAN_5071 MXAN_5071 tdk tdk prs prs MXAN_5085 MXAN_5085 thiE thiE MXAN_5109 MXAN_5109 MXAN_5140 MXAN_5140 MXAN_5163 MXAN_5163 MXAN_5232 MXAN_5232 MXAN_5238 MXAN_5238 MXAN_5282 MXAN_5282 MXAN_5325 MXAN_5325 pyrH pyrH apt apt coaD-2 coaD-2 MXAN_5361 MXAN_5361 nadK nadK MXAN_5370 MXAN_5370 rpiA rpiA MXAN_5527 MXAN_5527 gpmA gpmA MXAN_5575 MXAN_5575 MXAN_5578 MXAN_5578 MXAN_5585 MXAN_5585 MXAN_5689 MXAN_5689 deoC deoC MXAN_5761 MXAN_5761 accC-3 accC-3 ribF ribF acsA-2 acsA-2 pyrF pyrF tal tal thyA thyA MXAN_5950 MXAN_5950 sucB sucB MXAN_6070 MXAN_6070 MXAN_6110 MXAN_6110 MXAN_6147 MXAN_6147 MXAN_6252 MXAN_6252 MXAN_6266 MXAN_6266 MXAN_6270 MXAN_6270 pyk-2 pyk-2 MXAN_6319 MXAN_6319 pfkA-2 pfkA-2 MXAN_6383 MXAN_6383 fabZ-2 fabZ-2 MXAN_6397 MXAN_6397 MXAN_6408 MXAN_6408 MXAN_6430 MXAN_6430 MXAN_6431 MXAN_6431 MXAN_6495 MXAN_6495 MXAN_6513 MXAN_6513 MXAN_6543 MXAN_6543 MXAN_6690 MXAN_6690 thiL thiL MXAN_6707 MXAN_6707 MXAN_6724 MXAN_6724 MXAN_6743 MXAN_6743 MXAN_6753 MXAN_6753 glpK glpK nadE nadE pgi pgi atpC atpC atpD atpD atpG atpG MXAN_6972 MXAN_6972 atpH atpH atpA atpA MXAN_7138 MXAN_7138 MXAN_7156 MXAN_7156 MXAN_7166 MXAN_7166 MXAN_7193 MXAN_7193 MXAN_7243 MXAN_7243 MXAN_7285 MXAN_7285 MXAN_7302 MXAN_7302 glpD glpD tkt tkt MXAN_7396 MXAN_7396 MXAN_7403 MXAN_7403 mobA mobA moeA-2 moeA-2 mobB/FdhD mobB/FdhD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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accCacetyl-CoA carboxylase, biotin carboxylase; Identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786; match to protein family HMM TIGR00514. (664 aa)
clsCardiolipin synthase; Identified by similarity to SP:P31071; match to protein family HMM PF00614. (415 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa)
MXAN_0147Putative acetyltransferase; Identified by match to protein family HMM PF01553. (282 aa)
MXAN_0256Aminotransferase, class V; Identified by match to protein family HMM PF00266; match to protein family HMM PF01212. (386 aa)
MXAN_0302Radical SAM domain protein; Identified by match to protein family HMM PF04055. (262 aa)
MXAN_0386Identified by match to protein family HMM PF00903. (129 aa)
atpBATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (303 aa)
atpEATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (76 aa)
atpFATP synthase F0, B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (172 aa)
MXAN_0414Identified by match to protein family HMM PF00149. (379 aa)
MXAN_0420Hypothetical protein; Identified by Glimmer2; putative. (73 aa)
MXAN_0450Identified by match to protein family HMM PF01066; match to protein family HMM PF04138; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (411 aa)
MXAN_0452Putative myo-inositol-1-phosphate synthase; Identified by match to protein family HMM PF01658; match to protein family HMM PF07994. (444 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. (346 aa)
nudCHydrolase, NUDIX family; Identified by match to protein family HMM PF00293; Belongs to the Nudix hydrolase family. NudC subfamily. (277 aa)
MXAN_0496Identified by match to protein family HMM PF00903. (129 aa)
MXAN_0537Putative cardiolipin synthase; Identified by similarity to GB:CAD29690.1; match to protein family HMM PF00614. (486 aa)
MXAN_0564Conserved hypothetical protein; Identified by similarity to GB:BAB49832.1. (392 aa)
MXAN_0604Hypothetical protein; Identified by Glimmer2; putative. (361 aa)
MXAN_0609Identified by match to protein family HMM PF01569. (234 aa)
MXAN_0628Phospholipase domain protein; Identified by match to protein family HMM PF00614. (210 aa)
MXAN_0639Adenylate/guanylate cyclase domain protein; Identified by match to protein family HMM PF00211; match to protein family HMM PF05226. (784 aa)
MXAN_0753Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF00175. (208 aa)
MXAN_0761Thioesterase-like protein; Identified by similarity to GB:AAN67921.1. (270 aa)
MXAN_0788Hypothetical protein; Identified by Glimmer2; putative. (247 aa)
MXAN_0873Adenylate/guanylate cyclase domain protein; Identified by match to protein family HMM PF00211. (199 aa)
MXAN_0888Identified by match to protein family HMM PF00149; match to protein family HMM TIGR01409. (465 aa)
MXAN_0902Acyltransferase domain protein; Identified by match to protein family HMM PF01553. (225 aa)
kmoPutative kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (464 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (426 aa)
nbaC3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (174 aa)
MXAN_0949Identified by match to protein family HMM PF00501. (555 aa)
gnd6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (474 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (223 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (514 aa)
MXAN_0955Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase; Identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (241 aa)
