STRINGSTRING
LHFPL2 LHFPL2 TMEM182 TMEM182 PMP22 PMP22 TMEM178B TMEM178B CACNG5 CACNG5 CACNG3 CACNG3 L9KPR1_TUPCH L9KPR1_TUPCH CLDN7 CLDN7 CLDN3 CLDN3 CLDN19 CLDN19 CLDN4 CLDN4 CLDN8 CLDN8 CACNG2 CACNG2 CLDN16 CLDN16 CLDN1 CLDN1 EMP3 EMP3 Claudin-22 Claudin-22 CLDN9 CLDN9 CACNG6 CACNG6 CACNG7 CACNG7 CACNG1 CACNG1 TMEM178A TMEM178A CLDN6 CLDN6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LHFPL2Lipoma HMGIC fusion partner-like 2 protein. (222 aa)
TMEM182Transmembrane protein 182. (145 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (159 aa)
TMEM178BTransmembrane protein 178. (224 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
CACNG3Voltage-dependent calcium channel gamma-3 subunit. (315 aa)
L9KPR1_TUPCHClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (337 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (238 aa)
CLDN16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
EMP3Epithelial membrane protein 3; Probably involved in cell proliferation and cell-cell interactions; Belongs to the PMP-22/EMP/MP20 family. (163 aa)
Claudin-22Claudin-22. (209 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
CACNG6Voltage-dependent calcium channel gamma-8 subunit. (602 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
TMEM178ATransmembrane protein 178. (264 aa)
CLDN6Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.