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mnmA mnmA nadE nadE NFA_42790 NFA_42790 gltX gltX argS argS valS valS nadD nadD cysD cysD cysH cysH NFA_14680 NFA_14680 cysD2 cysD2 gluQ gluQ NFA_28970 NFA_28970 NFA_29020 NFA_29020 mshC mshC NFA_29970 NFA_29970 NFA_30400 NFA_30400 phr phr cysD-2 cysD-2 NFA_34310 NFA_34310 NFA_35690 NFA_35690 NFA_38140 NFA_38140 tilS tilS ribF ribF panC panC coaD coaD kdpD kdpD ltsA ltsA ileS ileS NFA_19050 NFA_19050 argG argG tyrS tyrS thiI thiI hldE hldE trpS trpS guaA guaA leuS leuS NFA_54660 NFA_54660 metS metS NFA_46980 NFA_46980 NFA_46970 NFA_46970 cysS cysS NFA_42780 NFA_42780
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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mnmAPutative tRNA methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (372 aa)
nadEPutative NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (274 aa)
NFA_42790Putative electron transfer flavoprotein beta subunit. (261 aa)
gltXPutative glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (489 aa)
argSPutative arginyl-tRNA synthetase. (552 aa)
valSPutative valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (893 aa)
nadDHypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (222 aa)
cysDPutative sulfate adenylyltransferase subunit 2. (314 aa)
cysHPutative phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (239 aa)
NFA_14680Hypothetical protein. (231 aa)
cysD2Putative sulfate adenylyltransferase subunit 2. (310 aa)
gluQPutative aminoacyl-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (311 aa)
NFA_28970Hypothetical protein. (293 aa)
NFA_29020Hypothetical protein. (587 aa)
mshCPutative ATP-dependent L-cysteine:1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (412 aa)
NFA_29970Hypothetical protein. (296 aa)
NFA_30400Hypothetical protein. (345 aa)
phrPutative deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (436 aa)
cysD-2Putative ATP sulfurylase small subunit. (308 aa)
NFA_34310Hypothetical protein. (315 aa)
NFA_35690Hypothetical protein. (296 aa)
NFA_38140Hypothetical protein. (218 aa)
tilSHypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (318 aa)
ribFPutative riboflavin kinase; Belongs to the ribF family. (319 aa)
panCPutative pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (318 aa)
coaDPutative cytidylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa)
kdpDPutative two-component system sensor kinase. (828 aa)
ltsAPutative glutamine amidotransferase. (647 aa)
ileSPutative isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1042 aa)
NFA_19050Hypothetical protein. (150 aa)
argGPutative argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (400 aa)
tyrSPutative tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (429 aa)
thiIPutative thiamin biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (410 aa)
hldEHypothetical protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (506 aa)
trpSPutative tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (343 aa)
guaAPutative GMP synthase; Catalyzes the synthesis of GMP from XMP. (524 aa)
leuSPutative leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (950 aa)
NFA_54660Hypothetical protein. (159 aa)
metSPutative methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (518 aa)
NFA_46980Hypothetical protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (216 aa)
NFA_46970Hypothetical protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (135 aa)
cysSPutative cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (467 aa)
NFA_42780Putative electron transfer flavoprotein alpha subunit. (318 aa)
Your Current Organism:
Nocardia farcinica
NCBI taxonomy Id: 247156
Other names: N. farcinica IFM 10152, Nocardia farcinica IFM 10152, Nocardia farcinica str. IFM 10152, Nocardia farcinica strain IFM 10152
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