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Chro_2087 Chro_2087 Chro_0076 Chro_0076 recO recO infA infA rpsQ rpsQ rplB rplB asnS asnS Chro_0289 Chro_0289 ruvA ruvA recG recG aspS aspS rsgA rsgA Chro_1809 Chro_1809 Chro_1810 Chro_1810 Chro_1966 Chro_1966 Chro_2231 Chro_2231 lysS lysS ligA ligA Chro_3164 Chro_3164 Chro_3370 Chro_3370 rimO rimO Chro_3902 Chro_3902 efp efp Chro_4066 Chro_4066 pnp pnp pheT pheT Chro_4375 Chro_4375 Chro_4738 Chro_4738 rpsL rpsL Chro_4886 Chro_4886 nusA nusA Chro_5209 Chro_5209 Chro_5450 Chro_5450
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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Chro_2087Exoribonuclease II; PFAM: RNB domain; COGs: COG0557 Exoribonuclease R; InterPro IPR001900; KEGG: naz:Aazo_5174 exoribonuclease II; PFAM: ribonuclease II; PRIAM: Exoribonuclease II; SPTR: Exoribonuclease II. (687 aa)
Chro_0076Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003439:IPR013611:IPR003593:IPR017871; KEGG: npu:Npun_F5477 ABC transporter related; PFAM: ABC transporter related; Transport-associated OB domain-containing protein; SMART: AAA ATPase; SPTR: ABC transporter related; Belongs to the ABC transporter superfamily. (367 aa)
recODNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (319 aa)
infABacterial translation initiation factor 1 (bIF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (74 aa)
rpsQSSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (95 aa)
rplBLSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (287 aa)
asnSPFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase; COGs: COG0017 Aspartyl/asparaginyl-tRNA synthetase; InterProIPR004365:IPR004364:IPR002312:IPR006195:IPR 004522; KEGG: npu:Npun_R0874 asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Asparaginyl-tRNA synthetase; TIGRFAM: asparaginyl-tRNA synthetase. (462 aa)
Chro_0289PFAM: TRAM domain; tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR002792:IPR000241:IPR010280:IPR001566; KEGG: npu:Npun_R0877 RNA methyltransferase; PFAM: deoxyribonuclease/rho motif-related TRAM; RNA methylase; SPTR: 23S rRNA methyltransferase/RumA; TIGRFAM: RNA methyltransferase, TrmA family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (471 aa)
ruvAHolliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (209 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (857 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (602 aa)
rsgARibosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (368 aa)
Chro_1809SSU ribosomal protein S1P; PFAM: S1 RNA binding domain; COGs: COG0539 Ribosomal protein S1; InterPro IPR003029:IPR000110; KEGG: npu:Npun_F0856 RNA-binding S1 domain-containing protein; PFAM: RNA binding S1 domain protein; SPTR: RNA binding S1 domain protein; manually curated. (300 aa)
Chro_1810Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter; TOBE domain; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003439:IPR017871:IPR003593:IPR013611; KEGG: amr:AM1_1478 sugar ABC transporter, ATP-binding protein; PFAM: ABC transporter related; Transport-associated OB domain-containing protein; SMART: AAA ATPase; SPTR: Sugar ABC transporter, ATP-binding protein. (367 aa)
Chro_1966Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter; TOBE domain; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR017871:IPR003439:IPR013611:IPR003593; KEGG: ava:Ava_2050 ABC transporter-like; PFAM: ABC transporter related; Transport-associated OB domain-containing protein; SMART: AAA ATPase; SPTR: ABC transporter-like. (441 aa)
Chro_2231Export-related chaperone CsaA; PFAM: Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; export-related chaperone CsaA; COGs: COG0073 EMAP domain; InterPro IPR002547:IPR008231; KEGG: pmr:PMI1031 protein secretion chaperone; PFAM: t-RNA-binding domain-containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: export-related chaperone CsaA. (118 aa)
lysSPFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR006195:IPR018149:IPR002313:IPR004365:IPR 004364; KEGG: npu:Npun_R5202 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (501 aa)
ligADNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (677 aa)
Chro_3164PFAM: Tex-like protein N-terminal domain; S1 RNA binding domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; COGs: COG2183 Transcriptional accessory protein; InterPro IPR018974:IPR003029:IPR006641; KEGG: npu:