MXAN_1075Phosphoribosyl transferase domain protein; Identified by match to protein family HMM PF00156. (247 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (546 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (478 aa)
pccApropionyl-CoA carboxylase, alpha subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (505 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (513 aa)
MXAN_1273Adenylate and guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. (531 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (220 aa)
gpsANAD-dependent glycerol-3-phosphate dehydrogenase; Identified by similarity to SP:P46919; match to protein family HMM PF01210; match to protein family HMM PF02558; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (335 aa)
MXAN_1362Identified by match to protein family HMM PF00614. (453 aa)
MXAN_1364Conserved hypothetical protein; Similar to the N-terminal domains of SpoT/RelA family proteins; identified by similarity to SP:P17580. (140 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (466 aa)
pssACDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein family HMM TIGR00473; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (287 aa)
MXAN_1438Putative competence/damage-inducible protein CinA; Identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; Belongs to the CinA family. (421 aa)
plsYPutative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (192 aa)
addAdenosine deaminase; Identified by similarity to SP:P22333; match to protein family HMM PF00962; match to protein family HMM TIGR01430. (355 aa)
MXAN_1530HAD-superfamily subfamily IB hydrolase, TIGR01490; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. (221 aa)
MXAN_1596Acyltransferase domain protein; Identified by match to protein family HMM PF01553. (314 aa)
MXAN_1648Conserved hypothetical protein; Identified by similarity to GB:CAD94776.1. (241 aa)
MXAN_1675Hypothetical protein; Identified by Glimmer2; putative; Belongs to the GPAT/DAPAT family. (868 aa)
MXAN_1718Identified by match to protein family HMM PF00903. (117 aa)
MXAN_1828Hypothetical protein; Identified by Glimmer2; putative. (254 aa)
suhBInositol-1-monophosphatase; Identified by similarity to SP:P22783; match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. (273 aa)
MXAN_1944Glycosyl transferase, group 2 family protein; Identified by match to protein family HMM PF00535. (236 aa)
MXAN_1946Acyltransferase domain protein; Identified by match to protein family HMM PF01553. (314 aa)
moaCMolybdenum cofactor biosynthesis protein C; Identified by match to protein family HMM PF01967; match to protein family HMM TIGR00581. (164 aa)
MXAN_1974Conserved hypothetical protein; Identified by similarity to PIR:H75591. (279 aa)
mafMaf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (190 aa)
MXAN_2005Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (197 aa)
MXAN_2022Conserved hypothetical protein; Identified by similarity to SP:Q8P765; match to protein family HMM PF02622; Belongs to the UPF0301 (AlgH) family. (181 aa)
MXAN_2047Hypothetical protein; Identified by Glimmer2; putative. (178 aa)
MXAN_2048Hypothetical protein; Identified by Glimmer2; putative. (196 aa)
MXAN_2054Identified by match to protein family HMM PF01712. (214 aa)
dutdUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (151 aa)
purBAdenylosuccinate lyase; Identified by similarity to SP:P12047; match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (437 aa)
purCPutative phosphoribosylaminoimidazole-succinocarboxamide synthase; Identified by match to protein family HMM PF01259; Belongs to the SAICAR synthetase family. (319 aa)
MXAN_2106Conserved domain protein; Identified by similarity to GB:AAN16882.1. (102 aa)
MXAN_2219Conserved hypothetical protein; Identified by similarity to GB:AAQ94626.1. (184 aa)
MXAN_2224Hypothetical protein; Identified by Glimmer2; putative. (280 aa)
folDMethylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (292 aa)
MXAN_2228Conserved hypothetical protein; Identified by similarity to GB:BAC59994.1. (214 aa)
MXAN_2236Putative 5'-nucleotidase; Identified by similarity to GB:AAD33949.1; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (617 aa)
MXAN_2252Putative arginine kinase; Identified by similarity to SP:P51541; Belongs to the ATP:guanido phosphotransferase family. (341 aa)
thiDPhosphomethylpyrimidine kinase; Identified by match to protein family HMM TIGR00097. (272 aa)
coaAPantothenate kinase; Identified by similarity to SP:P15044; match to protein family HMM PF00485; match to protein family HMM TIGR00554. (317 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1302 aa)
MXAN_2369Putative 3'(2'),5'-bisphosphate nucleotidase; Identified by similarity to SP:P22255; match to protein family HMM PF00459. (277 aa)
MXAN_2418Putative endonuclease. (172 aa)
