(12 nodes) U2 snRNP, and Matrin/U1-C, C2H2-type zinc finger network (Coccidioides immitis RS)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CIMG_04653	U2 snRNP component HSH155, variant. (1228 aa)
	CIMG06451-2	Splicing factor 3a subunit 3. (501 aa)
	CIMG_12346	PHD finger-like domain-containing protein 5B. (110 aa)
	CIMG_00437	Pre-mRNA splicing factor. (580 aa)
	CIMG_10227	Pre-mRNA-splicing factor rse1. (1209 aa)
	CIMG_09202	U1 small nuclear ribonucleoprotein. (251 aa)
	CIMG_06339	Splicing factor 3b. (587 aa)
	CIMG_03896	Splicing factor subunit; Belongs to the SF3B5 family. (84 aa)
	CIMG_00993	Pre-mRNA branch site protein p14. (115 aa)
	CIMG_01605	Splicing factor 3a subunit 2. (239 aa)
	CIMG_02600	Splicing factor 3b subunit 4. (347 aa)
	PRP5	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily. (1197 aa)

Your Current Organism:

Coccidioides immitis RS

NCBI taxonomy Id: 246410
Other names: C. immitis RS

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CIMG06451-2	CIMG_00437	A0A0D8JWB0	A0A0E1RY37	Splicing factor 3a subunit 3.	Pre-mRNA splicing factor.	0.999
CIMG06451-2	CIMG_00993	A0A0D8JWB0	J3KI67	Splicing factor 3a subunit 3.	Pre-mRNA branch site protein p14.	0.959
CIMG06451-2	CIMG_01605	A0A0D8JWB0	J3KJK0	Splicing factor 3a subunit 3.	Splicing factor 3a subunit 2.	0.999
CIMG06451-2	CIMG_02600	A0A0D8JWB0	J3KLP6	Splicing factor 3a subunit 3.	Splicing factor 3b subunit 4.	0.997
CIMG06451-2	CIMG_03896	A0A0D8JWB0	J3KCC4	Splicing factor 3a subunit 3.	Splicing factor subunit; Belongs to the SF3B5 family.	0.994
CIMG06451-2	CIMG_04653	A0A0D8JWB0	A0A0D8JVP1	Splicing factor 3a subunit 3.	U2 snRNP component HSH155, variant.	0.992
CIMG06451-2	CIMG_06339	A0A0D8JWB0	J3K7Y6	Splicing factor 3a subunit 3.	Splicing factor 3b.	0.997
CIMG06451-2	CIMG_09202	A0A0D8JWB0	J3K1U6	Splicing factor 3a subunit 3.	U1 small nuclear ribonucleoprotein.	0.896
CIMG06451-2	CIMG_10227	A0A0D8JWB0	J3K125	Splicing factor 3a subunit 3.	Pre-mRNA-splicing factor rse1.	0.997
CIMG06451-2	CIMG_12346	A0A0D8JWB0	A0A0D8JWR7	Splicing factor 3a subunit 3.	PHD finger-like domain-containing protein 5B.	0.985
CIMG06451-2	PRP5	A0A0D8JWB0	Q1DHB2	Splicing factor 3a subunit 3.	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	0.997
CIMG_00437	CIMG06451-2	A0A0E1RY37	A0A0D8JWB0	Pre-mRNA splicing factor.	Splicing factor 3a subunit 3.	0.999
CIMG_00437	CIMG_00993	A0A0E1RY37	J3KI67	Pre-mRNA splicing factor.	Pre-mRNA branch site protein p14.	0.913
CIMG_00437	CIMG_01605	A0A0E1RY37	J3KJK0	Pre-mRNA splicing factor.	Splicing factor 3a subunit 2.	0.999
CIMG_00437	CIMG_02600	A0A0E1RY37	J3KLP6	Pre-mRNA splicing factor.	Splicing factor 3b subunit 4.	0.997
CIMG_00437	CIMG_03896	A0A0E1RY37	J3KCC4	Pre-mRNA splicing factor.	Splicing factor subunit; Belongs to the SF3B5 family.	0.980
CIMG_00437	CIMG_04653	A0A0E1RY37	A0A0D8JVP1	Pre-mRNA splicing factor.	U2 snRNP component HSH155, variant.	0.993
CIMG_00437	CIMG_06339	A0A0E1RY37	J3K7Y6	Pre-mRNA splicing factor.	Splicing factor 3b.	0.994
CIMG_00437	CIMG_09202	A0A0E1RY37	J3K1U6	Pre-mRNA splicing factor.	U1 small nuclear ribonucleoprotein.	0.859
CIMG_00437	CIMG_10227	A0A0E1RY37	J3K125	Pre-mRNA splicing factor.	Pre-mRNA-splicing factor rse1.	0.994