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leuB leuB Chro_1125 Chro_1125 Chro_1898 Chro_1898 Chro_2103 Chro_2103 Chro_2169 Chro_2169 Chro_2326 Chro_2326 ilvD ilvD Chro_4502 Chro_4502 Chro_4594 Chro_4594 Chro_4779 Chro_4779 ilvC ilvC
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second shell of interactors
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leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (363 aa)
Chro_1125Thiamine pyrophosphate TPP-binding domain-containing protein; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001:IPR012000:IPR011766:IPR000399; KEGG: npu:Npun_R2059 thiamine pyrophosphate binding domain-containing protein; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; SPTR: Thiamine pyrophosphate enzyme TPP bi [...] (563 aa)
Chro_1898Acetolactate synthase, large subunit; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001:IPR012000:IPR011766; KEGG: ava:Ava_3533 acetolactate synthase; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; SPTR: Acetolactate synthase. (547 aa)
Chro_2103PFAM: Aconitase family (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit; homoaconitate hydratase family protein; COGs: COG0065 3-isopropylmalate dehydratase large subunit; InterPro IPR011826:IPR006251:IPR001030; KEGG: ter:Tery_2728 homoaconitate hydratase family protein; PFAM: aconitate hydratase domain-containing protein; SPTR: Homoaconitate hydratase family protein; TIGRFAM: homoaconitate hydratase family protein; 3-isopropylmalate dehydratase; Belongs to the aconitase/IPM isomerase family. (439 aa)
Chro_2169Thiamine pyrophosphate TPP-binding domain-containing protein; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: npu:Npun_R2059 thiamine pyrophosphate binding domain-containing protein; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; SPTR: Thiamine pyrophosphate protein TPP b [...] (569 aa)
Chro_2326PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit; COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR004789:IPR002912:IPR019455; KEGG: ava:Ava_2035 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit. (174 aa)
ilvDPFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR004404:IPR002114:IPR020558:IPR000581; KEGG: cyc:PCC7424_2821 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (561 aa)
Chro_4502PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; COGs: COG0066 3-isopropylmalate dehydratase small subunit; InterPro IPR000573:IPR011827; KEGG: ter:Tery_1041 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain-containing protein; SPTR: 3-isopropylmalate dehydratase, small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family. (181 aa)
Chro_4594PFAM: HMGL-like; TIGRFAM: homocitrate synthase NifV; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR002034:IPR013477; KEGG: npu:Npun_F0430 trans-homoaconitate synthase; PFAM: pyruvate carboxyltransferase; SPTR: Homocitrate synthase; TIGRFAM: homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (395 aa)
Chro_4779Acetolactate synthase, large subunit; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterProIPR012001:IPR012000:IPR011766:IPR000399:IPR 012846; KEGG: npu:Npun_R1735 acetolactate synthase 3 catalytic subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; SPTR: [...] (632 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa)
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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