STRINGSTRING
GNG7 GNG7 RIN1 RIN1 GNB3 GNB3 PGF PGF FGF6 FGF6 FGF23 FGF23 SHC4 SHC4 FGF3 FGF3 FGF4 FGF4 RHOA RHOA NTF3 NTF3 PLA1A PLA1A PLA2G12B PLA2G12B FGF10 FGF10 RAC2 RAC2 RALB RALB FLT1 FLT1 RAB5B RAB5B ELK1 ELK1 ABL1 ABL1 HRAS HRAS ZAP70 ZAP70 IKBKG IKBKG GRIN2B GRIN2B GNGT2 GNGT2 NGFR NGFR VEGFD VEGFD PIK3R3 PIK3R3 L8YEE1_TUPCH L8YEE1_TUPCH ANGPT4 ANGPT4 CALMODULIN CALMODULIN RASAL3 RASAL3 PLA2G4A PLA2G4A RASGRP4 RASGRP4 CALML6 CALML6 GNG2 GNG2 ARF6 ARF6 RAF1 RAF1 FGF21 FGF21 CALML3 CALML3 CALML5 CALML5 CALM1 CALM1 FGF9 FGF9 GNG11 GNG11 BDNF BDNF GNGT1 GNGT1 GNG3 GNG3 PAK2 PAK2 RAB5C RAB5C RASA4 RASA4 GNB2 GNB2 PLA2G6 PLA2G6 TIAM1 TIAM1 KITLG KITLG EFNA4 EFNA4 CALML4 CALML4 SHC1 SHC1 PLCG2 PLCG2 PLA2G1B PLA2G1B KSR2 KSR2 PLD2 PLD2 EFNA1 EFNA1 SOS1 SOS1 CSF1R CSF1R PDGFRB PDGFRB PDGFD PDGFD L9KPZ4_TUPCH L9KPZ4_TUPCH PAK1 PAK1 NGF NGF RASAL1 RASAL1 PRKACB PRKACB FGF20 FGF20 NRAS NRAS TGFA TGFA PAK5 PAK5 FGF16 FGF16 VEGFA VEGFA MAPK3 MAPK3 PLA2G3 PLA2G3 HTR7 HTR7 PLCE1 PLCE1 RAP1A RAP1A STK4 STK4 PIK3R2 PIK3R2 GRIN2A GRIN2A PLA2G10 PLA2G10 PRKCB PRKCB GNG13 GNG13 BRAP BRAP FOXO4 FOXO4 PLA2G2A PLA2G2A RAC3 RAC3 PLA2G2F PLA2G2F PIK3CD PIK3CD CDC42 CDC42 PLA2G2D PLA2G2D FGF1 FGF1 GRB2 GRB2 RASGRF2 RASGRF2 PLA2G2C PLA2G2C PDGFRA PDGFRA KIT KIT RALA RALA RRAS2 RRAS2 SYNGAP1 SYNGAP1 RGL1 RGL1 PLA2G4C PLA2G4C IGF1 IGF1 IKBKB IKBKB IGF2 IGF2 RASAL2 RASAL2 INS INS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
RIN1Ras and Rab interactor 1. (803 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (342 aa)
PGFRibosomal protein S6 kinase-like 1; Belongs to the PDGF/VEGF growth factor family. (1082 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
SHC4Centrosomal protein of 152 kDa. (1478 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (181 aa)
RHOATransforming protein RhoA. (190 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (257 aa)
PLA1APhospholipase A1 member A. (431 aa)
PLA2G12BGroup XIIB secretory phospholipase A2-like protein. (190 aa)
FGF10Fibroblast growth factor 10. (159 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
RALBRas-related protein Ral-B. (206 aa)
FLT1Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1057 aa)
RAB5BRas-related protein Rab-5B. (215 aa)
ELK1ETS domain-containing protein Elk-1. (385 aa)
ABL1Tyrosine-protein kinase ABL1. (959 aa)
HRASGTPase HRas. (187 aa)
ZAP70Tyrosine-protein kinase. (577 aa)
IKBKGNF-kappa-B essential modulator. (420 aa)
GRIN2BGlutamate [NMDA] receptor subunit epsilon-2. (155 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (406 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (260 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (426 aa)
L8YEE1_TUPCHPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (807 aa)
ANGPT4Angiopoietin-4. (497 aa)
CALMODULINCalmodulin; Belongs to the calmodulin family. (150 aa)
RASAL3RAS protein activator like-3. (539 aa)
PLA2G4APhospholipase A2. (681 aa)
RASGRP4RAS guanyl-releasing protein 4. (645 aa)
CALML6Calmodulin-like protein 6. (203 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (152 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
CALML3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
CALML5Calmodulin-like protein 5. (148 aa)
