STRINGSTRING
SPO1683 SPO1683 tsaD tsaD SPO3848 SPO3848 SPO3750 SPO3750 SPO3722 SPO3722 SPO3681 SPO3681 SPO3678 SPO3678 bioB bioB SPO3021 SPO3021 SPO3019 SPO3019 SPO2881 SPO2881 nuoB nuoB nuoI nuoI SPO2748 SPO2748 SPO2694 SPO2694 ispG ispG SPO2438 SPO2438 SPO2415 SPO2415 coxL-2 coxL-2 hutI hutI cycF cycF SPO1898 SPO1898 SPO1796 SPO1796 SPO0764 SPO0764 SPO0819 SPO0819 SPO0830 SPO0830 SPO1393 SPO1393 SPO1451 SPO1451 pqqE pqqE coxL-1 coxL-1 SPO1590 SPO1590 SPO1622 SPO1622 nbaC nbaC SPO0226 SPO0226 SPO0328 SPO0328 SPO0382 SPO0382 SPO0432 SPO0432 SPO0525 SPO0525 SPO0619 SPO0619 xdhB xdhB xdhA xdhA hmgA hmgA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPO1683Hypothetical protein; Identified by similarity to GB:AAK22449.1. (150 aa)
tsaDO-sialoglycoprotein endopeptidase, putative; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (365 aa)
SPO3848Sterol desaturase family protein; Identified by similarity to GB:BAC09469.1; match to protein family HMM PF01598. (260 aa)
SPO3750Hypothetical protein; Identified by similarity to GB:CAC47108.1. (339 aa)
SPO3722Identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738. (172 aa)
SPO3681Rieske 2Fe-2S domain protein; Identified by match to protein family HMM PF00355. (380 aa)
SPO3678Rieske 2Fe-2S domain protein; Identified by match to protein family HMM PF00355. (369 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (318 aa)
SPO3021Identified by match to protein family HMM PF05721. (322 aa)
SPO3019Xanthine dehydrogenase family protein, large subunit; Identified by match to protein family HMM PF01315; match to protein family HMM PF02738. (763 aa)
SPO2881Xanthine dehydrogenase family protein, large subunit; Identified by match to protein family HMM PF01315; match to protein family HMM PF02738. (731 aa)
nuoBNADH dehydrogenase I, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (177 aa)
nuoINADH dehydrogenase I, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (164 aa)
SPO2748Hypothetical protein; Identified by similarity to PIR:AG2090. (195 aa)
SPO2694Identified by match to protein family HMM PF01322. (147 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (375 aa)
SPO2438Identified by match to protein family HMM PF05721. (295 aa)
SPO2415Identified by match to protein family HMM PF05721. (304 aa)
coxL-2Carbon monoxide dehydrogenase, large subunit; Identified by similarity to SP:P19919; match to protein family HMM PF01315; match to protein family HMM PF02738. (809 aa)
hutIImidazolonepropionase; Identified by match to protein family HMM PF01979; match to protein family HMM TIGR01224; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (435 aa)
cycFCytochrome c-554; Identified by similarity to SP:Q53142; match to protein family HMM PF01322. (158 aa)
SPO1898Identified by match to protein family HMM PF00067. (450 aa)
SPO1796Formate dehydrogenase, alpha subunit, putative; Identified by similarity to PIR:S18213; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (964 aa)
SPO0764Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (419 aa)
SPO0819Amidohydrolase domain protein; Identified by match to protein family HMM PF01979. (388 aa)
SPO0830Xanthine dehydrogenase family protein, small/large subunits; Identified by match to protein family HMM PF00111; match to protein family HMM PF01315; match to protein family HMM PF01799; match to protein family HMM PF02738. (915 aa)
SPO1393Identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738. (164 aa)
SPO1451Aromatic 1,2-dioxygenase, alpha subunit; Identified by match to protein family HMM PF00355; match to protein family HMM PF00848. (441 aa)
pqqECoenzyme PQQ synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (374 aa)
coxL-1Carbon monoxide dehydrogenase, large subunit; Identified by similarity to SP:P19913; match to protein family HMM PF01315; match to protein family HMM PF02738. (788 aa)
SPO1590Rieske 2Fe-2S domain protein; Identified by match to protein family HMM PF00355. (363 aa)
SPO1622Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family. (430 aa)
nbaC3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (180 aa)
SPO0226Cytochrome P450 family protein. (412 aa)
SPO0328Hypothetical protein; Identified by similarity to GB:BAB48523.1. (310 aa)
SPO0382nifU domain protein; Identified by match to protein family HMM PF01106. (187 aa)
SPO0432Identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738. (148 aa)
SPO0525Sterol desaturase-like protein. (264 aa)
SPO0619Sterol desaturase family protein. (398 aa)
xdhBXanthine dehydrogenase, B subunit; Identified by similarity to GB:CAA04470.2. (776 aa)
xdhAXanthine dehydrogenase, A subunit; Identified by similarity to GB:CAA04469.1. (461 aa)
hmgAHomogentisate 1,2-dioxygenase; Identified by similarity to SP:Q9X4F5. (451 aa)
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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