MXAN_2442ATPase, FliI/YscN family; Identified by similarity to SP:P23445; similarity to SP:P40290; match to protein family HMM PF00006; match to protein family HMM PF02874; match to protein family HMM TIGR01026; match to protein family HMM TIGR02546. (437 aa)
MXAN_2470Identified by match to protein family HMM PF02872. (513 aa)
MXAN_2494Identified by match to protein family HMM PF00903. (288 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (165 aa)
plsXFatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (345 aa)
MXAN_2556Putative phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148; Belongs to the CDS family. (276 aa)
moaDEMolybdopterin converting factor, subunits 1/2; Identified by match to protein family HMM PF02391; match to protein family HMM PF02597; match to protein family HMM TIGR01682. (226 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (658 aa)
cobCAlpha-ribazole-5'-phosphate phosphatase; Identified by similarity to SP:P52086; match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. (209 aa)
tmk-2Putative thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (566 aa)
MXAN_2590Thioesterase domain protein; Identified by match to protein family HMM PF03061. (172 aa)
MXAN_2591Identified by match to protein family HMM PF01712. (213 aa)
nadAQuinolinate synthetase complex, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (310 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (436 aa)
maf-2Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (196 aa)
MXAN_2661Identified by match to protein family HMM PF00149; match to protein family HMM PF02872. (794 aa)
pdhAPyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (389 aa)
pdhCPyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (527 aa)
MXAN_2679HAD-superfamily subfamily IB hydrolase, TIGR01490; Identified by match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. (259 aa)
MXAN_2692Metalloenzyme domain protein; Identified by match to protein family HMM PF01676. (311 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (224 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Identified by similarity to SP:P08178; match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878. (345 aa)
MXAN_2703Putative cAMP phosphodiesterases class-II. (251 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa)
MXAN_2723Adenylate/guanylate cyclase domain protein; Identified by match to protein family HMM PF00211. (843 aa)
moaBMolybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (155 aa)
MXAN_2813Putative diacylglycerol kinase; Identified by match to protein family HMM PF01219. (217 aa)
pgkPhosphoglycerate kinase; Identified by similarity to SP:P40924; match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (395 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (256 aa)
MXAN_2901Putative radical SAM domain protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (202 aa)
pssA-2CDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein family HMM TIGR00473; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (214 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Identified by similarity to SP:P12048; match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. (514 aa)
purDPhosphoribosylamine--glycine ligase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02842; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM TIGR00877; Belongs to the GARS family. (421 aa)
MXAN_2955Putative GTP cyclohydrolase I; Identified by similarity to SP:P19465; match to protein family HMM PF01227. (185 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (198 aa)
pyrDDihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (363 aa)
MXAN_3029Identified by similarity to SP:P22333; match to protein family HMM PF00962. (331 aa)
folD-2Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa)
MXAN_3123Hypothetical protein; Identified by Glimmer2; putative. (350 aa)
MXAN_3191Hypothetical protein; Identified by Glimmer2; putative. (363 aa)
MXAN_3199Conserved hypothetical protein; Identified by similarity to SP:Q58408; match to protein family HMM PF02457. (239 aa)
relAGTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (753 aa)
MXAN_3267Putative thiamine-phosphate pyrophosphorylase; Identified by match to protein family HMM PF02581. (212 aa)
thiGThiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (261 aa)
thiSThiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683. (88 aa)
MXAN_3288Acyltransferase; Identified by match to protein family HMM PF01553; Belongs to the GPAT/DAPAT family. (851 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa)
MXAN_3330Identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (264 aa)
MXAN_3331Identified by match to protein family HMM PF01712. (204 aa)
MXAN_3352Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (346 aa)
