STRINGSTRING
DDIT3 DDIT3 L8Y725_TUPCH L8Y725_TUPCH CREB5 CREB5 ATF3 ATF3 CREB3L4 CREB3L4 RPS6KA5 RPS6KA5 ATF6B ATF6B WFS1 WFS1 ATF2 ATF2 ATF4 ATF4 L9KU93_TUPCH L9KU93_TUPCH XBP1 XBP1 DUSP12 DUSP12 ATF6 ATF6 PRKD2 PRKD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (172 aa)
L8Y725_TUPCHEukaryotic translation initiation factor 2-alpha kinase 3. (726 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (205 aa)
ATF3Cyclic AMP-dependent transcription factor ATF-3. (189 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4. (362 aa)
RPS6KA5Ribosomal protein S6 kinase alpha-5. (729 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta. (673 aa)
WFS1Wolframin. (1045 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2. (696 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (529 aa)
L9KU93_TUPCHSerine/threonine-protein kinase/endoribonuclease IRE2. (871 aa)
XBP1X-box-binding protein 1. (239 aa)
DUSP12Cyclic AMP-dependent transcription factor ATF-6 alpha. (692 aa)
ATF6Cyclic AMP-dependent transcription factor ATF-6 alpha. (73 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (876 aa)
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
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