STRINGSTRING
gll2367 gll2367 proB proB gll0102 gll0102 lysA lysA gll0159 gll0159 gll0171 gll0171 nadA nadA glr0193 glr0193 gll0194 gll0194 gll0195 gll0195 glr0246 glr0246 glr0369 glr0369 glr0374 glr0374 glr0375 glr0375 glr0395 glr0395 bioF bioF glr0404 glr0404 tyrA tyrA hisH hisH ppc ppc leuA leuA metH metH gll0524 gll0524 gll0528 gll0528 argD argD gll0644 gll0644 glr0661 glr0661 glr0704 glr0704 hisA hisA serS serS glr0734 glr0734 gll0735 gll0735 fda fda trpF trpF gll0756 gll0756 panB panB gll0765 gll0765 hisB hisB glr0789 glr0789 cysK cysK gll0800 gll0800 dapF dapF cysS cysS gll0853 gll0853 glr0884 glr0884 gll0887 gll0887 glr0940 glr0940 glr0944 glr0944 gll0969 gll0969 gll0991 gll0991 glr1000 glr1000 glr1017 glr1017 dapA dapA fda-2 fda-2 gll1029 gll1029 aroA aroA tpi tpi argH argH glnA glnA glr1062 glr1062 glr1075 glr1075 gll1091 gll1091 gll1092 gll1092 gll1094 gll1094 gll1117 gll1117 gll1123 gll1123 thrB thrB gdhA gdhA ilvN ilvN gll1167 gll1167 gll1169 gll1169 dapB dapB hisIE hisIE gll1225 gll1225 accB accB gll1319 gll1319 hisC hisC hisD hisD purQ purQ glr1373 glr1373 glyQ glyQ glr1457 glr1457 thrC thrC glsF glsF pyrG pyrG glr1529 glr1529 glr1530 glr1530 glr1548 glr1548 glr1559 glr1559 gll1596 gll1596 accD accD glyS glyS gll1692 gll1692 gll1735 gll1735 ccmA ccmA glr1748 glr1748 gll1769 gll1769 cobQ cobQ gll1774 gll1774 gll1785 gll1785 gll1798 gll1798 glr1803 glr1803 gll1806 gll1806 glr1866 glr1866 gll1875 gll1875 gll1884 gll1884 aspS aspS gll1931 gll1931 gsl1937 gsl1937 gll1941 gll1941 gll1944 gll1944 gsl1945 gsl1945 gll1949 gll1949 gll1954 gll1954 gll1955 gll1955 gll1957 gll1957 gll1958 gll1958 gll1959 gll1959 gll1985 gll1985 gll1999 gll1999 accC accC glr2058 glr2058 thrC-2 thrC-2 purF purF gll2121 gll2121 serA serA gll2145 gll2145 gll2149 gll2149 gll2180 gll2180 gll2215 gll2215 gll2219 gll2219 gll2222 gll2222 gll2223 gll2223 gll2252 gll2252 gll2260 gll2260 leuA-2 leuA-2 gll2307 gll2307 acp acp pgk pgk gll2320 gll2320 glr2334 glr2334 gll2342 gll2342 alaS alaS gll2349 gll2349 thrC-3 thrC-3 gltX gltX hisS hisS gll2424 gll2424 aroQ aroQ glr2476 glr2476 glr2478 glr2478 gll2499 gll2499 gll2500 gll2500 aroB aroB cysE cysE gll2520 gll2520 gll2525 gll2525 glr2533 glr2533 glr2540 glr2540 gll2542 gll2542 gll2549 gll2549 gll2550 gll2550 trpC trpC hisS-2 hisS-2 gll2569 gll2569 ilvE ilvE gll2601 gll2601 trpA trpA glr2614 glr2614 guaA guaA desA desA glr2647 glr2647 ilvC ilvC gll2670 gll2670 glr2690 glr2690 glr2705 glr2705 aroK aroK putA putA trpB trpB glr2791 glr2791 trpD trpD gll2805 gll2805 glr2811 glr2811 gll2823 gll2823 gll2825 gll2825 gll2829 gll2829 gll2830 gll2830 gll2832 gll2832 glr2844 glr2844 glr2845 glr2845 glr2846 glr2846 glr2848 glr2848 glr2849 glr2849 gll2852 gll2852 gll2853 gll2853 gsl2854 gsl2854 glr2859 glr2859 accA accA gll2869 gll2869 pyrB pyrB thrS thrS valS valS pheT pheT argG argG glr2945 glr2945 trpS trpS metS metS glr3066 glr3066 glcD glcD glcE glcE icd icd glr3091 glr3091 gll3099 gll3099 argF argF pheS pheS glr3142 glr3142 gll3145 gll3145 gll3163 gll3163 ilvD ilvD gll3171 gll3171 gsl3203 gsl3203 gll3211 gll3211 aroE aroE ilvG ilvG gsl3282 gsl3282 glr3299 glr3299 gll3323 gll3323 gll3324 gll3324 gll3339 gll3339 lysS lysS hisG hisG aroC aroC gll3395 gll3395 gll3396 gll3396 leuC leuC glr3418 glr3418 gll3487 gll3487 gll3495 gll3495 glr3506 glr3506 bioD bioD glr3517 glr3517 gll3526 gll3526 glr3530 glr3530 glr3531 glr3531 gll3543 gll3543 glr3547 glr3547 leuB leuB gll3561 gll3561 glr3591 glr3591 gll3622 gll3622 glr3643 glr3643 ileS ileS glr3673 glr3673 glr3692 glr3692 cobB cobB gll3719 gll3719 desA-2 desA-2 glr3746 glr3746 gll3771 gll3771 glr3776 glr3776 glr3809 glr3809 glr3818 glr3818 gll3824 gll3824 glr3849 glr3849 gll3869 gll3869 proA proA argB argB gll3950 gll3950 glr3969 glr3969 gll3998 gll3998 glr4008 glr4008 argC argC glr4012 glr4012 gll4014 gll4014 argJ argJ gll4070 gll4070 leuS leuS glr4108 glr4108 glr4158 glr4158 glr4188 glr4188 glr4198 glr4198 gsl4224 gsl4224 gll4226 gll4226 glr4228 glr4228 gll4231 gll4231 glr4232 glr4232 glr4233 glr4233 glr4234 glr4234 gll4235 gll4235 argS argS thrA thrA hisF hisF bioB bioB gylA gylA tyrS tyrS
