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| | SPO1343 | Identified by match to protein family HMM PF00043; match to protein family HMM PF02798. (213 aa) |
| | SPO3896 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (203 aa) |
| | SPO3841 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (205 aa) |
| | folC | folC bifunctional protein; Identified by match to protein family HMM PF01225; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family. (424 aa) |
| | SPO3764 | Identified by match to protein family HMM PF02798. (221 aa) |
| | SPO3681 | Rieske 2Fe-2S domain protein; Identified by match to protein family HMM PF00355. (380 aa) |
| | SPO3678 | Rieske 2Fe-2S domain protein; Identified by match to protein family HMM PF00355. (369 aa) |
| | gshA | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (456 aa) |
| | SPO3545 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (185 aa) |
| | glyA-3 | Serine hydroxymethyltransferase; Identified by match to protein family HMM PF00464. (431 aa) |
| | SPO3494 | Identified by match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily. (233 aa) |
| | SPO3486 | Hypothetical protein; Identified by similarity to PIR:B83165. (232 aa) |
| | SPO3435 | Identified by match to protein family HMM PF00043; match to protein family HMM PF02798. (197 aa) |
| | SPO3411 | Gamma-glutamyltranspeptidase, putative; Identified by match to protein family HMM PF01019. (525 aa) |
| | SPO3388 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (207 aa) |
| | SPO3368 | Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (777 aa) |
| | gabD-2 | Succinate-semialdehyde dehydrogenase; Identified by similarity to SP:P25526; match to protein family HMM PF00171; match to protein family HMM TIGR01780; Belongs to the aldehyde dehydrogenase family. (503 aa) |
| | SPO3306 | Glutathione S-transferase, putative; Identified by similarity to GB:AAC44159.1; match to protein family HMM PF00043; match to protein family HMM PF02798. (204 aa) |
| | SPO3299 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (194 aa) |
| | SPO3261 | Identified by match to protein family HMM PF00043; match to protein family HMM PF02798. (222 aa) |
| | SPO3222 | Hypothetical protein; Identified by similarity to PIR:T45023. (329 aa) |
| | SPO3208 | Identified by match to protein family HMM PF00043. (209 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. (188 aa) |
| | SPO3191 | Identified by match to protein family HMM PF00171. (483 aa) |
| | SPO3173 | Cation transport protein ChaC, putative; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (177 aa) |
| | fhs-2 | Formate--tetrahydrofolate ligase; Identified by similarity to SP:Q59925; match to protein family HMM PF01268. (558 aa) |
| | SPO3101 | folD bifunctional protein; Identified by similarity to SP:P54382; match to protein family HMM PF00763; match to protein family HMM PF02882. (296 aa) |
| | SPO3080 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (193 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase; Identified by similarity to SP:P00394; match to protein family HMM PF02219; match to protein family HMM TIGR00676; Belongs to the methylenetetrahydrofolate reductase family. (307 aa) |
| | SPO2954 | Identified by match to protein family HMM PF01812; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (185 aa) |
| | glyA-2 | Serine hydroxymethyltransferase; Identified by similarity to SP:P50435; match to protein family HMM PF00464. (431 aa) |
| | SPO2917 | Identified by match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily. (212 aa) |
| | SPO2905 | Hypothetical protein; Identified by similarity to GB:CAC45122.1; match to protein family HMM PF06108. (112 aa) |
| | SPO2902 | Identified by match to protein family HMM PF00043; match to protein family HMM PF02798. (209 aa) |
| | SPO2708 | Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (493 aa) |
| | SPO2705 | Identified by match to protein family HMM PF00725; match to protein family HMM PF02737. (317 aa) |
| | SPO2703 | Hypothetical protein; Identified by similarity to PIR:G82972; match to protein family HMM PF05853. (296 aa) |
| | SPO2576 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (205 aa) |
| | iseJ | Isethionate dehydrogenase; Identified by match to protein family HMM PF00732; match to protein family HMM PF05199; PMID: 19933343. (535 aa) |
| | SPO2346 | Sarcosine oxidase, delta subunit family; Identified by similarity to SP:Q46336; match to protein family HMM PF04267. (109 aa) |
| | SPO2345 | Sarcosine oxidase, alpha subunit family; Identified by similarity to SP:Q46337; match to protein family HMM PF01571; match to protein family HMM TIGR01372; Belongs to the GcvT family. (1010 aa) |
| | SPO2344 | Sarcosine oxidase, gamma subunit family; Identified by similarity to SP:Q46338; match to protein family HMM PF04268. (188 aa) |
| | SPO2209 | Glutamate--cysteine ligase family protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (384 aa) |
| | SPO2163 | Hypothetical protein; Identified by similarity to PIR:AC3193. (209 aa) |
| | SPO2059 | Identified by match to protein family HMM PF02798. (280 aa) |
| | SPO2004 | Hypothetical protein; Identified by similarity to GB:BAB47761.1; match to protein family HMM PF05853. (308 aa) |
| | SPO1946 | Identified by match to protein family HMM PF00132. (174 aa) |
| | SPO1902 | Transcription regulator, TetR family; Identified by match to protein family HMM PF00440. (191 aa) |
| | SPO1862 | metFprotein-like protein; Identified by similarity to PIR:B97532. (309 aa) |
