STRINGSTRING
GLI1 GLI1 CCND2 CCND2 CCND1 CCND1 GLI2 GLI2 PTCH1 PTCH1 SPOP SPOP DHH DHH SUFU SUFU EVC2 EVC2 SPOPL SPOPL SMO SMO CSNK1E CSNK1E PTCH2 PTCH2 LRP2 LRP2 KIF7 KIF7 ARRB2 ARRB2 PRKACB PRKACB SHH SHH MGRN1 MGRN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLI1Zinc finger protein GLI1. (1104 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
GLI2Zinc finger protein GLI2. (1588 aa)
PTCH1Protein patched like protein 1. (1669 aa)
SPOPSpeckle-type POZ protein. (362 aa)
DHHProtein LMBR1L; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (1188 aa)
SUFUSuppressor of fused like protein. (102 aa)
EVC2Limbin. (1057 aa)
SPOPLSpeckle-type POZ protein-like protein. (180 aa)
SMOSmoothened like protein; Belongs to the G-protein coupled receptor Fz/Smo family. (1115 aa)
CSNK1ECasein kinase I isoform epsilon; Belongs to the protein kinase superfamily. (416 aa)
PTCH2Protein patched like protein 2. (1229 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4056 aa)
KIF7Kinesin-like protein KIF7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1320 aa)
ARRB2Beta-arrestin-2. (409 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
SHHSonic hedgehog protein. (207 aa)
MGRN1Non-histone chromosomal protein HMG-14. (125 aa)
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
Server load: low (14%) [HD]