(27 nodes) One carbon pool by folate network (Rhizopus delemar)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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protein homology

Your Input:
	RO3G_15085	Uncharacterized protein. (933 aa)
	RO3G_02981	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (598 aa)
	RO3G_03746	FSH1 domain-containing protein. (236 aa)
	RO3G_04074	Thymidylate synthase. (299 aa)
	RO3G_04834	UPF0176_N domain-containing protein. (107 aa)
	RO3G_05255	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (195 aa)
	RO3G_05777	TGT domain-containing protein. (283 aa)
	RO3G_05967	GCV_T domain-containing protein. (213 aa)
	RO3G_16533	Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (588 aa)
	RO3G_15096	Rhodanese domain-containing protein. (440 aa)
	RO3G_01777	Phosphoribosylglycinamide formyltransferase. (203 aa)
	RO3G_14479	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (562 aa)
	RO3G_17040	TGT domain-containing protein. (183 aa)
	RO3G_07399	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (500 aa)
	RO3G_07797	Uncharacterized protein. (177 aa)
	RO3G_07918	FSH1 domain-containing protein. (115 aa)
	RO3G_08072	Uncharacterized protein. (942 aa)
	RO3G_09046	Uncharacterized protein. (227 aa)
	RO3G_09625	Rhodanese domain-containing protein. (375 aa)
	RO3G_09792	5-formyltetrahydrofolate cyclo-ligase. (128 aa)
	RO3G_10655	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (467 aa)
	RO3G_10919	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1222 aa)
	RO3G_11101	Uncharacterized protein. (312 aa)
	RO3G_12349	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (529 aa)
	RO3G_13881	Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (373 aa)
	RO3G_13970	Formyl_trans_N domain-containing protein. (123 aa)
	RO3G_00886	Uncharacterized protein. (296 aa)

Your Current Organism:

Rhizopus delemar

NCBI taxonomy Id: 246409
Other names: R. delemar RA 99-880, Rhizopus delemar RA 99-880, Rhizopus delemar RA99-880

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RO3G_00886	RO3G_01777	I1BJ02	I1BLJ3	Uncharacterized protein.	Phosphoribosylglycinamide formyltransferase.	0.902
RO3G_00886	RO3G_02981	I1BJ02	I1BPZ7	Uncharacterized protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.803
RO3G_00886	RO3G_04074	I1BJ02	I1BT39	Uncharacterized protein.	Thymidylate synthase.	0.848
RO3G_00886	RO3G_05255	I1BJ02	I1BWH0	Uncharacterized protein.	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	0.894
RO3G_00886	RO3G_05777	I1BJ02	I1BXZ2	Uncharacterized protein.	TGT domain-containing protein.	0.538
RO3G_00886	RO3G_05967	I1BJ02	I1BYI2	Uncharacterized protein.	GCV_T domain-containing protein.	0.977
RO3G_00886	RO3G_07399	I1BJ02	I1C2L4	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.941
RO3G_00886	RO3G_07918	I1BJ02	I1C433	Uncharacterized protein.	FSH1 domain-containing protein.	0.798
RO3G_00886	RO3G_08072	I1BJ02	I1C4I7	Uncharacterized protein.	Uncharacterized protein.	0.858
RO3G_00886	RO3G_09792	I1BJ02	I1C9F2	Uncharacterized protein.	5-formyltetrahydrofolate cyclo-ligase.	0.852
RO3G_00886	RO3G_10655	I1BJ02	I1CBW5	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.941
RO3G_00886	RO3G_10919	I1BJ02	I1CCM8	Uncharacterized protein.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.816
RO3G_00886	RO3G_12349	I1BJ02	I1CGQ8	Uncharacterized protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.803
RO3G_00886	RO3G_13881	I1BJ02	I1CL40	Uncharacterized protein.	Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...]	0.656
RO3G_00886	RO3G_13970	I1BJ02	I1CLC9	Uncharacterized protein.	Formyl_trans_N domain-containing protein.	0.911
RO3G_00886	RO3G_14479	I1BJ02	I1CMT8	Uncharacterized protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.803
RO3G_00886	RO3G_15085	I1BJ02	I1CPJ4	Uncharacterized protein.	Uncharacterized protein.	0.858
RO3G_00886	RO3G_16533	I1BJ02	I1CTP2	Uncharacterized protein.	Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.879
RO3G_00886	RO3G_17040	I1BJ02	I1CUV3	Uncharacterized protein.	TGT domain-containing protein.	0.538
RO3G_01777	RO3G_00886	I1BLJ3	I1BJ02	Phosphoribosylglycinamide formyltransferase.	Uncharacterized protein.	0.902