15 items (Myxococcus xanthus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pilT-4	Twitching motility protein PilT; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420. (369 aa)
	pilT	Twitching mobility protein; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420. (364 aa)
	recA	recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (363 aa)
	recA-2	recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (342 aa)
	pilT-2	Twitching mobility protein; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420. (491 aa)
	gspF	General secretion pathway protein F; Identified by similarity to GB:AAD05175.1; match to protein family HMM PF00482; match to protein family HMM TIGR02120. (418 aa)
	gspE	General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (605 aa)
	comE	comE protein; Identified by similarity to GB:AAG18336.1; match to protein family HMM PF00633. (138 aa)
	pilQ	Type IV pilus secretin PilQ; Identified by similarity to GB:AAD04923.1; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515. (901 aa)
	pilO	Type IV pilus biogenesis protein PilO; Identified by similarity to GB:AAA87404.1. (205 aa)
	pilN	Type IV pilus biogenesis protein PilN; Identified by similarity to GB:AAA87403.1; match to protein family HMM PF05137. (225 aa)
	pilM	Type IV pilus biogenesis protein PilM; Identified by similarity to PIR:S77726; match to protein family HMM TIGR01175. (395 aa)
	gspO	Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (335 aa)
	pilT-3	Twitching motility protein PilT; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420. (372 aa)
	pilB	Type IV-A pilus assembly ATPase PilB; Identified by match to protein family HMM PF00437; match to protein family HMM PF05157; match to protein family HMM TIGR02538. (566 aa)

Your Current Organism:

Myxococcus xanthus

NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
comE	gspF	MXAN_3467	MXAN_2512	comE protein; Identified by similarity to GB:AAG18336.1; match to protein family HMM PF00633.	General secretion pathway protein F; Identified by similarity to GB:AAD05175.1; match to protein family HMM PF00482; match to protein family HMM TIGR02120.	0.608
comE	gspO	MXAN_3467	MXAN_5779	comE protein; Identified by similarity to GB:AAG18336.1; match to protein family HMM PF00633.	Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.546
gspE	gspF	MXAN_2513	MXAN_2512	General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	General secretion pathway protein F; Identified by similarity to GB:AAD05175.1; match to protein family HMM PF00482; match to protein family HMM TIGR02120.	0.993
gspE	gspO	MXAN_2513	MXAN_5779	General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.927
gspE	pilM	MXAN_2513	MXAN_5776	General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	Type IV pilus biogenesis protein PilM; Identified by similarity to PIR:S77726; match to protein family HMM TIGR01175.	0.624
gspE	pilN	MXAN_2513	MXAN_5775	General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	Type IV pilus biogenesis protein PilN; Identified by similarity to GB:AAA87403.1; match to protein family HMM PF05137.	0.577
gspE	pilO	MXAN_2513	MXAN_5774	General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	Type IV pilus biogenesis protein PilO; Identified by similarity to GB:AAA87404.1.	0.418
gspE	pilQ	MXAN_2513	MXAN_5772	General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	Type IV pilus secretin PilQ; Identified by similarity to GB:AAD04923.1; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515.	0.570
gspE	pilT	MXAN_2513	MXAN_0415	General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	Twitching mobility protein; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420.	0.465
gspE	pilT-2	MXAN_2513	MXAN_1995	General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	Twitching mobility protein; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420.	0.494
gspE	pilT-3	MXAN_2513	MXAN_5787	General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	Twitching motility protein PilT; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420.	0.483
gspE	pilT-4	MXAN_2513	MXAN_6706	General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	Twitching motility protein PilT; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420.	0.482
gspF	comE	MXAN_2512	MXAN_3467	General secretion pathway protein F; Identified by similarity to GB:AAD05175.1; match to protein family HMM PF00482; match to protein family HMM TIGR02120.	comE protein; Identified by similarity to GB:AAG18336.1; match to protein family HMM PF00633.	0.608
gspF	gspE	MXAN_2512	MXAN_2513	General secretion pathway protein F; Identified by similarity to GB:AAD05175.1; match to protein family HMM PF00482; match to protein family HMM TIGR02120.	General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	0.993
gspF	gspO	MXAN_2512	MXAN_5779	General secretion pathway protein F; Identified by similarity to GB:AAD05175.1; match to protein family HMM PF00482; match to protein family HMM TIGR02120.	Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.902
gspF	pilB	MXAN_2512	MXAN_5788	General secretion pathway protein F; Identified by similarity to GB:AAD05175.1; match to protein family HMM PF00482; match to protein family HMM TIGR02120.	Type IV-A pilus assembly ATPase PilB; Identified by match to protein family HMM PF00437; match to protein family HMM PF05157; match to protein family HMM TIGR02538.	0.904
gspF	pilM	MXAN_2512	MXAN_5776	General secretion pathway protein F; Identified by similarity to GB:AAD05175.1; match to protein family HMM PF00482; match to protein family HMM TIGR02120.	Type IV pilus biogenesis protein PilM; Identified by similarity to PIR:S77726; match to protein family HMM TIGR01175.	0.684
gspF	pilN	MXAN_2512	MXAN_5775	General secretion pathway protein F; Identified by similarity to GB:AAD05175.1; match to protein family HMM PF00482; match to protein family HMM TIGR02120.	Type IV pilus biogenesis protein PilN; Identified by similarity to GB:AAA87403.1; match to protein family HMM PF05137.	0.446
gspF	pilO	MXAN_2512	MXAN_5774	General secretion pathway protein F; Identified by similarity to GB:AAD05175.1; match to protein family HMM PF00482; match to protein family HMM TIGR02120.	Type IV pilus biogenesis protein PilO; Identified by similarity to GB:AAA87404.1.	0.453
gspF	pilQ	MXAN_2512	MXAN_5772	General secretion pathway protein F; Identified by similarity to GB:AAD05175.1; match to protein family HMM PF00482; match to protein family HMM TIGR02120.	Type IV pilus secretin PilQ; Identified by similarity to GB:AAD04923.1; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515.	0.594