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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gll2367D-aminoacyl-tRNA deacylase; Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr). (263 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (369 aa)
gll01024-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (302 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (444 aa)
gll0159Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (647 aa)
gll0171ORF_ID:gll0171; similar to fatty acid desaturase. (390 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (319 aa)
glr0193ORF_ID:glr0193; carboxysome formation protein CcmA homolog. (342 aa)
gll01941-deoxy-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa)
gll0195Translation initiation factor IF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (348 aa)
glr0246Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (998 aa)
glr0369ORF_ID:glr0369; probable dehydrogenase. (344 aa)
glr0374N-acyl-L-amino acid amidohydrolase; ORF_ID:glr0374. (407 aa)
glr0375ORF_ID:glr0375; hypothetical protein. (582 aa)
glr0395ORF_ID:glr0395; hypothetical protein. (308 aa)
bioF7-keto-8-aminopelargonic acid synthetase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (388 aa)
glr0404ORF_ID:glr0404; hypothetical protein. (640 aa)
tyrAPrephenate dehydrogenase; ORF_ID:glr0406. (277 aa)
hisHAmidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (226 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (939 aa)
leuA2-isopropylmalate synthase; ORF_ID:gll0421; Belongs to the alpha-IPM synthase/homocitrate synthase family. (523 aa)
metH5-methyltetrahydrofolate--homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1196 aa)
gll0524Prephenate dehydratase; ORF_ID:gll0524. (277 aa)
gll0528ORF_ID:gll0528; hypothetical protein. (329 aa)
argDN-acetylornithine aminotransferase; ORF_ID:glr0547; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (404 aa)
gll0644ORF_ID:gll0644; unknown protein. (391 aa)
glr0661ORF_ID:glr0661; unknown protein. (384 aa)
glr0704Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (263 aa)
hisAPhosphorybosilformimino-5-amino-phosphorybosil- 4-imidazolecarboxamideisomerase; ORF_ID:glr0706. (255 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (429 aa)
glr0734Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (372 aa)
gll0735ORF_ID:gll0735; probable Zn-dependent alcohol dehydrogenase. (390 aa)
fdaFructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (356 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; ORF_ID:gll0754; Belongs to the TrpF family. (222 aa)
gll07562,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (536 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (262 aa)
gll0765Cysteine synthase; O-acetylserine (thiol) lyase B; ORF_ID:gll0765. (320 aa)
hisBImidazoleglycerol-phosphate dehydratase; ORF_ID:gll0769. (197 aa)
glr0789Methylenetetrahydrofolate reductase; ORF_ID:glr0789; hypothetical protein; Belongs to the methylenetetrahydrofolate reductase family. (297 aa)
cysKCysteine synthase; ORF_ID:glr0798; Belongs to the cysteine synthase/cystathionine beta- synthase family. (320 aa)
gll0800Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (338 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (283 aa)
