61 items (Tupaia chinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (314 aa)
	GNB3	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (342 aa)
	FOS	Proto-oncogene c-Fos. (400 aa)
	CLOCK	Circadian locomoter output cycles protein kaput. (178 aa)
	CREB5	Cyclic AMP-responsive element-binding protein 5. (205 aa)
	GRIN2B	Glutamate [NMDA] receptor subunit epsilon-2. (155 aa)
	GNGT2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
	PPP2R3B	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (820 aa)
	GRIA2	Glutamate receptor 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (1375 aa)
	DRD5	D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (476 aa)
	CACNA1B	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2195 aa)
	CALMODULIN	Calmodulin; Belongs to the calmodulin family. (150 aa)
	DDC	Aromatic-L-amino-acid decarboxylase. (500 aa)
	DRD3	D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	CALML6	Calmodulin-like protein 6. (203 aa)
	PPP1CC	Serine/threonine-protein phosphatase. (237 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	CREB3L4	Cyclic AMP-responsive element-binding protein 3-like protein 4. (362 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1191 aa)
	CALML3	Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
	DRD1	D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (649 aa)
	CALML5	Calmodulin-like protein 5. (148 aa)
	CALM1	Calmodulin; Belongs to the calmodulin family. (217 aa)
	PPP2R1A	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (605 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	SLC18A1	Chromaffin granule amine transporter. (610 aa)
	GNB2	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
	ADCY5	Adenylate cyclase type 5. (321 aa)
	ATF6B	Cyclic AMP-dependent transcription factor ATF-6 beta. (673 aa)
	CALML4	Calmodulin-like protein 4. (414 aa)
	ARRB2	Beta-arrestin-2. (409 aa)
	PPP2R2A	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2. (696 aa)
	ATF4	Cyclic AMP-dependent transcription factor ATF-4. (529 aa)
	COMT	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (266 aa)
	PPP2R5B	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (498 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	GRIA4	Glutamate receptor 4. (126 aa)
	MAOB	Amine oxidase. (520 aa)
	DRD2	D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (328 aa)
	GNAO1	Guanine nucleotide-binding protein G(O) subunit alpha. (111 aa)
	PLCB3	Phosphoinositide phospholipase C. (1208 aa)
	GNAI3	Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
	PPP2R2D	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform. (324 aa)
	MAOA	Amine oxidase. (874 aa)
	GRIN2A	Glutamate [NMDA] receptor subunit epsilon-1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1119 aa)
	PPP2R5D	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (696 aa)
	PRKCB	Non-specific serine/threonine protein kinase. (333 aa)
	GNG13	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (81 aa)
	GNAQ	Guanine nucleotide-binding protein G(Q) subunit alpha. (323 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2646 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (73 aa)
	GSK3A	Glycogen synthase kinase-3 alpha. (936 aa)
	L9L9R7_TUPCH	Transmembrane O-methyltransferase. (258 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2231 aa)
	KCNJ9	G protein-activated inward rectifier potassium channel 3. (395 aa)
	KCNJ5	G protein-activated inward rectifier potassium channel 4. (463 aa)
	KCNJ6	G protein-activated inward rectifier potassium channel 2. (407 aa)

Your Current Organism:

Tupaia chinensis

NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	CALM1	L9KG56	L9JEG0	Adenylate cyclase type 5.	Calmodulin; Belongs to the calmodulin family.	0.693
ADCY5	CALML3	L9KG56	L9JCI0	Adenylate cyclase type 5.	Calmodulin-like protein 3; Belongs to the calmodulin family.	0.693
ADCY5	CALML4	L9KG56	L9KIP6	Adenylate cyclase type 5.	Calmodulin-like protein 4.	0.714
ADCY5	CALML5	L9KG56	L9JCM5	Adenylate cyclase type 5.	Calmodulin-like protein 5.	0.693
ADCY5	CALML6	L9KG56	L8YG95	Adenylate cyclase type 5.	Calmodulin-like protein 6.	0.689
ADCY5	CALMODULIN	L9KG56	L8YEW8	Adenylate cyclase type 5.	Calmodulin; Belongs to the calmodulin family.	0.693
ADCY5	GNAI3	L9KG56	L9KVY5	Adenylate cyclase type 5.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.931
ADCY5	GNAO1	L9KG56	L9KTZ8	Adenylate cyclase type 5.	Guanine nucleotide-binding protein G(O) subunit alpha.	0.931
ADCY5	GNB2	L9KG56	L9K1E6	Adenylate cyclase type 5.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.	0.934
ADCY5	GNB3	L9KG56	L8Y0K2	Adenylate cyclase type 5.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.	0.932
ADCY5	GNG11	L9KG56	L9JFK2	Adenylate cyclase type 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.931
ADCY5	GNG13	L9KG56	L9KZ50	Adenylate cyclase type 5.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.942
ADCY5	GNG2	L9KG56	L9J8X7	Adenylate cyclase type 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.942
ADCY5	GNG3	L9KG56	L9JNG9	Adenylate cyclase type 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.936
ADCY5	GNG7	L9KG56	L8XZD1	Adenylate cyclase type 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.941
ADCY5	GNGT1	L9KG56	L9JJ08	Adenylate cyclase type 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.931
ADCY5	GNGT2	L9KG56	L8YBJ9	Adenylate cyclase type 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.941
ADCY5	PRKACB	L9KG56	L9KRH7	Adenylate cyclase type 5.	cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily.	0.926
ADCY5	PRKCB	L9KG56	L9KYN1	Adenylate cyclase type 5.	Non-specific serine/threonine protein kinase.	0.906
ARRB2	DRD1	L9KLK5	L9JCI8	Beta-arrestin-2.	D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	0.445