Your Input: | |
| | PGF | Ribosomal protein S6 kinase-like 1; Belongs to the PDGF/VEGF growth factor family. (1082 aa) |
| | FOS | Proto-oncogene c-Fos. (400 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | MAPKAPK3 | MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (373 aa) |
| | FLNB | Filamin-B. (2579 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (172 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (181 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (257 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | DUSP10 | Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (915 aa) |
| | FLNA | Filamin-A. (2589 aa) |
| | FGF10 | Fibroblast growth factor 10. (159 aa) |
| | RAC2 | Ras-related C3 botulinum toxin substrate 2. (192 aa) |
| | FLT1 | Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1057 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4. (349 aa) |
| | ELK1 | ETS domain-containing protein Elk-1. (385 aa) |
| | DUSP8 | Dual specificity protein phosphatase 8. (567 aa) |
| | HRAS | GTPase HRas. (187 aa) |
| | MKNK1 | MAP kinase-interacting serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (397 aa) |
| | NFKB2 | Nuclear factor NF-kappa-B p100 subunit. (893 aa) |
| | GNA12 | Guanine nucleotide-binding protein subunit alpha-12. (287 aa) |
| | NR4A1 | Nuclear receptor subfamily 4 group A member 1. (598 aa) |
| | IKBKG | NF-kappa-B essential modulator. (420 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf. (623 aa) |
| | NGFR | Tumor necrosis factor receptor superfamily member 16. (406 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (260 aa) |
| | DUSP16 | Dual specificity protein phosphatase 16. (663 aa) |
| | CACNA1B | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2195 aa) |
| | ANGPT4 | Angiopoietin-4. (497 aa) |
| | PLA2G4A | Phospholipase A2. (681 aa) |
| | RASGRP4 | RAS guanyl-releasing protein 4. (645 aa) |
| | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | ECSIT | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial. (425 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase. (152 aa) |
| | STK3 | Serine/threonine-protein kinase 3. (491 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (565 aa) |
| | RPS6KA1 | Ribosomal protein S6 kinase. (762 aa) |
| | CASP3 | Long-chain-fatty-acid--CoA ligase 1. (584 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase alpha-5. (729 aa) |
| | MAPK8IP2 | C-Jun-amino-terminal kinase-interacting protein 2. (872 aa) |
| | MAPK8IP1 | C-Jun-amino-terminal kinase-interacting protein 1. (596 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | CACNB4 | Voltage-dependent L-type calcium channel subunit beta-4. (471 aa) |
| | BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (216 aa) |
| | IL1RAP | Interleukin-1 receptor accessory protein. (260 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (351 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (266 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (507 aa) |
| | CACNG2 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (238 aa) |
| | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (327 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (688 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (310 aa) |
| | KITLG | Kit ligand. (295 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | HSPA1A | Heat shock 70 kDa protein 1; Belongs to the heat shock protein 70 family. (620 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa) |
| | EFNA4 | Ephrin-A4; Belongs to the ephrin family. (297 aa) |
| | DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) |
| | MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (457 aa) |
| | HSPA1L | Heat shock 70 kDa protein 1-like protein; Belongs to the heat shock protein 70 family. (641 aa) |
| | LAMTOR3 | Ragulator complex protein LAMTOR3. (124 aa) |
| | ARRB2 | Beta-arrestin-2. (409 aa) |
| | TAOK3 | Serine/threonine-protein kinase TAO3. (898 aa) |
| | EFNA1 | Ephrin-A1; Belongs to the ephrin family. (208 aa) |
| | SOS1 | Son of sevenless like protein 1. (1385 aa) |
| | CSF1R | Receptor protein-tyrosine kinase. (706 aa) |
| | TAB1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; Belongs to the TCP-1 chaperonin family. (703 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2. (696 aa) |
| | ATF4 | Cyclic AMP-dependent transcription factor ATF-4. (529 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1131 aa) |
| | PDGFD | Platelet-derived growth factor D. (329 aa) |
| | L9KPZ4_TUPCH | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (257 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (1020 aa) |
| | MAP3K11 | Mitogen-activated protein kinase kinase kinase. (860 aa) |
| | NGF | Beta-nerve growth factor; Belongs to the NGF-beta family. (268 aa) |
| | PRKACB | cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (119 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | TGFA | Protransforming growth factor alpha. (167 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase MLT. (440 aa) |
| | SRF | Inactive tyrosine-protein kinase 7. (1539 aa) |
| | HSPA8 | Heat shock cognate 71 kDa protein; Belongs to the heat shock protein 70 family. (650 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (155 aa) |
| | CACNG3 | Voltage-dependent calcium channel gamma-3 subunit. (315 aa) |
| | TAOK2 | Serine/threonine-protein kinase TAO2. (1270 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (528 aa) |
| | RAP1A | Ras-related protein Rap-1A. (184 aa) |
| | MAPKAPK5 | MAP kinase-activated protein kinase 5. (421 aa) |
| | STK4 | Serine/threonine-protein kinase 4. (536 aa) |
| | CACNG5 | Voltage-dependent calcium channel gamma-5 subunit. (275 aa) |
| | PRKCB | Non-specific serine/threonine protein kinase. (333 aa) |
| | RAC3 | Leucine-rich repeat-containing protein 45. (872 aa) |
| | PPP3R2 | Glutamate [NMDA] receptor subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1124 aa) |
| | CDC42 | Cell division control protein 42 like protein. (191 aa) |
| | PPM1A | Protein phosphatase 1A. (425 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | CACNG1 | Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa) |
| | CACNG7 | Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1375 aa) |
| | CACNG6 | Voltage-dependent calcium channel gamma-8 subunit. (602 aa) |
| | PTPRR | Receptor-type tyrosine-protein phosphatase R. (787 aa) |
| | GRB2 | Growth factor receptor-bound protein 2. (210 aa) |
| | RASGRF2 | Ras-specific guanine nucleotide-releasing factor 2. (134 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1003 aa) |
| | AREG | Amphiregulin. (251 aa) |
| | RRAS2 | Ras-related protein R-Ras2. (171 aa) |
| | HSPA6 | Heat shock 70 kDa protein 6; Belongs to the heat shock protein 70 family. (643 aa) |
| | HSPA2 | Heat shock-related 70 kDa protein 2. (921 aa) |
| | DAXX | Death domain-associated protein 6. (733 aa) |
| | CACNA1E | Voltage-dependent R-type calcium channel subunit alpha-1E. (136 aa) |
| | PLA2G4C | Cytosolic phospholipase A2 gamma. (636 aa) |
| | IGF1 | Insulin-like growth factor I. (182 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta. (768 aa) |
| | IGF2 | Insulin-like growth factor II. (261 aa) |
| | CRKL | Crk-like protein. (303 aa) |
| | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (497 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