cysScysteinyl-tRNA synthetase; ORF_ID:glr0851; Belongs to the class-I aminoacyl-tRNA synthetase family. (482 aa)
gll0853ORF_ID:gll0853; hypothetical protein. (140 aa)
glr0884ORF_ID:glr0884; hypothetical protein. (277 aa)
gll0887ORF_ID:gll0887; hypothetical protein. (316 aa)
glr0940Sorbitol dehydrogenase; ORF_ID:glr0940. (360 aa)
glr0944ORF_ID:glr0944; hypothetical protein. (178 aa)
gll0969UDP-glucose dehydrogenase; ORF_ID:gll0969. (456 aa)
gll0991ORF_ID:gll0991; unknown protein. (278 aa)
glr1000Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa)
glr1017Aspartate-semialdehyde dehydrogenase; ORF_ID:glr1017; Belongs to the aspartate-semialdehyde dehydrogenase family. (322 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (293 aa)
fda-2Fructose-bisphosphate aldolase class I; ORF_ID:gll1025. (358 aa)
gll1029Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (298 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (432 aa)
tpiTriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (240 aa)
argHL-argininosuccinate lyase; ORF_ID:gll1051. (468 aa)
glnAGlutamate--ammonia ligase; ORF_ID:glr1052. (472 aa)
glr1062UDP-glucose dehydrogenase; ORF_ID:glr1062. (463 aa)
glr1075ORF_ID:glr1075; probable acetyl-CoA synthetase. (923 aa)
gll10913-oxoacyl-[acyl-carrier-protein] synthase beta chain; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (423 aa)
gll1092Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; ORF_ID:gll1092; unknown protein. (384 aa)
gll1094ORF_ID:gll1094; probable 2-oxoisovalerate dehydrogenase, E1 component, alpha and beta subunit. (481 aa)
gll11176-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
gll1123ORF_ID:gll1123; unknown protein. (473 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (299 aa)
gdhAGlutamate dehydrogenase; ORF_ID:gll1133; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (458 aa)
ilvNAcetolactate synthase small subunit; ORF_ID:gll1136. (175 aa)
gll1167ORF_ID:gll1167; probable glucose dehydrogenase. (368 aa)
gll1169Glucokinase; ORF_ID:gll1169; Belongs to the bacterial glucokinase family. (327 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (269 aa)
hisIEphosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; ORF_ID:glr1211; histidine biosynthesis bifunctional; In the C-terminal section; belongs to the PRA-PH family. (218 aa)
gll1225Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (319 aa)
accBBiotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa)
gll1319ORF_ID:gll1319; unknown protein. (382 aa)
hisCHistidinol-phosphate aminotransferase; ORF_ID:gll1323; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (353 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (445 aa)
purQPhosphoribosylformyl glycinamidine synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (232 aa)
glr1373Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (417 aa)
glyQglycyl-tRNA synthetase alpha chain; ORF_ID:glr1446. (290 aa)
glr1457ORF_ID:glr1457; aspartate ammonia-lyase; aspartase. (469 aa)
thrCThreonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (362 aa)
glsFFerredoxin-dependent glutamate synthase; ORF_ID:glr1508. (1534 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (549 aa)
glr1529Pyruvate dehydrogenase E1 component alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (334 aa)
glr1530Pyruvate dehydrogenase E1 component beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
glr1548Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa)
glr1559ORF_ID:glr1559; hypothetical protein. (345 aa)
gll1596Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (232 aa)
accDacetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (304 aa)
glySglycyl-tRNA synthetase beta chain; ORF_ID:glr1646. (724 aa)
