STRINGSTRING
GNG7 GNG7 GNB3 GNB3 FOS FOS GNA15 GNA15 SHC4 SHC4 ADCY6 ADCY6 NOS2 NOS2 HRAS HRAS CREB5 CREB5 GNGT2 GNGT2 COL1A1 COL1A1 VEGFD VEGFD PIK3R3 PIK3R3 L8YEE1_TUPCH L8YEE1_TUPCH GNG2 GNG2 RAF1 RAF1 CREB3L4 CREB3L4 TGFBR2 TGFBR2 PLCB2 PLCB2 COL4A1 COL4A1 COL1A2 COL1A2 GNG11 GNG11 GNGT1 GNGT1 ADCY8 ADCY8 GNG3 GNG3 MAP2K4 MAP2K4 RXFP3 RXFP3 GNB2 GNB2 RXFP4 RXFP4 ADCY5 ADCY5 ATF6B ATF6B SHC1 SHC1 ARRB2 ARRB2 SOS1 SOS1 ATF2 ATF2 ATF4 ATF4 NOS3 NOS3 L9KPS3_TUPCH L9KPS3_TUPCH PRKACB PRKACB NRAS NRAS VEGFA VEGFA GNAO1 GNAO1 MAPK3 MAPK3 PLCB3 PLCB3 COL3A1 COL3A1 GNAI3 GNAI3 ADCY3 ADCY3 INSL3 INSL3 PIK3R2 PIK3R2 GNG13 GNG13 PIK3CD PIK3CD ADCY4 ADCY4 GRB2 GRB2 ADCY2 ADCY2 COL4A5 COL4A5 SRC SRC COL4A4 COL4A4 EDN1 EDN1 COL4A3 COL4A3 ADCY9 ADCY9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (342 aa)
FOSProto-oncogene c-Fos. (400 aa)
GNA15Guanine nucleotide-binding protein subunit alpha-15. (331 aa)
SHC4Centrosomal protein of 152 kDa. (1478 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1109 aa)
HRASGTPase HRas. (187 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (205 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
COL1A1Collagen alpha-1(I) chain. (480 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (260 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (426 aa)
L8YEE1_TUPCHPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (807 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (152 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4. (362 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (565 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1191 aa)
COL4A1Collagen alpha-1(IV) chain. (1559 aa)
COL1A2Collagen alpha-2(I) chain. (1195 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ADCY8Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (942 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (327 aa)
RXFP3Relaxin-3 receptor 1. (451 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
RXFP4Relaxin-3 receptor 2. (321 aa)
ADCY5Adenylate cyclase type 5. (321 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta. (673 aa)
SHC1SHC-transforming protein 1. (785 aa)
ARRB2Beta-arrestin-2. (409 aa)
SOS1Son of sevenless like protein 1. (1385 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2. (696 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (529 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1213 aa)
L9KPS3_TUPCHInterstitial collagenase. (466 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
NRASGTPase NRas. (189 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (155 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (111 aa)
MAPK3Mitogen-activated protein kinase. (528 aa)
PLCB3Phosphoinositide phospholipase C. (1208 aa)
COL3A1Collagen alpha-1(III) chain. (219 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
ADCY3Adenylate cyclase type 3. (300 aa)
INSL3Insulin-like 3. (124 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (793 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (81 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1074 aa)
ADCY4Guanylate cyclase. (1472 aa)
GRB2Growth factor receptor-bound protein 2. (210 aa)
ADCY2Adenylate cyclase type 2. (116 aa)
COL4A5Collagen alpha-1(IV) chain. (701 aa)
SRCTyrosine-protein kinase. (526 aa)
COL4A4Collagen alpha-1(IV) chain. (1527 aa)
EDN1Endothelin-1. (200 aa)
COL4A3Mitochondrial fission factor. (409 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (815 aa)
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
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