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| | purB | Adenylosuccinate lyase; Identified by similarity to SP:P12047; match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (434 aa) |
| | SPO2386 | Hypothetical protein; Identified by similarity to GB:AAM35187.1. (109 aa) |
| | coxF | Carbon monoxide dehydrogenase F protein; Identified by similarity to GB:CAB76248.1; match to protein family HMM PF02625. (260 aa) |
| | coxL-2 | Carbon monoxide dehydrogenase, large subunit; Identified by similarity to SP:P19919; match to protein family HMM PF01315; match to protein family HMM PF02738. (809 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | SPO2466 | Glyoxalase family protein; Identified by similarity to GB:AAN68182.1; match to protein family HMM PF00903. (125 aa) |
| | SPO2469 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. (273 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa) |
| | SPO2505 | Deoxyguanosinetriphosphate triphosphohydrolase, putative; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR01353; Belongs to the dGTPase family. Type 2 subfamily. (385 aa) |
| | SPO2566 | Identified by match to protein family HMM PF00903. (261 aa) |
| | SPO2598 | Hypothetical protein; Identified by Glimmer2; putative. (319 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) |
| | SPO2640 | Identified by match to protein family HMM PF02625. (326 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (490 aa) |
| | coaX | Transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (259 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Identified by similarity to SP:P39062; match to protein family HMM PF00501. (510 aa) |
| | SPO2881 | Xanthine dehydrogenase family protein, large subunit; Identified by match to protein family HMM PF01315; match to protein family HMM PF02738. (731 aa) |
| | add | Adenosine deaminase; Identified by match to protein family HMM PF00962; match to protein family HMM TIGR01430. (333 aa) |
| | prpE | propionate--CoA ligase; Identified by similarity to SP:P77495; match to protein family HMM PF00501. (629 aa) |
| | SPO2956 | Guanine deaminase, putative; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (427 aa) |
| | SPO2957 | Hydroxydechloroatrazine ethylaminohydrolase, putative; Identified by similarity to SP:P95442. (444 aa) |
| | SPO3019 | Xanthine dehydrogenase family protein, large subunit; Identified by match to protein family HMM PF01315; match to protein family HMM PF02738. (763 aa) |
| | mtaP | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (290 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (179 aa) |
| | SPO3081 | Identified by match to protein family HMM PF00903. (141 aa) |
| | SPO3101 | folD bifunctional protein; Identified by similarity to SP:P54382; match to protein family HMM PF00763; match to protein family HMM PF02882. (296 aa) |
| | atpC | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (136 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (474 aa) |
| | atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (291 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (512 aa) |
| | atpH | ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (186 aa) |
| | SPO3203 | guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase, putative; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (710 aa) |
| | atpF | ATP synthase F0, B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (190 aa) |
| | atpF-2 | ATP synthase F0, B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (181 aa) |
| | atpE | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (74 aa) |
| | atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (256 aa) |
| | purH | Bifunctional purine biosynthesis protein PurH; Identified by similarity to SP:P26978; match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. (529 aa) |
| | pyk | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (481 aa) |
| | mclA | malyl-CoA lyase; Identified by similarity to GB:AAB58884.1; match to protein family HMM TIGR01588; Belongs to the HpcH/HpaI aldolase family. (320 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa) |
| | badA-1 | Benzoate-coenzyme A ligase; Identified by similarity to GB:AAA92151.1; match to protein family HMM PF00501. (509 aa) |
| | amn | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (487 aa) |
| | ade | Adenine deaminase; Identified by similarity to SP:P39761; match to protein family HMM PF01979; match to protein family HMM TIGR01178; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (603 aa) |
| | SPO3747 | Hypothetical protein; Identified by similarity to GB:AAQ59692.1. (142 aa) |
| | acoA | Acetoin dehydrogenase complex, E1 component, alpha subunit; Identified by similarity to PIR:I40790; match to protein family HMM PF00676. (326 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (505 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (314 aa) |
| | SPO0115 | maoC family protein/phosphate acetyl/butaryl transferase; Identified by match to protein family HMM PF01515; match to protein family HMM PF01575. (464 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa) |
| | fliI | H+-transporting two-sector ATPase, flagellum-specific; Identified by similarity to SP:P26465; match to protein family HMM PF00006; match to protein family HMM TIGR01026. (445 aa) |
| | SPO0313 | Identified by match to protein family HMM PF00903. (126 aa) |
| | sucB | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (502 aa) |