MXAN_3383Hypothetical protein; Identified by Glimmer2; putative. (357 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa)
carBCarbamoyl-phosphate synthase, large subunit; Identified by similarity to SP:P38100; match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. (1083 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (221 aa)
MXAN_3437Molybdopterin-binding domain protein; Identified by match to protein family HMM PF00994. (246 aa)
MXAN_34542-oxo acid dehydrogenase acyltransferase catalytic domain protein; Identified by match to protein family HMM PF00198. (288 aa)
pyrBAspartate carbamoyltransferase; Identified by similarity to SP:P56585; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (297 aa)
pyrCDihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (437 aa)
carACarbamoyl-phosphate synthase, small subunit; Identified by similarity to SP:P00907; match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. (374 aa)
pykPyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (466 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (145 aa)
MXAN_3659Identified by match to protein family HMM PF00903. (158 aa)
psdPhosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (280 aa)
MXAN_3743Hypothetical protein; Identified by Glimmer2; putative. (324 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (517 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa)
tesBacyl-CoA thioesterase II; Identified by similarity to SP:P23911; match to protein family HMM PF02551; match to protein family HMM TIGR00189. (289 aa)
MXAN_3927Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. (172 aa)
taFPolyketide TA biosynthesis protein TaF; Identified by similarity to GB:CAB46505.1; match to protein family HMM PF01154. (416 aa)
taCPolyketide TA biosynthesis protein TaC; Identified by similarity to GB:CAB46502.1; match to protein family HMM PF01154. (420 aa)
MXAN_3956Putative adenylate cyclase; Identified by similarity to SP:P40137; match to protein family HMM PF00211; match to protein family HMM PF00498; match to protein family HMM PF01590. (577 aa)
MXAN_3968Conserved domain protein; Identified by similarity to GB:AAM85124.1. (197 aa)
MXAN_3969Identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (263 aa)
MXAN_3975Conserved hypothetical protein; Identified by similarity to GB:AAK24822.1. (255 aa)
pfkA6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (361 aa)
MXAN_4028Putative acyltransferase; Identified by match to protein family HMM PF01553. (573 aa)
cmkCytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. (230 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (322 aa)
MXAN_4044Cytidine and deoxycytidylate deaminase zinc-binding domain protein; Identified by match to protein family HMM PF00383. (150 aa)
MXAN_4067Identified by match to protein family HMM PF02597. (90 aa)
MXAN_4069ThiFdomain/MoeZ/MoeB domain protein; Identified by match to protein family HMM PF00899; match to protein family HMM PF05237. (255 aa)
MXAN_4086Identified by match to protein family HMM PF00149. (398 aa)
coaXPutative transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (256 aa)
udkUridine kinase; Identified by similarity to SP:P31218; match to protein family HMM PF00485; match to protein family HMM TIGR00235. (211 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (190 aa)
MXAN_4188Adenylate/guanylate cyclase domain protein; Identified by match to protein family HMM PF00211. (456 aa)
MXAN_4207Metallophosphoesterase; Identified by match to protein family HMM PF00149. (399 aa)
moeAMolybdopterin biosynthesis MoeA protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (410 aa)
MXAN_4217Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. (416 aa)
MXAN_4223Putative histidinol-phosphate phosphatase; Assignment based on phylogenetic profiling and gene location; identified by match to protein family HMM PF00459; match to protein family HMM TIGR02067. (259 aa)
moaAMolybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (334 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (624 aa)
mvaShydroxymethylglutaryl-CoA synthase; Identified by similarity to GB:AAG02422.1; match to protein family HMM PF01154. (418 aa)
MXAN_4280Hypothetical protein; Identified by Glimmer2; putative. (731 aa)
MXAN_4313Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (532 aa)
MXAN_4341Oxidoreductase alpha (molybdopterin) subunit; Identified by match to protein family HMM PF00384; match to protein family HMM TIGR01701; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (792 aa)
nnrDYjeF-like protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimer [...] (511 aa)
MXAN_4364Identified by match to protein family HMM PF02872. (279 aa)
MXAN_4385beta-alanyl-CoA:ammonia lyase; Identified by similarity to GB:CAG29275.1. (132 aa)
coaBCPhosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (406 aa)