| | SPO1853 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (213 aa) |
| | SPO1780 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (205 aa) |
| | SPO1747 | Sarcosine oxidase, gamma subunit family; Identified by match to protein family HMM PF04268. (189 aa) |
| | SPO1746 | Sarcosine oxidase, alpha subunit family; Identified by similarity to SP:Q46337; match to protein family HMM PF01571; match to protein family HMM TIGR01372; Belongs to the GcvT family. (977 aa) |
| | SPO1745 | Sarcosine oxidase, delta subunit family; Identified by similarity to SP:Q46336; match to protein family HMM PF04267. (87 aa) |
| | SPO1736 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (194 aa) |
| | panE-2 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (311 aa) |
| | SPO1590 | Rieske 2Fe-2S domain protein; Identified by match to protein family HMM PF00355. (363 aa) |
| | SPO1587 | Sarcosine oxidase, delta subunit family; Identified by similarity to SP:Q46336; match to protein family HMM PF04267. (95 aa) |
| | SPO1586 | Sarcosine oxidase, alpha subunit family; Identified by similarity to SP:Q46337; match to protein family HMM PF01571; match to protein family HMM TIGR01372; Belongs to the GcvT family. (983 aa) |
| | SPO1585 | Sarcosine oxidase, gamma subunit family; Identified by match to protein family HMM PF04268; match to protein family HMM TIGR01375. (186 aa) |
| | glyA-1 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa) |
| | folD | folD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (292 aa) |
| | folD1 | folD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (296 aa) |
| | fhs-1 | Formate--tetrahydrofolate ligase; Identified by similarity to SP:Q59925; match to protein family HMM PF01268; Belongs to the formate--tetrahydrofolate ligase family. (558 aa) |
| | SPO1484 | Hypothetical protein; Identified by similarity to GB:AAO56021.1. (164 aa) |
| | SPO1467 | Identified by match to protein family HMM PF00725; match to protein family HMM PF02737. (327 aa) |
| | lcdH | 3-hydroxyacyl-CoA dehydrogenase family protein; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. (487 aa) |
| | SPO1435 | Identified by match to protein family HMM PF05853. (301 aa) |
| | SPO1400 | Identified by match to protein family HMM PF05853. (252 aa) |
| | folP | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (264 aa) |
| | SPO1362 | Dihydroneopterin aldolase, putative; Identified by match to protein family HMM TIGR00526. (306 aa) |
| | SPO1324 | Identified by match to protein family HMM PF02798. (233 aa) |
| | SPO1257 | Identified by match to protein family HMM PF02798; Belongs to the GST superfamily. (203 aa) |
| | gst | Glutathione S-transferase; Identified by similarity to SP:P39100; match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily. (204 aa) |
| | doeC | Aspartate-semialdehyde dehydrogenase; Identified by similarity to SP:P25526; match to protein family HMM PF00171; match to protein family HMM TIGR01780. (491 aa) |
| | betA | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (552 aa) |
| | betI-2 | Transcriptional regulator, TetR family; Repressor involved in choline regulation of the bet genes. (193 aa) |
| | betI | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. (192 aa) |
| | SPO1030 | Identified by match to protein family HMM PF00753. (305 aa) |
| | SPO1027 | Putative protein TIGR01244; Identified by similarity to PIR:T10511; match to protein family HMM PF04273; match to protein family HMM TIGR01244. (143 aa) |
| | SPO0971 | Oxidoreductase, GMC family; Identified by match to protein family HMM PF00732; match to protein family HMM PF05199. (534 aa) |
| | panE-1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (331 aa) |
| | SPO0953 | Hypothetical protein; Identified by similarity to GB:BAB49280.1. (292 aa) |
| | SPO0866 | Gamma-glutamyltranspeptidase, putative; Identified by match to protein family HMM PF01019. (596 aa) |
| | SPO0836 | Hypothetical protein; Identified by similarity to GB:BAB48851.1. (171 aa) |
| | SPO0799 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (220 aa) |
| | SPO0743 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (198 aa) |
| | hmgC | Maleylacetoacetate isomerase; Identified by similarity to SP:O43708. (213 aa) |
| | ggt | Gamma-glutamyltranspeptidase; Identified by similarity to SP:P54422. (597 aa) |
| | SPO0606 | Hypothetical protein; Identified by similarity to PIR:C95874. (562 aa) |
| | SPO0576 | Transcriptional regulator, TetR family; Identified by similarity to GB:AAS05297.1. (209 aa) |
| | SPO0563 | Glutathione S-transferase, putative; Identified by similarity to SP:Q12390. (209 aa) |
| | SPO0431 | Hypothetical protein; Identified by similarity to PIR:E82090. (189 aa) |
| | SPO0403 | Hypothetical protein; Identified by similarity to GB:CAD13614.1. (291 aa) |
| | gshB | Glutathione synthetase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family. (310 aa) |
| | SPO0270 | Identified by match to protein family HMM PF02798. (203 aa) |
| | aasadh | Alpha-aminoadipic semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (504 aa) |
| | SPO0190 | Oxidoreductase, GMC family; Identified by match to protein family HMM PF00732; match to protein family HMM PF05199. (537 aa) |
| | SPO0153 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (195 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (285 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (279 aa) |
| | SPO0097 | Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (483 aa) |
| | betB | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. (484 aa) |