gll1692Glucose-6-phosphate isomerase; ORF_ID:gll1692. (548 aa)
gll1735ORF_ID:gll1735; hypothetical protein. (205 aa)
ccmACarboxysome formation protein; ORF_ID:glr1741. (354 aa)
glr1748ORF_ID:glr1748; hypothetical protein. (339 aa)
gll1769Carbamoyl phosphate synthetase large chain; ORF_ID:gll1769; Belongs to the CarB family. (1083 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (490 aa)
gll1774Aspartate kinase; ORF_ID:gll1774. (601 aa)
gll1785ORF_ID:gll1785; probable serine acetyltransferase. (171 aa)
gll1798UDP-glucose dehydrogenase; ORF_ID:gll1798. (458 aa)
glr1803ORF_ID:glr1803; unknown protein. (513 aa)
gll1806Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. (515 aa)
glr1866(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (142 aa)
gll1875Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (219 aa)
gll1884Methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (290 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (595 aa)
gll1931ORF_ID:gll1931; hypothetical protein. (553 aa)
gsl1937ORF_ID:gsl1937; hypothetical protein. (94 aa)
gll1941ORF_ID:gll1941; similar to polyketide synthase. (963 aa)
gll1944ORF_ID:gll1944; similar to polyketide synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (619 aa)
gsl1945ORF_ID:gsl1945; hypothetical protein. (95 aa)
gll1949ORF_ID:gll1949; probable oxidoreductase. (336 aa)
gll1954ORF_ID:gll1954; similar to polyketide synthase. (2049 aa)
gll1955ORF_ID:gll1955; similar to polyketide synthase. (103 aa)
gll1957ORF_ID:gll1957; probable glycolipid synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (1427 aa)
gll1958ORF_ID:gll1958; hypothetical protein. (816 aa)
gll1959ORF_ID:gll1959; probable glycolipid synthase. (1296 aa)
gll1985Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (813 aa)
gll1999Pyruvate kinase; ORF_ID:gll1999; probable pyruvate kinase; Belongs to the pyruvate kinase family. (501 aa)
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
glr2058ORF_ID:glr2058; hypothetical protein. (299 aa)
thrC-2Threonine synthase; ORF_ID:gll2062. (429 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (478 aa)
gll2121Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
serAD-3-phosphoglycerate dehydrogenase; ORF_ID:glr2139; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa)
gll2145Malonyl coenzyme A-acyl carrier protein transacylase; ORF_ID:gll2145. (295 aa)
gll2149Malic enzyme; ORF_ID:gll2149. (462 aa)
gll2180UDP-glucose dehydrogenase; ORF_ID:gll2180. (462 aa)
gll2215glutamine-fructose-6-P-aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
gll2219Histidine decarboxylase; ORF_ID:gll2219. (382 aa)
gll2222L-2,4-diaminobutyrate decarboxylase; ORF_ID:gll2222. (532 aa)
gll2223Diaminobutyrate--pyruvate transaminase; ORF_ID:gll2223; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (483 aa)
gll2252Deoxyxylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (392 aa)
gll2260Zinc-type alcohol dehydrogenase-like protein; ORF_ID:gll2260; probable oxidoreductase; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. (337 aa)
leuA-22-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (538 aa)
gll2307ORF_ID:gll2307; hypothetical protein. (307 aa)
acpAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (103 aa)
pgkPhosphoglycerate kinase; ORF_ID:glr2313; Belongs to the phosphoglycerate kinase family. (407 aa)
gll2320Small subunit of soluble hydrogenase; ORF_ID:gll2320. (385 aa)
glr2334ORF_ID:glr2334; hypothetical protein. (258 aa)
gll2342glutamyl-tRNA(Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (554 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (871 aa)
gll2349ORF_ID:gll2349; similar to alanyl-tRNA synthetase. (449 aa)