surEAcid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (262 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
nadCNicotinate-nucleotide pyrophosphorylase; Identified by similarity to SP:P30819; match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; Belongs to the NadC/ModD family. (294 aa)
MXAN_4545Tetratricopeptide repeat protein; Identified by similarity to GB:AAS71746.1; match to protein family HMM PF07719. (1420 aa)
MXAN_45642-oxoisovalerate dehydrogenase complex, E1 component, alpha subunit; Identified by similarity to SP:P37940; match to protein family HMM PF00676. (336 aa)
MXAN_4617Glycosyl transferase, group 2 family protein; Identified by match to protein family HMM PF00535. (342 aa)
pgsACDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (201 aa)
nadBL-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (529 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (188 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (583 aa)
MXAN_4683Conserved hypothetical protein TIGR00147; Identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147. (308 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (209 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (397 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (383 aa)
MXAN_4719Glycosyl transferase, group 2 family protein; Identified by match to protein family HMM PF00535. (234 aa)
MXAN_4723Conserved hypothetical protein; Identified by similarity to GB:AAS96838.1; match to protein family HMM PF06230. (268 aa)
lpxAacyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (258 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (153 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (354 aa)
MXAN_4741Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. (396 aa)
plsX-2Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (353 aa)
MXAN_4882Metallophosphoesterase; Identified by match to protein family HMM PF00149. (234 aa)
lpxCUDP-3-O-acyl N-acetylglycosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (314 aa)
mvaDDiphosphomevalonate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01240. (332 aa)
MXAN_5020hydroxymethylglutaryl-CoA reductase; Identified by match to protein family HMM PF00368; match to protein family HMM TIGR00532; Belongs to the HMG-CoA reductase family. (442 aa)
MXAN_5058Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (349 aa)
hptHypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (177 aa)
MXAN_5071Hypothetical protein; Identified by Glimmer2; putative. (271 aa)
tdkThymidine kinase; Identified by match to protein family HMM PF00265. (199 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa)
MXAN_5085Putative phosphomethylpyrimidine kinase. (246 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (218 aa)
MXAN_5109Conserved hypothetical protein. (353 aa)
MXAN_5140Hypothetical protein; Identified by Glimmer2; putative. (312 aa)
MXAN_5163Putative deoxyguanosinetriphosphate triphosphohydrolase; Identified by similarity to SP:P15723; match to protein family HMM TIGR01353. (472 aa)
MXAN_5232Pseudouridine synthase, RluA family; Identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005. (303 aa)
MXAN_5238Conserved hypothetical protein; Identified by similarity to SP:Q9KBN7; match to protein family HMM PF04229. (199 aa)
MXAN_5282Hypothetical protein; Identified by Glimmer2; putative. (118 aa)
MXAN_5325Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (595 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (250 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (184 aa)
coaD-2Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (166 aa)
MXAN_5361Putative 5`-nucleotidase; Identified by similarity to GB:AAM97494.1; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (536 aa)
nadKPutative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (305 aa)
MXAN_5370Putative lipoprotein. (377 aa)
rpiARibose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (236 aa)
MXAN_5527Identified by match to protein family HMM PF00903. (159 aa)
gpmAPutative 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (202 aa)
MXAN_5575Conserved hypothetical protein; Identified by similarity to PIR:D70933. (481 aa)
MXAN_5578Identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (245 aa)
MXAN_5585Identified by match to protein family HMM PF02366. (727 aa)
MXAN_5689Putative lipoprotein. (520 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (227 aa)
MXAN_5761Acyltransferase domain protein; Identified by match to protein family HMM PF01553. (439 aa)
accC-3acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (461 aa)
ribFRiboflavin biosynthesis protein RibF; Identified by similarity to SP:Q59263; match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; Belongs to the ribF family. (308 aa)