CALM1Calmodulin; Belongs to the calmodulin family. (217 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (216 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PAK2Non-specific serine/threonine protein kinase. (507 aa)
RAB5CRas-related protein Rab-5C. (216 aa)
RASA4Ras GTPase-activating protein 4. (802 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
PLA2G685 kDa calcium-independent phospholipase A2. (806 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1. (1568 aa)
KITLGKit ligand. (295 aa)
EFNA4Ephrin-A4; Belongs to the ephrin family. (297 aa)
CALML4Calmodulin-like protein 4. (414 aa)
SHC1SHC-transforming protein 1. (785 aa)
PLCG21-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2. (131 aa)
PLA2G1BPhospholipase A(2). (147 aa)
KSR2Kinase suppressor of Ras 2. (196 aa)
PLD2Phospholipase. (882 aa)
EFNA1Ephrin-A1; Belongs to the ephrin family. (208 aa)
SOS1Son of sevenless like protein 1. (1385 aa)
CSF1RReceptor protein-tyrosine kinase. (706 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1131 aa)
PDGFDPlatelet-derived growth factor D. (329 aa)
L9KPZ4_TUPCHFibroblast growth factor; Belongs to the heparin-binding growth factors family. (257 aa)
PAK1Non-specific serine/threonine protein kinase. (1020 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (268 aa)
RASAL1RasGAP-activating-like protein 1. (797 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (119 aa)
NRASGTPase NRas. (189 aa)
TGFAProtransforming growth factor alpha. (167 aa)
PAK5Non-specific serine/threonine protein kinase. (713 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (155 aa)
MAPK3Mitogen-activated protein kinase. (528 aa)
PLA2G3Group 3 secretory phospholipase A2. (509 aa)
HTR75-hydroxytryptamine receptor 7. (398 aa)
PLCE1Phosphoinositide phospholipase C. (1707 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
STK4Serine/threonine-protein kinase 4. (536 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (793 aa)
GRIN2AGlutamate [NMDA] receptor subunit epsilon-1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1119 aa)
PLA2G10Phospholipase A(2). (181 aa)
PRKCBNon-specific serine/threonine protein kinase. (333 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (81 aa)
BRAPBRCA1-associated protein. (438 aa)
FOXO4Forkhead box protein O4. (529 aa)
PLA2G2APhospholipase A(2). (144 aa)
RAC3Leucine-rich repeat-containing protein 45. (872 aa)
PLA2G2FPhospholipase A(2). (241 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1074 aa)
CDC42Cell division control protein 42 like protein. (191 aa)
PLA2G2DPhospholipase A(2). (145 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
GRB2Growth factor receptor-bound protein 2. (210 aa)
RASGRF2Ras-specific guanine nucleotide-releasing factor 2. (134 aa)
PLA2G2CPhospholipase A(2). (282 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1003 aa)
RALARas-related protein Ral-A. (206 aa)
RRAS2Ras-related protein R-Ras2. (171 aa)
SYNGAP1Ras GTPase-activating protein SynGAP. (1062 aa)
RGL1Ral guanine nucleotide dissociation stimulator-like 1. (980 aa)
PLA2G4CCytosolic phospholipase A2 gamma. (636 aa)
IGF1Insulin-like growth factor I. (182 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (768 aa)
IGF2Insulin-like growth factor II. (261 aa)
RASAL2Ras GTPase-activating protein nGAP. (721 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
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