STRINGSTRING
KEZ53424.1 KEZ53424.1 KEZ53549.1 KEZ53549.1 KEZ53616.1 KEZ53616.1 KEZ53797.1 KEZ53797.1 nagB nagB KEZ53799.1 KEZ53799.1 murQ murQ KEZ53801.1 KEZ53801.1 KEZ53809.1 KEZ53809.1 KEZ53820.1 KEZ53820.1 KEZ53948.1 KEZ53948.1 KEZ53949.1 KEZ53949.1 KEZ53950.1 KEZ53950.1 KEZ54349.1 KEZ54349.1 KEZ53313.1 KEZ53313.1 KEZ53386.1 KEZ53386.1 KEZ53170.1 KEZ53170.1 KEZ52863.1 KEZ52863.1 KEZ52888.1 KEZ52888.1 KEZ52997.1 KEZ52997.1 KEZ53086.1 KEZ53086.1 pgi pgi zwf zwf KEZ51606.1 KEZ51606.1 deoC deoC KEZ51952.1 KEZ51952.1 KEZ51968.1 KEZ51968.1 pfkA pfkA KEZ52015.1 KEZ52015.1 KEZ52018.1 KEZ52018.1 eno eno gpmI gpmI tpiA tpiA pgk pgk KEZ52074.1 KEZ52074.1 KEZ52188.1 KEZ52188.1 KEZ52189.1 KEZ52189.1 nanE nanE glmU glmU prs prs KEZ49572.1 KEZ49572.1 KEZ49573.1 KEZ49573.1 KEZ49578.1 KEZ49578.1 KEZ49579.1 KEZ49579.1 KEZ49580.1 KEZ49580.1 KEZ49581.1 KEZ49581.1 KEZ49582.1 KEZ49582.1 KEZ49583.1 KEZ49583.1 KEZ48999.1 KEZ48999.1 KEZ49000.1 KEZ49000.1 KEZ49001.1 KEZ49001.1 KEZ49002.1 KEZ49002.1 KEZ49052.1 KEZ49052.1 tal tal KEZ48266.1 KEZ48266.1 KEZ48267.1 KEZ48267.1 KEZ48300.1 KEZ48300.1 KEZ48301.1 KEZ48301.1 KEZ48302.1 KEZ48302.1 KEZ47824.1 KEZ47824.1 glmM glmM glmS glmS KEZ47560.1 KEZ47560.1 KEZ47561.1 KEZ47561.1 KEZ47562.1 KEZ47562.1 pdxT pdxT pdxS pdxS rbsK rbsK KEZ47296.1 KEZ47296.1 KEZ47363.1 KEZ47363.1 serC serC KEZ47459.1 KEZ47459.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KEZ53424.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
KEZ53549.1Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
KEZ53616.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
KEZ53797.1N-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (251 aa)
KEZ53799.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
murQN-acetylmuramic acid-6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (302 aa)
KEZ53801.1PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
KEZ53809.1PTS sugar transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
KEZ53820.1PTS sugar transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
KEZ53948.1PtsGHI operon antiterminator; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
KEZ53949.1PTS system glucose-specific transporter subunit IICBA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (699 aa)
KEZ53950.1Phosphocarrier protein HPr; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)
KEZ54349.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa)
KEZ53313.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa)
KEZ53386.1LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
KEZ53170.1Catabolite control protein A; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
KEZ52863.1LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
KEZ52888.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
KEZ52997.1PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
KEZ53086.1D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (524 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (449 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (496 aa)
KEZ51606.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (223 aa)
KEZ51952.1Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (340 aa)
KEZ51968.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (586 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
KEZ52015.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
KEZ52018.1RpiR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
gpmIPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (511 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (394 aa)
KEZ52074.1Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
KEZ52188.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
KEZ52189.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
nanEN-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (244 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (451 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa)
KEZ49572.1Levansucrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 68 family. (488 aa)
KEZ49573.1Levanase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 32 family. (524 aa)
KEZ49578.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
KEZ49579.1PTS cellobiose transporter subunit IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (442 aa)
KEZ49580.1aryl-phospho-beta-D-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
KEZ49581.1Cytochrome C biogenesis protein CcmE; Derived by automated computational analysis using gene prediction method: Protein Homology. (102 aa)
KEZ49582.1PTS sorbose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
KEZ49583.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
KEZ48999.1Levansucrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
KEZ49000.1PTS system sucrose-specific transporter subuits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
KEZ49001.1Fructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (316 aa)
KEZ49002.1Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. (477 aa)
KEZ49052.1Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; induced by anaerobic conditions in Bacillus subtilis; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (214 aa)
KEZ48266.1Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (327 aa)
KEZ48267.1Glycoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 32 family. (487 aa)
KEZ48300.1PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (622 aa)
KEZ48301.1Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (303 aa)
KEZ48302.1DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
KEZ47824.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (448 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (600 aa)
KEZ47560.1Trehalose operon transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
KEZ47561.1Trehalose-6-phosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)
KEZ47562.1Trehalose permease IIC protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
pdxTGlutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (196 aa)
pdxSPyridoxal biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (294 aa)
rbsKHypothetical protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (298 aa)
KEZ47296.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
KEZ47363.1Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
serCMFS transporter; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (358 aa)
KEZ47459.1LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
Your Current Organism:
Bacillus indicus
NCBI taxonomy Id: 246786
Other names: B. indicus, Bacillus cibi, Bacillus cibi Yoon et al. 2005, Bacillus indicus Suresh et al. 2004 emend. Stropko et al. 2014, Bacillus sp. KU12, Bacillus sp. KU14, DSM 15820, DSM 16189 [[Bacillus cibi]], JCM 12168, KCTC 3880 [[Bacillus cibi]], LMG 22858, LMG:22858, MTCC 4374, strain JG-30 [[Bacillus cibi]], strain Sd/3
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