acsA-2acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Identified by similarity to SP:Q9P9M3; match to protein family HMM PF00215; match to protein family HMM TIGR02127; Belongs to the OMP decarboxylase family. Type 2 subfamily. (288 aa)
talPutative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (223 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (267 aa)
MXAN_5950HD domain protein; Identified by match to protein family HMM PF01966. (431 aa)
sucB2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (398 aa)
MXAN_6070Identified by match to protein family HMM PF00300. (201 aa)
MXAN_6110Conserved hypothetical protein; Identified by similarity to GB:AAM37733.1. (194 aa)
MXAN_6147Hypothetical protein; Identified by Glimmer2; putative. (1166 aa)
MXAN_6252Identified by match to protein family HMM PF00903. (142 aa)
MXAN_6266Putative 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Identified by similarity to SP:P08331; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (602 aa)
MXAN_6270Hypothetical protein; Identified by Glimmer2; putative. (660 aa)
pyk-2Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (477 aa)
MXAN_6319Identified by match to protein family HMM PF00614. (377 aa)
pfkA-26-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (345 aa)
MXAN_6383Identified by match to protein family HMM PF00149. (426 aa)
fabZ-2Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (160 aa)
MXAN_6397Putative (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase; Identified by similarity to SP:P21774; match to protein family HMM PF07977. (163 aa)
MXAN_6408Identified by match to protein family HMM PF00614; match to protein family HMM PF01833. (1340 aa)
MXAN_6430Hypothetical protein; Identified by Glimmer2; putative. (65 aa)
MXAN_6431Cardiolipin synthetase domain protein; Identified by similarity to SP:P31071. (269 aa)
MXAN_6495Identified by match to protein family HMM PF00903. (219 aa)
MXAN_6513Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. (197 aa)
MXAN_6543Identified by match to protein family HMM PF00149. (336 aa)
MXAN_6690Circadian phase modifier CpmA-like protein; Identified by similarity to GB:AAD29318.1. (250 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (315 aa)
MXAN_6707Identified by match to protein family HMM PF00903. (129 aa)
MXAN_6724Conserved hypothetical protein TIGR00147; Identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147. (304 aa)
MXAN_67432-oxo acid dehydrogenases acyltransferase domain protein; Identified by similarity to SP:O31550; match to protein family HMM PF00198. (341 aa)
MXAN_6753Identified by match to protein family HMM PF00614. (553 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (496 aa)
nadEPutative glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (630 aa)
pgiGlucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342. (529 aa)
atpCATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (136 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (481 aa)
atpGATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (294 aa)
MXAN_6972Identified by match to protein family HMM PF00149. (300 aa)
atpHATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (182 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (552 aa)
MXAN_7138Competence/damage-inducible protein CinA domain protein; Identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199; Belongs to the CinA family. (174 aa)
MXAN_7156Putative ribose-phosphate pyrophosphokinase; Identified by similarity to SP:P14193; match to protein family HMM PF00156; match to protein family HMM TIGR01251; Belongs to the ribose-phosphate pyrophosphokinase family. (301 aa)
MXAN_7166Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (448 aa)
MXAN_7193Hypothetical protein; Identified by Glimmer2; putative. (342 aa)
MXAN_7243Conserved hypothetical protein. (256 aa)
MXAN_7285Identified by match to protein family HMM PF00899. (598 aa)
MXAN_7302Identified by match to protein family HMM PF01066; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (200 aa)
glpDGlycerol-3-phosphate dehydrogenase; Identified by similarity to SP:P18158; match to protein family HMM PF01266; match to protein family HMM PF01494; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (565 aa)
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (687 aa)
MXAN_7396Response regulator/adenylate cyclase; Identified by similarity to SP:P40138; match to protein family HMM PF00072; match to protein family HMM PF00211. (497 aa)
MXAN_7403Hypothetical protein; Identified by Glimmer2; putative. (335 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (208 aa)
moeA-2Molybdopterin biosynthesis MoeA protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (416 aa)
mobB/FdhDSulfur carrier protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (466 aa)
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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