STRINGSTRING
GNG7 GNG7 PIK3CG PIK3CG GNB3 GNB3 XCR1 XCR1 CCR5 CCR5 CXCR4 CXCR4 PRKCD PRKCD CCR4 CCR4 SHC4 SHC4 ADCY6 ADCY6 RHOA RHOA CCR1 CCR1 CCL25 CCL25 CCR3 CCR3 RAC2 RAC2 CCR2 CCR2 CXCL14 CXCL14 HRAS HRAS IKBKG IKBKG GRK7 GRK7 GNGT2 GNGT2 CX3CR1 CX3CR1 CCR8 CCR8 PIK3R3 PIK3R3 L8YEE1_TUPCH L8YEE1_TUPCH GNG2 GNG2 RAF1 RAF1 GRK6 GRK6 PLCB2 PLCB2 CXCR2 CXCR2 GNG11 GNG11 FOXO3 FOXO3 GNGT1 GNGT1 ADCY8 ADCY8 GNG3 GNG3 CCR7 CCR7 STAT3 STAT3 CCL24 CCL24 CCL26 CCL26 GNB2 GNB2 TIAM1 TIAM1 FGR FGR NCF1 NCF1 ADCY5 ADCY5 CCL1 CCL1 CCL14 CCL14 L9KGB6_TUPCH L9KGB6_TUPCH CCL4 CCL4 CCL5 CCL5 CCL7 CCL7 CCL3 CCL3 PTK2B PTK2B SHC1 SHC1 PLCG2 PLCG2 CXCR5 CXCR5 CCL16 CCL16 ARRB2 ARRB2 CXCL16 CXCL16 PTK2 PTK2 ROCK1 ROCK1 CXCL13 CXCL13 SOS1 SOS1 PAK1 PAK1 PRKACB PRKACB NRAS NRAS CX3CL1 CX3CL1 MAPK3 MAPK3 PLCB3 PLCB3 CXCL12 CXCL12 RAP1A RAP1A GNAI3 GNAI3 ADCY3 ADCY3 XCL1 XCL1 PIK3R2 PIK3R2 PRKCB PRKCB GNG13 GNG13 RAC3 RAC3 GNAQ GNAQ PIK3CD PIK3CD CDC42 CDC42 CCR6 CCR6 ADCY4 ADCY4 GRB2 GRB2 ADCY2 ADCY2 L9L5M5_TUPCH L9L5M5_TUPCH L9L5M9_TUPCH L9L5M9_TUPCH CXCL11 CXCL11 PF4 PF4 CXCL9 CXCL9 CCL21 CCL21 CXCL8 CXCL8 CXCL10 CXCL10 SRC SRC GSK3A GSK3A CCL20 CCL20 ELMO1 ELMO1 IKBKB IKBKB PPBP PPBP ROCK2 ROCK2 CRKL CRKL ADCY9 ADCY9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (342 aa)
XCR1Chemokine XC receptor 1; Belongs to the G-protein coupled receptor 1 family. (333 aa)
CCR5C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (350 aa)
CXCR4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (290 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
CCR4C-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (350 aa)
SHC4Centrosomal protein of 152 kDa. (1478 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
RHOATransforming protein RhoA. (190 aa)
CCR1C-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
CCL25Dual specificity mitogen-activated protein kinase kinase 7. (586 aa)
CCR3C-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (358 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
CCR2C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
CXCL14C-X-C motif chemokine 14. (141 aa)
HRASGTPase HRas. (187 aa)
IKBKGNF-kappa-B essential modulator. (420 aa)
GRK7G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (553 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
CX3CR1CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (356 aa)
CCR8C-C chemokine receptor type 8; Belongs to the G-protein coupled receptor 1 family. (354 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (426 aa)
L8YEE1_TUPCHPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (807 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (152 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (603 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1191 aa)
CXCR2C-X-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (711 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
FOXO3Forkhead box protein O3. (514 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ADCY8Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (942 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CCR7C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (702 aa)
STAT3Signal transducer and activator of transcription 3. (747 aa)
CCL24C-C motif chemokine 24. (119 aa)
CCL26C-C motif chemokine. (89 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1. (1568 aa)
FGRTyrosine-protein kinase. (526 aa)
NCF1Neutrophil cytosol factor 1. (395 aa)
ADCY5Adenylate cyclase type 5. (321 aa)
CCL1C-C motif chemokine 1. (96 aa)
CCL14C-C motif chemokine 14. (96 aa)
L9KGB6_TUPCHC-C motif chemokine. (121 aa)
CCL4C-C motif chemokine. (92 aa)
CCL5C-C motif chemokine. (251 aa)
CCL7C-C motif chemokine. (98 aa)
CCL3C-C motif chemokine. (93 aa)
PTK2BProtein-tyrosine kinase 2-beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
SHC1SHC-transforming protein 1. (785 aa)
PLCG21-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2. (131 aa)
CXCR5C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (685 aa)
CCL16C-C motif chemokine 16. (114 aa)
ARRB2Beta-arrestin-2. (409 aa)
CXCL16C-X-C motif chemokine 16. (237 aa)
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1052 aa)
ROCK1Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1305 aa)
CXCL13C-X-C motif chemokine 13. (92 aa)
SOS1Son of sevenless like protein 1. (1385 aa)
PAK1Non-specific serine/threonine protein kinase. (1020 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
NRASGTPase NRas. (189 aa)
CX3CL1C-C motif chemokine. (544 aa)
MAPK3Mitogen-activated protein kinase. (528 aa)
PLCB3Phosphoinositide phospholipase C. (1208 aa)
CXCL12Stromal cell-derived factor 1. (101 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
ADCY3Adenylate cyclase type 3. (300 aa)
XCL1Lymphotactin. (260 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (793 aa)
PRKCBNon-specific serine/threonine protein kinase. (333 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (81 aa)
RAC3Leucine-rich repeat-containing protein 45. (872 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (323 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1074 aa)
CDC42Cell division control protein 42 like protein. (191 aa)
CCR6C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (258 aa)
ADCY4Guanylate cyclase. (1472 aa)
GRB2Growth factor receptor-bound protein 2. (210 aa)
ADCY2Adenylate cyclase type 2. (116 aa)
L9L5M5_TUPCHUncharacterized protein. (87 aa)
L9L5M9_TUPCHC-X-C motif chemokine. (485 aa)
CXCL11C-X-C motif chemokine. (128 aa)
PF4C-X-C motif chemokine. (107 aa)
CXCL9C-X-C motif chemokine. (126 aa)
CCL21C-C motif chemokine. (249 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)
CXCL10C-X-C motif chemokine. (319 aa)
SRCTyrosine-protein kinase. (526 aa)
GSK3AGlycogen synthase kinase-3 alpha. (936 aa)
CCL20C-C motif chemokine. (97 aa)
ELMO1Engulfment and cell motility protein 1. (857 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (768 aa)
PPBPC-X-C motif chemokine. (114 aa)
ROCK2Rho-associated protein kinase 2. (519 aa)
CRKLCrk-like protein. (303 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (815 aa)
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
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