thrC-3Threonine synthase; ORF_ID:gll2362. (395 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (530 aa)
hisShistidyl-tRNA synthetase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (392 aa)
gll24245'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (299 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (160 aa)
glr2476Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (169 aa)
glr2478L-allo-threonine aldolase; ORF_ID:glr2478. (344 aa)
gll2499Glutamine synthetase III; ORF_ID:gll2499; Belongs to the glutamine synthetase family. (436 aa)
gll2500Proable homoserine O-acetyltransferase; ORF_ID:gll2500; Belongs to the AB hydrolase superfamily. MetX family. (341 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (361 aa)
cysESerine acetyltransferase; ORF_ID:glr2514. (244 aa)
gll25203-oxoacyl-[acyl-carrier-protein] synthase; ORF_ID:gll2520; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (367 aa)
gll2525prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (589 aa)
glr2533ORF_ID:glr2533; tagatose-bisphosphate aldolase GatY homolog. (296 aa)
glr2540ORF_ID:glr2540; probable hydrolase. (406 aa)
gll2542Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (325 aa)
gll25496-oxocamphor hydrolase; ORF_ID:gll2549. (254 aa)
gll25503-oxoacyl-(acyl-carrier-protein) reductase; ORF_ID:gll2550. (181 aa)
trpCIndole-3-glycerol phosphate synthase; ORF_ID:gll2556; Belongs to the TrpC family. (295 aa)
hisS-2histidyl-tRNA synthetase; ORF_ID:gll2557. (467 aa)
gll2569Dihydrolipoamide S-acetyltransferase; ORF_ID:gll2569. (419 aa)
ilvEBranched-chain amino acid aminotransferase; ORF_ID:gll2582. (291 aa)
gll2601ORF_ID:gll2601; probable aminotransferase. (412 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (276 aa)
glr2614N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (243 aa)
guaAGMP synthetase; Catalyzes the synthesis of GMP from XMP. (551 aa)
desADelta 12 acyl-lipid desaturase; ORF_ID:glr2623. (352 aa)
glr26472-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; ORF_ID:glr2647. (356 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa)
gll2670ORF_ID:gll2670; probable amino acid decarboxylase. (494 aa)
glr2690ORF_ID:glr2690; similar to phosphoenolpyruvate synthase. (940 aa)
glr2705Chorismate mutase AroH; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (123 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (177 aa)
putA1-pyrroline-5-carboxylate dehydrogenase; ORF_ID:glr2755; Belongs to the aldehyde dehydrogenase family. (996 aa)
trpBTryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (414 aa)
glr27914-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (233 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (342 aa)
gll2805Succinate-semialdehyde dehydrogenase; ORF_ID:gll2805. (462 aa)
glr2811ORF_ID:glr2811; hypothetical protein. (383 aa)
gll2823ORF_ID:gll2823; hypothetical protein. (333 aa)
gll2825Quinone oxidoreductase; ORF_ID:gll2825. (329 aa)
gll2829ORF_ID:gll2829; similar to polyketide synthase. (1199 aa)
gll2830ORF_ID:gll2830; similar to polyketide synthase. (108 aa)
gll2832ORF_ID:gll2832; hypothetical protein. (869 aa)
glr2844Pyruvate dehydrogenase E1 alpha-subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (331 aa)
glr2845L-aspartate-alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (118 aa)
glr2846Pyruvate dehydrogenase E1 beta-subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
glr2848ORF_ID:glr2848; probable glycolipid synthase. (1335 aa)
glr2849ORF_ID:glr2849; hypothetical protein. (804 aa)
gll2852ORF_ID:gll2852; probable beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (390 aa)
gll2853ORF_ID:gll2853; probable beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (466 aa)