| | sucA | 2-oxoglutarate dehydrogenase, E1 component; Identified by match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239. (985 aa) |
| | citE | Citrate lyase, beta subunit; Identified by similarity to SP:P77770; Belongs to the HpcH/HpaI aldolase family. (285 aa) |
| | deoD | Purine nucleoside phosphorylase; Identified by similarity to SP:O34925; match to protein family HMM PF01048; match to protein family HMM TIGR00107. (236 aa) |
| | SPO0404 | Identified by match to protein family HMM PF00300. (192 aa) |
| | coaBC | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (398 aa) |
| | SPO0440 | Thioesterase family protein. (130 aa) |
| | SPO0462 | Antibiotic biosynthesis monooxygenase domain protein. (108 aa) |
| | adk-1 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (213 aa) |
| | SPO0552 | Phosphoglycerate mutase family protein. (194 aa) |
| | SPO0585 | Dehydrogenase/transketolase family protein. (740 aa) |
| | xdhC | Xanthine dehydrogenase accessory factor; Identified by similarity to GB:CAB41849.1. (322 aa) |
| | SPO0680 | Glyoxalase family protein. (181 aa) |
| | SPO0684 | Glyoxalase family protein. (119 aa) |
| | SPO0721 | Glyoxalase family protein. (121 aa) |
| | SPO0830 | Xanthine dehydrogenase family protein, small/large subunits; Identified by match to protein family HMM PF00111; match to protein family HMM PF01315; match to protein family HMM PF01799; match to protein family HMM PF02738. (915 aa) |
| | SPO0831 | Xanthine dehydrogenase family protein, medium subunit; Identified by match to protein family HMM PF00941. (275 aa) |
| | SPO0864 | Glucokinase, putative; Belongs to the bacterial glucokinase family. (307 aa) |
| | SPO0871 | Identified by match to protein family HMM PF00576; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (118 aa) |
| | SPO0872 | Polysaccharide deacetylase family protein. (471 aa) |
| | allA | Ureidoglycolate hydrolase; Identified by similarity to SP:P77731; match to protein family HMM PF04115. (162 aa) |
| | SPO0876 | Hypothetical protein; Identified by similarity to GB:BAB51632.1; match to protein family HMM PF06038. (275 aa) |
| | SPO0880 | Hypothetical protein; Identified by similarity to PIR:T36459. (263 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (357 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (162 aa) |
| | SPO0917 | Identified by match to protein family HMM PF00903. (125 aa) |
| | SPO1016 | Hypothetical protein; Identified by Glimmer2; putative. (326 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02842; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM TIGR00877; Belongs to the GARS family. (420 aa) |
| | coxL-1 | Carbon monoxide dehydrogenase, large subunit; Identified by similarity to SP:P19913; match to protein family HMM PF01315; match to protein family HMM PF02738. (788 aa) |
| | folD1 | folD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (296 aa) |
| | folD | folD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (292 aa) |
| | SPO1565 | Citrate lyase, putative; Identified by similarity to SP:O53078; Belongs to the HpcH/HpaI aldolase family. (325 aa) |
| | SPO1603 | Identified by match to protein family HMM PF02615; Belongs to the LDH2/MDH2 oxidoreductase family. (350 aa) |
| | adk-2 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (227 aa) |
| | acs | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (719 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Identified by similarity to SP:P12046; match to protein family HMM PF01259; match to protein family HMM TIGR00081; Belongs to the SAICAR synthetase family. (251 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (76 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (222 aa) |
| | fda | Fructose-bisphosphate aldolase, class I; Identified by similarity to SP:Q07159; match to protein family HMM PF00274. (293 aa) |
| | SPO1915 | Identified by match to protein family HMM PF00903. (127 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (213 aa) |
| | SPO1958 | acyl-CoA thioesterase II; Identified by similarity to SP:P23911; match to protein family HMM PF02551; match to protein family HMM TIGR00189. (289 aa) |
| | SPO1959 | acetoacetyl-CoA synthase; Identified by similarity to SP:Q9Z3R3; match to protein family HMM PF00501; match to protein family HMM TIGR01217. (653 aa) |
| | SPO1970 | Identified by match to protein family HMM PF00300. (218 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (482 aa) |
| | pgi | Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342. (539 aa) |
| | hpt | Hypoxanthine phosphoribosyltransferase; Identified by similarity to SP:P37171; match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (519 aa) |
| | gpt | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (171 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (198 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878. (348 aa) |
| | hutF | Formiminoglutamate deiminase; Identified by match to protein family HMM PF01979; match to protein family HMM TIGR02022. (453 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (165 aa) |
| | SPO2215 | Identified by match to protein family HMM PF00903. (193 aa) |
| | pgk | Phosphoglycerate kinase; Identified by similarity to SP:P50314; match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | pdhA | Pyruvate dehydrogenase complex, E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (330 aa) |
| | pdhB | Pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (459 aa) |
| | pdhC | Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (437 aa) |
