STRINGSTRING
CDK4 CDK4 CCND1 CCND1 OCLN OCLN PRKAG1 PRKAG1 AMOT AMOT ACTR2 ACTR2 RHOA RHOA MARVELD2 MARVELD2 TUBA4A TUBA4A CRB3 CRB3 L8Y7C0_TUPCH L8Y7C0_TUPCH HSPA4 HSPA4 CGN CGN PCNA PCNA CLDN6 CLDN6 MYL6 MYL6 PARD6A PARD6A CLDN11 CLDN11 MSN MSN F11R F11R CLDN9 CLDN9 ACTN4 ACTN4 GATA4 GATA4 CLDN24 CLDN24 L9J9C8_TUPCH L9J9C8_TUPCH PRKCE PRKCE MYH14 MYH14 RAB13 RAB13 CD1D CD1D CD1C CD1C L9JBF0_TUPCH L9JBF0_TUPCH ACTN1 ACTN1 CLDN23 CLDN23 MPP5 MPP5 TUBAL3 TUBAL3 ITGB1 ITGB1 TUBA8 TUBA8 JAM2 JAM2 PPP2R1A PPP2R1A CD1E CD1E CLDN18 CLDN18 BVES BVES CLDN1 CLDN1 CLDN10 CLDN10 CLDN16 CLDN16 ERBB2 ERBB2 EZR EZR CLDN15 CLDN15 TIAM1 TIAM1 CLDN8 CLDN8 ARHGEF2 ARHGEF2 CLDN17 CLDN17 CLDN4 CLDN4 CLDN19 CLDN19 CLDN3 CLDN3 SCRIB SCRIB CLDN7 CLDN7 ROCK1 ROCK1 PRKAB1 PRKAB1 PPP2R2A PPP2R2A RDX RDX ACTR3 ACTR3 SYNPO SYNPO MARVELD3 MARVELD3 ACTR3B ACTR3B PRKACB PRKACB CLDN25 CLDN25 PATJ PATJ RAP1A RAP1A PPP2R2D PPP2R2D MYH11 MYH11 L9KY38_TUPCH L9KY38_TUPCH PRKAA2 PRKAA2 CLDN14 CLDN14 NF2 NF2 SLC9A3R1 SLC9A3R1 CDC42 CDC42 MAP3K5 MAP3K5 L9L2U8_TUPCH L9L2U8_TUPCH ACTG1 ACTG1 EPB41L4B EPB41L4B DLG2 DLG2 MYL9 MYL9 SRC SRC SYMPK SYMPK PARD6B PARD6B CGNL1 CGNL1 ROCK2 ROCK2 VASP VASP L9LBZ0_TUPCH L9LBZ0_TUPCH NEDD4L NEDD4L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDK4Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2. (1129 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
OCLNOccludin. (304 aa)
PRKAG1Histone-lysine N-methyltransferase MLL2. (3975 aa)
AMOTAngiomotin. (632 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (351 aa)
RHOATransforming protein RhoA. (190 aa)
MARVELD2MARVEL domain-containing protein 2. (541 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (447 aa)
CRB3Crumbs protein like protein 3. (73 aa)
L8Y7C0_TUPCHTubulin alpha-1C chain; Belongs to the tubulin family. (379 aa)
HSPA4Heat shock 70 kDa protein 4. (440 aa)
CGNCingulin. (1197 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
CLDN6Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
MYL6Myosin light chain 6B. (420 aa)
PARD6APartitioning defective 6 like protein alpha. (346 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
MSNMoesin. (573 aa)
F11RJunctional adhesion molecule A. (315 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
ACTN4Alpha-actinin-4. (866 aa)
GATA4Transcription factor GATA-4. (253 aa)
CLDN24Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (212 aa)
L9J9C8_TUPCHRas-related protein Rap-2c. (155 aa)
PRKCEProtein kinase C epsilon type. (145 aa)
MYH14Myosin-14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1997 aa)
RAB13Nuclear pore membrane glycoprotein 210-like protein. (2031 aa)
CD1DAntigen-presenting glycoprotein CD1d. (465 aa)
CD1CT-cell surface glycoprotein CD1c. (326 aa)
L9JBF0_TUPCHTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (440 aa)
ACTN1Alpha-actinin-1. (891 aa)
CLDN23Claudin-23. (185 aa)
MPP5MAGUK p55 subfamily member 5; Belongs to the MAGUK family. (649 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (446 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (741 aa)
TUBA8Tubulin alpha-8 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (1396 aa)
JAM2Junctional adhesion molecule B. (261 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (605 aa)
CD1ET-cell surface glycoprotein CD1e, membrane-associated. (1159 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
BVESBlood vessel epicardial substance. (368 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CLDN10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
CLDN16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
ERBB2Receptor protein-tyrosine kinase. (688 aa)
EZREzrin. (638 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (308 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1. (1568 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
ARHGEF2Uncharacterized protein. (198 aa)
CLDN17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (339 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
SCRIBProtein scribble like protein. (1566 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
ROCK1Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1305 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1. (231 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
RDXRadixin. (661 aa)
ACTR3Actin-related protein 3. (222 aa)
SYNPOSynaptopodin. (1220 aa)
MARVELD3MARVEL domain-containing protein 3. (213 aa)
ACTR3BActin-related protein 3B; Belongs to the actin family. (407 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
CLDN25Putative claudin-25. (228 aa)
PATJInaD-like protein. (1226 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform. (324 aa)
MYH11Myosin-11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2037 aa)
L9KY38_TUPCHMyosin regulatory light polypeptide 9. (309 aa)
PRKAA2Non-specific serine/threonine protein kinase. (391 aa)
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (239 aa)
NF2Merlin. (596 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (354 aa)
CDC42Cell division control protein 42 like protein. (191 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1375 aa)
L9L2U8_TUPCHMyosin regulatory light chain 12B. (172 aa)
ACTG1Actin, cytoplasmic 2. (430 aa)
EPB41L4BDOMON domain-containing protein. (382 aa)
DLG2Disks large like protein 2. (217 aa)
MYL9Myosin regulatory light polypeptide 9. (301 aa)
SRCTyrosine-protein kinase. (526 aa)
SYMPKSymplekin. (1229 aa)
PARD6BPartitioning defective 6 like protein beta. (366 aa)
CGNL1Cingulin-like protein 1. (1222 aa)
ROCK2Rho-associated protein kinase 2. (519 aa)
VASPVasodilator-stimulated phosphoprotein. (524 aa)
L9LBZ0_TUPCHTubulin alpha-3 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (290 aa)
NEDD4LE3 ubiquitin-protein ligase NEDD4-like protein. (201 aa)
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
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