gsl2854Acyl carrier protein; ORF_ID:gsl2854. (87 aa)
glr2859ORF_ID:glr2859; probable oxidoreductase. (333 aa)
accAacetyl-CoA carboxylase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (326 aa)
gll2869ORF_ID:gll2869; hypothetical protein. (299 aa)
pyrBAspartate carbamoyltransferase; ORF_ID:gll2875; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (329 aa)
thrSthreonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (627 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (897 aa)
pheTphenylalanyl-tRNA synthetase; ORF_ID:gll2926; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (785 aa)
argGArgininosuccinate synthase; ORF_ID:glr2933; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (398 aa)
glr2945Succinate dehydrogenase chain C; ORF_ID:glr2945. (298 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (336 aa)
metSmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (516 aa)
glr3066Histidine ammonia-lyase; ORF_ID:glr3066; Belongs to the PAL/histidase family. (514 aa)
glcDGlycolate oxidase subunit; ORF_ID:glr3069. (489 aa)
glcEGlycolate oxidase subunit; ORF_ID:glr3071. (435 aa)
icdIsocitrate dehydrogenase; ORF_ID:gll3088. (359 aa)
glr30914-hydroxyphenylpyruvate dioxygenase; ORF_ID:glr3091. (344 aa)
gll3099Dipeptide epimerase; ORF_ID:gll3099; similar to chloromuconate cycloisomerase. (356 aa)
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (313 aa)
pheSphenylalanyl-tRNA synthetase alpha chain; ORF_ID:glr3128; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (338 aa)
glr3142ORF_ID:glr3142; hypothetical protein. (161 aa)
gll3145ORF_ID:gll3145; hypothetical protein. (350 aa)
gll3163ORF_ID:gll3163; unknown protein. (307 aa)
ilvDDihydroxyacid dehydratase; ORF_ID:gll3168; Belongs to the IlvD/Edd family. (560 aa)
gll3171ORF_ID:gll3171; unknown protein. (445 aa)
gsl3203ORF_ID:gsl3203; unknown protein. (93 aa)
gll3211ORF_ID:gll3211; hypothetical protein. (256 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (285 aa)
ilvGAcetohydroxyacid synthetase large subunit; ORF_ID:glr3279. (596 aa)
gsl3282glutamyl-tRNA(Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (95 aa)
glr32994-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (417 aa)
gll3323Pyruvate kinase; ORF_ID:gll3323; Belongs to the pyruvate kinase family. (473 aa)
gll3324L-lactate dehydrogenase A chain; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (330 aa)
gll3339Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (252 aa)
lysSlysyl-tRNA synthetase; ORF_ID:gll3356; Belongs to the class-II aminoacyl-tRNA synthetase family. (497 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (214 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (395 aa)
gll3395ORF_ID:gll3395; similar to Xaa-Pro dipeptidase. (233 aa)
gll3396ORF_ID:gll3396; similar to Xaa-Pro dipeptidase. (254 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (473 aa)
glr34183-isopropylmalate dehydratase small subunit; ORF_ID:glr3418; Belongs to the LeuD family. (206 aa)
gll3487Lysine decarboxylase; ORF_ID:gll3487. (467 aa)
gll3495Pyruvate kinase; ORF_ID:gll3495; Belongs to the pyruvate kinase family. (605 aa)
glr35063-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
bioDDethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (229 aa)
glr3517ORF_ID:glr3517; hypothetical protein. (441 aa)
gll3526Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (289 aa)
glr3530Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (367 aa)
glr3531Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gll3543Carbamoyl phosphate synthase small subunit; ORF_ID:gll3543; Belongs to the CarA family. (384 aa)
glr35472-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (163 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (362 aa)
