18 items (Myxococcus xanthus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	frzS	Response regulator FrzS; Identified by similarity to GB:AAC98490.1; match to protein family HMM PF00072. (562 aa)
	MXAN_5764	Conserved hypothetical protein; Identified by similarity to GB:CAE80296.1; match to protein family HMM PF04357. (1294 aa)
	MXAN_5765	Putative general secretion pathway protein A; Identified by similarity to SP:P45754. (314 aa)
	MXAN_5766	TPR domain protein; Identified by match to protein family HMM PF00515. (1060 aa)
	pilQ	Type IV pilus secretin PilQ; Identified by similarity to GB:AAD04923.1; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515. (901 aa)
	pilM	Type IV pilus biogenesis protein PilM; Identified by similarity to PIR:S77726; match to protein family HMM TIGR01175. (395 aa)
	pilA	Pilin; Makes up the pili which are long filamentous (less than 10 nm thick and up to 10 um long) polarly located appendages. They are required for social (S) motility; Belongs to the N-Me-Phe pilin family. (220 aa)
	aglZ	Adventurous gliding motility protein AglZ; Required for adventurous-gliding motility (A motility), in response to environmental signals sensed by the frz chemosensory system. Forms ordered clusters that span the cell length and that remain stationary relative to the surface across which the cells move, serving as anchor points (focal, transient adhesion sites) that allow the bacterium to move forward. Clusters disassemble at the lagging cell pole. (1395 aa)
	pilT-3	Twitching motility protein PilT; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420. (372 aa)
	pilB	Type IV-A pilus assembly ATPase PilB; Identified by match to protein family HMM PF00437; match to protein family HMM PF05157; match to protein family HMM TIGR02538. (566 aa)
	pilT-4	Twitching motility protein PilT; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420. (369 aa)
	pilC	Type 4 fimbrial assembly protein PilC; Identified by similarity to GB:AAA25733.1; similarity to GB:AAT00616.1; match to protein family HMM PF00482. (417 aa)
	cglB	Adventurous gliding motility protein CglB; Identified by similarity to GB:AAB86642.1. (416 aa)
	divIVA	Cell-division initiation protein DivIVA; Identified by similarity to GB:CAB06818.1; match to protein family HMM PF05103. (175 aa)
	pilT	Twitching mobility protein; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420. (364 aa)
	mglA	Gliding motility protein MglA; Required for multicellular development and for both mechanisms of gliding: social (S) and adventurous (A) motility. Acts as an intracellular switch to coordinate A and S motilities. Controls the direction of gliding and gliding speed; Belongs to the small GTPase superfamily. Arf family. MglA subfamily. (195 aa)
	mglB	Gliding motility protein MglB; Identified by similarity to GB:AAA25388.2; match to protein family HMM PF03259. (159 aa)
	pilT-2	Twitching mobility protein; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420. (491 aa)

Your Current Organism:

Myxococcus xanthus

NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MXAN_5764	MXAN_5765	MXAN_5764	MXAN_5765	Conserved hypothetical protein; Identified by similarity to GB:CAE80296.1; match to protein family HMM PF04357.	Putative general secretion pathway protein A; Identified by similarity to SP:P45754.	0.939
MXAN_5764	MXAN_5766	MXAN_5764	MXAN_5766	Conserved hypothetical protein; Identified by similarity to GB:CAE80296.1; match to protein family HMM PF04357.	TPR domain protein; Identified by match to protein family HMM PF00515.	0.958
MXAN_5764	aglZ	MXAN_5764	MXAN_2991	Conserved hypothetical protein; Identified by similarity to GB:CAE80296.1; match to protein family HMM PF04357.	Adventurous gliding motility protein AglZ; Required for adventurous-gliding motility (A motility), in response to environmental signals sensed by the frz chemosensory system. Forms ordered clusters that span the cell length and that remain stationary relative to the surface across which the cells move, serving as anchor points (focal, transient adhesion sites) that allow the bacterium to move forward. Clusters disassemble at the lagging cell pole.	0.717
MXAN_5765	MXAN_5764	MXAN_5765	MXAN_5764	Putative general secretion pathway protein A; Identified by similarity to SP:P45754.	Conserved hypothetical protein; Identified by similarity to GB:CAE80296.1; match to protein family HMM PF04357.	0.939
MXAN_5765	MXAN_5766	MXAN_5765	MXAN_5766	Putative general secretion pathway protein A; Identified by similarity to SP:P45754.	TPR domain protein; Identified by match to protein family HMM PF00515.	0.958
MXAN_5765	pilM	MXAN_5765	MXAN_5776	Putative general secretion pathway protein A; Identified by similarity to SP:P45754.	Type IV pilus biogenesis protein PilM; Identified by similarity to PIR:S77726; match to protein family HMM TIGR01175.	0.535
MXAN_5765	pilQ	MXAN_5765	MXAN_5772	Putative general secretion pathway protein A; Identified by similarity to SP:P45754.	Type IV pilus secretin PilQ; Identified by similarity to GB:AAD04923.1; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515.	0.523
MXAN_5766	MXAN_5764	MXAN_5766	MXAN_5764	TPR domain protein; Identified by match to protein family HMM PF00515.	Conserved hypothetical protein; Identified by similarity to GB:CAE80296.1; match to protein family HMM PF04357.	0.958
MXAN_5766	MXAN_5765	MXAN_5766	MXAN_5765	TPR domain protein; Identified by match to protein family HMM PF00515.	Putative general secretion pathway protein A; Identified by similarity to SP:P45754.	0.958
MXAN_5766	aglZ	MXAN_5766	MXAN_2991	TPR domain protein; Identified by match to protein family HMM PF00515.	Adventurous gliding motility protein AglZ; Required for adventurous-gliding motility (A motility), in response to environmental signals sensed by the frz chemosensory system. Forms ordered clusters that span the cell length and that remain stationary relative to the surface across which the cells move, serving as anchor points (focal, transient adhesion sites) that allow the bacterium to move forward. Clusters disassemble at the lagging cell pole.	0.408
MXAN_5766	mglA	MXAN_5766	MXAN_1925	TPR domain protein; Identified by match to protein family HMM PF00515.	Gliding motility protein MglA; Required for multicellular development and for both mechanisms of gliding: social (S) and adventurous (A) motility. Acts as an intracellular switch to coordinate A and S motilities. Controls the direction of gliding and gliding speed; Belongs to the small GTPase superfamily. Arf family. MglA subfamily.	0.742
MXAN_5766	mglB	MXAN_5766	MXAN_1926	TPR domain protein; Identified by match to protein family HMM PF00515.	Gliding motility protein MglB; Identified by similarity to GB:AAA25388.2; match to protein family HMM PF03259.	0.755
MXAN_5766	pilM	MXAN_5766	MXAN_5776	TPR domain protein; Identified by match to protein family HMM PF00515.	Type IV pilus biogenesis protein PilM; Identified by similarity to PIR:S77726; match to protein family HMM TIGR01175.	0.518
MXAN_5766	pilQ	MXAN_5766	MXAN_5772	TPR domain protein; Identified by match to protein family HMM PF00515.	Type IV pilus secretin PilQ; Identified by similarity to GB:AAD04923.1; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515.	0.614
aglZ	MXAN_5764	MXAN_2991	MXAN_5764	Adventurous gliding motility protein AglZ; Required for adventurous-gliding motility (A motility), in response to environmental signals sensed by the frz chemosensory system. Forms ordered clusters that span the cell length and that remain stationary relative to the surface across which the cells move, serving as anchor points (focal, transient adhesion sites) that allow the bacterium to move forward. Clusters disassemble at the lagging cell pole.	Conserved hypothetical protein; Identified by similarity to GB:CAE80296.1; match to protein family HMM PF04357.	0.717
aglZ	MXAN_5766	MXAN_2991	MXAN_5766	Adventurous gliding motility protein AglZ; Required for adventurous-gliding motility (A motility), in response to environmental signals sensed by the frz chemosensory system. Forms ordered clusters that span the cell length and that remain stationary relative to the surface across which the cells move, serving as anchor points (focal, transient adhesion sites) that allow the bacterium to move forward. Clusters disassemble at the lagging cell pole.	TPR domain protein; Identified by match to protein family HMM PF00515.	0.408
aglZ	cglB	MXAN_2991	MXAN_3060	Adventurous gliding motility protein AglZ; Required for adventurous-gliding motility (A motility), in response to environmental signals sensed by the frz chemosensory system. Forms ordered clusters that span the cell length and that remain stationary relative to the surface across which the cells move, serving as anchor points (focal, transient adhesion sites) that allow the bacterium to move forward. Clusters disassemble at the lagging cell pole.	Adventurous gliding motility protein CglB; Identified by similarity to GB:AAB86642.1.	0.597
aglZ	frzS	MXAN_2991	MXAN_4149	Adventurous gliding motility protein AglZ; Required for adventurous-gliding motility (A motility), in response to environmental signals sensed by the frz chemosensory system. Forms ordered clusters that span the cell length and that remain stationary relative to the surface across which the cells move, serving as anchor points (focal, transient adhesion sites) that allow the bacterium to move forward. Clusters disassemble at the lagging cell pole.	Response regulator FrzS; Identified by similarity to GB:AAC98490.1; match to protein family HMM PF00072.	0.510
aglZ	mglA	MXAN_2991	MXAN_1925	Adventurous gliding motility protein AglZ; Required for adventurous-gliding motility (A motility), in response to environmental signals sensed by the frz chemosensory system. Forms ordered clusters that span the cell length and that remain stationary relative to the surface across which the cells move, serving as anchor points (focal, transient adhesion sites) that allow the bacterium to move forward. Clusters disassemble at the lagging cell pole.	Gliding motility protein MglA; Required for multicellular development and for both mechanisms of gliding: social (S) and adventurous (A) motility. Acts as an intracellular switch to coordinate A and S motilities. Controls the direction of gliding and gliding speed; Belongs to the small GTPase superfamily. Arf family. MglA subfamily.	0.955
aglZ	mglB	MXAN_2991	MXAN_1926	Adventurous gliding motility protein AglZ; Required for adventurous-gliding motility (A motility), in response to environmental signals sensed by the frz chemosensory system. Forms ordered clusters that span the cell length and that remain stationary relative to the surface across which the cells move, serving as anchor points (focal, transient adhesion sites) that allow the bacterium to move forward. Clusters disassemble at the lagging cell pole.	Gliding motility protein MglB; Identified by similarity to GB:AAA25388.2; match to protein family HMM PF03259.	0.660