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SPO0007 SPO0007 deoD deoD adk-1 adk-1 SPO0572 SPO0572 xdhB xdhB xdhA xdhA SPO0688 SPO0688 SPO0751 SPO0751 SPO0871 SPO0871 allA allA SPO0876 SPO0876 purK purK purE purE sat sat SPO0901 SPO0901 algC algC SPO1071 SPO1071 SPO1117 SPO1117 cpdA cpdA purA purA purD purD SPO1461 SPO1461 ureA ureA ureB ureB ureC ureC adk-2 adk-2 cpdA-2 cpdA-2 SPO1859 SPO1859 purL purL purC purC purS purS purQ purQ trgB trgB gmk gmk guaB guaB hpt hpt guaA guaA nrdJ nrdJ gpt gpt purN purN purM purM purB purB SPO2386 SPO2386 ndk ndk SPO2469 SPO2469 iunH iunH SPO2505 SPO2505 SPO2556 SPO2556 purF purF surE surE SPO2904 SPO2904 add add deoB deoB SPO2956 SPO2956 SPO2977 SPO2977 SPO2978 SPO2978 SPO3045 SPO3045 apt apt prs prs SPO3194 SPO3194 SPO3203 SPO3203 purH purH SPO3450 SPO3450 SPO3455 SPO3455 SPO3542 SPO3542 pyk pyk SPO3650 SPO3650 amn amn ade ade
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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SPO0007Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (204 aa)
deoDPurine nucleoside phosphorylase; Identified by similarity to SP:O34925; match to protein family HMM PF01048; match to protein family HMM TIGR00107. (236 aa)
adk-1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (213 aa)
SPO0572Adenylate/guanylate cyclase. (571 aa)
xdhBXanthine dehydrogenase, B subunit; Identified by similarity to GB:CAA04470.2. (776 aa)
xdhAXanthine dehydrogenase, A subunit; Identified by similarity to GB:CAA04469.1. (461 aa)
SPO0688Adenylate/guanylate cyclase. (415 aa)
SPO0751Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. (390 aa)
SPO0871Identified by match to protein family HMM PF00576; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (118 aa)
allAUreidoglycolate hydrolase; Identified by similarity to SP:P77731; match to protein family HMM PF04115. (162 aa)
SPO0876Hypothetical protein; Identified by similarity to GB:BAB51632.1; match to protein family HMM PF06038. (275 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (357 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (162 aa)
satSulfate adenylyltransferase; Catalyzes the synthesis of activated sulfate. (569 aa)
SPO0901Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00111; match to protein family HMM PF00211. (565 aa)
algCPhosphomannomutase/phosphoglucomutase; Identified by similarity to SP:P26276; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880. (498 aa)
SPO1071Glutamine amidotransferase, class-I; Identified by match to protein family HMM PF00117. (244 aa)
SPO1117Phosphatase, Ppx/GppA family; Identified by match to protein family HMM PF02541. (514 aa)
cpdASer/Thr protein phosphatase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (258 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa)
purDPhosphoribosylamine--glycine ligase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02842; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM TIGR00877; Belongs to the GARS family. (420 aa)
SPO1461Hypothetical protein; Identified by similarity to GB:BAC48692.1. (267 aa)
ureAUrease, gamma subunit; Identified by match to protein family HMM PF00547; match to protein family HMM TIGR00193; Belongs to the urease gamma subunit family. (100 aa)
ureBUrease, beta subunit; Identified by similarity to GB:BAB21066.1; match to protein family HMM PF00699; match to protein family HMM TIGR00192; Belongs to the urease beta subunit family. (101 aa)
ureCUrease, alpha subunit; Identified by match to protein family HMM PF00449; match to protein family HMM PF01979; match to protein family HMM TIGR01792; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (569 aa)
adk-2Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (227 aa)
cpdA-2Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (275 aa)
SPO1859Phosphatase, Ppx/GppA family; Identified by match to protein family HMM PF02541. (370 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (719 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Identified by similarity to SP:P12046; match to protein family HMM PF01259; match to protein family HMM TIGR00081; Belongs to the SAICAR synthetase family. (251 aa)
purSPhosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (76 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (222 aa)
trgBTellurite resistance protein; Identified by similarity to GB:AAB95442.1; match to protein family HMM PF00293; match to protein family HMM TIGR00052. (371 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (213 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (482 aa)
hptHypoxanthine phosphoribosyltransferase; Identified by similarity to SP:P37171; match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (519 aa)
nrdJRibonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1214 aa)
gptXanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (171 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (198 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878. (348 aa)
purBAdenylosuccinate lyase; Identified by similarity to SP:P12047; match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (434 aa)
SPO2386Hypothetical protein; Identified by similarity to GB:AAM35187.1. (109 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
SPO2469Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. (273 aa)
iunHInosine-uridine preferring nucleoside hydrolase; Identified by match to protein family HMM PF01156. (313 aa)
SPO2505Deoxyguanosinetriphosphate triphosphohydrolase, putative; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR01353; Belongs to the dGTPase family. Type 2 subfamily. (385 aa)
SPO2556N-carbamyl-L-amino acid amidohydrolase, putative; Identified by similarity to SP:P37113; match to protein family HMM PF01546; match to protein family HMM TIGR01879. (409 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (490 aa)
surEAcid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (260 aa)
SPO2904Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (524 aa)
addAdenosine deaminase; Identified by match to protein family HMM PF00962; match to protein family HMM TIGR01430. (333 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (403 aa)
SPO2956Guanine deaminase, putative; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (427 aa)
SPO2977Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. (329 aa)
SPO2978Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. (319 aa)
SPO3045Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. (267 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (179 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (339 aa)
SPO3194Ribonucleoside-diphosphate reductase, putative; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (760 aa)
SPO3203guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase, putative; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (710 aa)
purHBifunctional purine biosynthesis protein PurH; Identified by similarity to SP:P26978; match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. (529 aa)
SPO3450Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. (458 aa)
SPO3455Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF04248. (525 aa)
SPO35422`,3`-cyclic-nucleotide 2`-phosphodiesterase, putative; Identified by similarity to SP:P08331; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (623 aa)
pykPyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (481 aa)
SPO3650Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. (590 aa)
amnAMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (487 aa)
adeAdenine deaminase; Identified by similarity to SP:P39761; match to protein family HMM PF01979; match to protein family HMM TIGR01178; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (603 aa)
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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