gll3561Lactoylglutathione lyase; ORF_ID:gll3561. (144 aa)
glr3591ORF_ID:glr3591; hypothetical protein. (223 aa)
gll36224-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (396 aa)
glr3643ORF_ID:glr3643; unknown protein. (386 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (983 aa)
glr3673ORF_ID:glr3673; hypothetical protein. (386 aa)
glr3692Beta-ketoacyl-acyl carrier protein synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (329 aa)
cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (452 aa)
gll3719UDP-glucose dehydrogenase; ORF_ID:gll3719. (462 aa)
desA-2Delta 12 acyl-lipid desaturase; ORF_ID:gll3735. (355 aa)
glr3746Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (379 aa)
gll3771ORF_ID:gll3771; unknown protein. (334 aa)
glr3776Phosphoglycerate dehydrogenase; ORF_ID:glr3776; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
glr3809ORF_ID:glr3809; hypothetical protein. (526 aa)
glr3818Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (381 aa)
gll3824ORF_ID:gll3824; probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase. (262 aa)
glr38494-aminobutyrate aminotransferase; ORF_ID:glr3849; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
gll3869Serine/threonine dehydratase; ORF_ID:gll3869. (331 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (303 aa)
gll3950L-cysteine/cystine lyase; ORF_ID:gll3950. (378 aa)
glr3969Alanine dehydrogenase; ORF_ID:glr3969; Belongs to the AlaDH/PNT family. (364 aa)
gll3998ORF_ID:gll3998; probable isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (409 aa)
glr4008Acyl-carrier protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (132 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (350 aa)
glr4012N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (306 aa)
gll40143-oxoacyl-[acyl-carrier-protein] synthase beta chain; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (415 aa)
argJArginine biosynthesis bifunctional protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (406 aa)
gll4070Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. (644 aa)
leuSleucyl-tRNA synthetase; ORF_ID:gll4081; Belongs to the class-I aminoacyl-tRNA synthetase family. (847 aa)
glr4108LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. Can also use m-DAP instead of LL-DAP as the amino- group donor. (392 aa)
glr4158ORF_ID:glr4158; hypothetical protein. (297 aa)
glr4188Enoyl-[acyl-carrier-protein] reductase; ORF_ID:glr4188. (258 aa)
glr4198ORF_ID:glr4198; similar to coronafacate ligase. (197 aa)
gsl4224ORF_ID:gsl4224; probable acyl carrier protein. (94 aa)
gll4226ORF_ID:gll4226; probable modular polyketide synthase. (3029 aa)
glr4228Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (125 aa)
gll4231ORF_ID:gll4231; unknown protein. (409 aa)
glr4232ORF_ID:glr4232; unknown protein. (378 aa)
glr4233ORF_ID:glr4233; unknown protein. (372 aa)
glr4234ORF_ID:glr4234; unknown protein. (385 aa)
gll4235ORF_ID:gll4235; unknown protein. (406 aa)
argSarginyl-tRNA synthetase; ORF_ID:glr4279. (601 aa)
thrAHomoserine dehydrogenase; ORF_ID:gll4295. (427 aa)
hisFImidazoleglycerol-phosphate synthase cyclase-subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (254 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (318 aa)
gylASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (426 aa)
tyrSTyrosyl tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (402 aa)
Your Current Organism:
Gloeobacter violaceus
NCBI taxonomy Id: 251221
Other names: G. violaceus PCC 7421, Gloeobacter violaceus ATCC 29082, Gloeobacter violaceus PCC 7421, Gloeobacter violaceus str. PCC 7421, Gloeobacter violaceus strain PCC 7421
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