64 items (Tupaia chinensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	GNB3	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (342 aa)
	HRAS	GTPase HRas. (187 aa)
	ARAF	Serine/threonine-protein kinase A-Raf. (623 aa)
	GNGT2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
	HTR2C	5-hydroxytryptamine receptor 2C. (284 aa)
	CACNA1B	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2195 aa)
	PLA2G4A	Phospholipase A2. (681 aa)
	DDC	Aromatic-L-amino-acid decarboxylase. (500 aa)
	PTGS2	Prostaglandin G/H synthase 2. (591 aa)
	HTR3C	5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (478 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	RAF1	RAF proto-oncogene serine/threonine-protein kinase. (152 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1191 aa)
	CASP3	Long-chain-fatty-acid--CoA ligase 1. (584 aa)
	APP	Amyloid beta A4 protein. (725 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	L9JJM4_TUPCH	5-hydroxytryptamine receptor 1A. (422 aa)
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	SLC18A1	Chromaffin granule amine transporter. (610 aa)
	GNB2	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
	HTR1F	5-hydroxytryptamine receptor 1F. (347 aa)
	L9KEZ8_TUPCH	Cytochrome P450 2J2; Belongs to the cytochrome P450 family. (502 aa)
	L9KFE0_TUPCH	Cytochrome P450 2J2; Belongs to the cytochrome P450 family. (502 aa)
	L9KFL7_TUPCH	Cytochrome P450 2J2; Belongs to the cytochrome P450 family. (394 aa)
	ADCY5	Adenylate cyclase type 5. (321 aa)
	L9KJV4_TUPCH	Cytochrome P450 2J2; Belongs to the cytochrome P450 family. (500 aa)
	ALOX15B	Arachidonate 15-lipoxygenase B. (702 aa)
	L9KLK0_TUPCH	Arachidonate 12-lipoxygenase, epidermal-type. (678 aa)
	ALOX12	Arachidonate 12-lipoxygenase, 12S-type. (661 aa)
	ALOX12B	Arachidonate 12-lipoxygenase, 12R-type. (652 aa)
	ALOX15	Proline-, glutamic acid-and leucine-rich protein 1. (1249 aa)
	HTR3A	5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (487 aa)
	PTGS1	Prostaglandin G/H synthase 1. (602 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	NRAS	GTPase NRas. (189 aa)
	MAOB	Amine oxidase. (520 aa)
	L9KSU9_TUPCH	Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (372 aa)
	GNAO1	Guanine nucleotide-binding protein G(O) subunit alpha. (111 aa)
	HTR4	5-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (337 aa)
	MAPK3	Mitogen-activated protein kinase. (528 aa)
	HTR7	5-hydroxytryptamine receptor 7. (398 aa)
	PLCB3	Phosphoinositide phospholipase C. (1208 aa)
	GNAI3	Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
	MAOA	Amine oxidase. (874 aa)
	PRKCB	Non-specific serine/threonine protein kinase. (333 aa)
	GNG13	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (81 aa)
	HTR1D	5-hydroxytryptamine receptor 1D. (377 aa)
	GNAQ	Guanine nucleotide-binding protein G(Q) subunit alpha. (323 aa)
	HTR5A	5-hydroxytryptamine receptor 5A. (405 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2646 aa)
	L9L593_TUPCH	5-hydroxytryptamine receptor 1E. (365 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (73 aa)
	HTR1B	5-hydroxytryptamine receptor 1B. (390 aa)
	TPH1	Tryptophan 5-hydroxylase 1. (1133 aa)
	PLA2G4C	Cytosolic phospholipase A2 gamma. (636 aa)
	GABRB1	Gamma-aminobutyric acid receptor subunit beta-1. (209 aa)
	HTR2A	5-hydroxytryptamine receptor 2A. (471 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2231 aa)
	KCNJ9	G protein-activated inward rectifier potassium channel 3. (395 aa)
	KCNN2	Small conductance calcium-activated potassium channel protein 2. (123 aa)
	KCNJ5	G protein-activated inward rectifier potassium channel 4. (463 aa)
	KCNJ6	G protein-activated inward rectifier potassium channel 2. (407 aa)

Your Current Organism:

Tupaia chinensis

NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	GNAI3	L9KG56	L9KVY5	Adenylate cyclase type 5.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.931
ADCY5	GNAO1	L9KG56	L9KTZ8	Adenylate cyclase type 5.	Guanine nucleotide-binding protein G(O) subunit alpha.	0.931
ADCY5	GNB2	L9KG56	L9K1E6	Adenylate cyclase type 5.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.	0.934
ADCY5	GNB3	L9KG56	L8Y0K2	Adenylate cyclase type 5.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.	0.932
ADCY5	GNG11	L9KG56	L9JFK2	Adenylate cyclase type 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.931
ADCY5	GNG13	L9KG56	L9KZ50	Adenylate cyclase type 5.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.942
ADCY5	GNG2	L9KG56	L9J8X7	Adenylate cyclase type 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.942
ADCY5	GNG3	L9KG56	L9JNG9	Adenylate cyclase type 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.936
ADCY5	GNG7	L9KG56	L8XZD1	Adenylate cyclase type 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.941
ADCY5	GNGT1	L9KG56	L9JJ08	Adenylate cyclase type 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.931
ADCY5	GNGT2	L9KG56	L8YBJ9	Adenylate cyclase type 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.941
ADCY5	PRKACB	L9KG56	L9KRH7	Adenylate cyclase type 5.	cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily.	0.926
ADCY5	PRKCB	L9KG56	L9KYN1	Adenylate cyclase type 5.	Non-specific serine/threonine protein kinase.	0.906
ALOX12	ALOX12B	L9KLL6	L9KM76	Arachidonate 12-lipoxygenase, 12S-type.	Arachidonate 12-lipoxygenase, 12R-type.	0.935
ALOX12	ALOX15	L9KLL6	L9KMD2	Arachidonate 12-lipoxygenase, 12S-type.	Proline-, glutamic acid-and leucine-rich protein 1.	0.909
ALOX12	ALOX15B	L9KLL6	L9KLF4	Arachidonate 12-lipoxygenase, 12S-type.	Arachidonate 15-lipoxygenase B.	0.933
ALOX12	L9KEZ8_TUPCH	L9KLL6	L9KEZ8	Arachidonate 12-lipoxygenase, 12S-type.	Cytochrome P450 2J2; Belongs to the cytochrome P450 family.	0.903
ALOX12	L9KFE0_TUPCH	L9KLL6	L9KFE0	Arachidonate 12-lipoxygenase, 12S-type.	Cytochrome P450 2J2; Belongs to the cytochrome P450 family.	0.903
ALOX12	L9KFL7_TUPCH	L9KLL6	L9KFL7	Arachidonate 12-lipoxygenase, 12S-type.	Cytochrome P450 2J2; Belongs to the cytochrome P450 family.	0.903
ALOX12	L9KJV4_TUPCH	L9KLL6	L9KJV4	Arachidonate 12-lipoxygenase, 12S-type.	Cytochrome P450 2J2; Belongs to the cytochrome P450 family.	0.903