STRINGSTRING
SPO0971 SPO0971 betB betB SPO0097 SPO0097 panB panB panC panC SPO0153 SPO0153 SPO0190 SPO0190 aasadh aasadh gshB gshB SPO0576 SPO0576 ggt ggt SPO0743 SPO0743 SPO0799 SPO0799 SPO0866 SPO0866 panE-1 panE-1 betI betI betI-2 betI-2 betA betA doeC doeC folP folP SPO1484 SPO1484 panE-2 panE-2 SPO1736 SPO1736 SPO1780 SPO1780 SPO1853 SPO1853 SPO1902 SPO1902 SPO2209 SPO2209 iseJ iseJ SPO2576 SPO2576 SPO2708 SPO2708 SPO2954 SPO2954 SPO3080 SPO3080 SPO3191 SPO3191 folK folK SPO3299 SPO3299 gabD-2 gabD-2 SPO3368 SPO3368 SPO3388 SPO3388 SPO3411 SPO3411 SPO3545 SPO3545 gshA gshA folC folC SPO3841 SPO3841 SPO3896 SPO3896
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPO0971Oxidoreductase, GMC family; Identified by match to protein family HMM PF00732; match to protein family HMM PF05199. (534 aa)
betBBetaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. (484 aa)
SPO0097Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (483 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (279 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (285 aa)
SPO0153Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (195 aa)
SPO0190Oxidoreductase, GMC family; Identified by match to protein family HMM PF00732; match to protein family HMM PF05199. (537 aa)
aasadhAlpha-aminoadipic semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (504 aa)
gshBGlutathione synthetase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family. (310 aa)
SPO0576Transcriptional regulator, TetR family; Identified by similarity to GB:AAS05297.1. (209 aa)
ggtGamma-glutamyltranspeptidase; Identified by similarity to SP:P54422. (597 aa)
SPO0743Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (198 aa)
SPO0799Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (220 aa)
SPO0866Gamma-glutamyltranspeptidase, putative; Identified by match to protein family HMM PF01019. (596 aa)
panE-12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (331 aa)
betIHTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. (192 aa)
betI-2Transcriptional regulator, TetR family; Repressor involved in choline regulation of the bet genes. (193 aa)
betACholine dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (552 aa)
doeCAspartate-semialdehyde dehydrogenase; Identified by similarity to SP:P25526; match to protein family HMM PF00171; match to protein family HMM TIGR01780. (491 aa)
folPDihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (264 aa)
SPO1484Hypothetical protein; Identified by similarity to GB:AAO56021.1. (164 aa)
panE-22-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (311 aa)
SPO1736Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (194 aa)
SPO1780Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (205 aa)
SPO1853Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (213 aa)
SPO1902Transcription regulator, TetR family; Identified by match to protein family HMM PF00440. (191 aa)
SPO2209Glutamate--cysteine ligase family protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (384 aa)
iseJIsethionate dehydrogenase; Identified by match to protein family HMM PF00732; match to protein family HMM PF05199; PMID: 19933343. (535 aa)
SPO2576Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (205 aa)
SPO2708Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (493 aa)
SPO2954Identified by match to protein family HMM PF01812; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (185 aa)
SPO3080Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (193 aa)
SPO3191Identified by match to protein family HMM PF00171. (483 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. (188 aa)
SPO3299Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (194 aa)
gabD-2Succinate-semialdehyde dehydrogenase; Identified by similarity to SP:P25526; match to protein family HMM PF00171; match to protein family HMM TIGR01780; Belongs to the aldehyde dehydrogenase family. (503 aa)
SPO3368Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (777 aa)
SPO3388Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (207 aa)
SPO3411Gamma-glutamyltranspeptidase, putative; Identified by match to protein family HMM PF01019. (525 aa)
SPO3545Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (185 aa)
gshAGlutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (456 aa)
folCfolC bifunctional protein; Identified by match to protein family HMM PF01225; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family. (424 aa)
SPO3841Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (205 aa)
SPO3896Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (203 aa)
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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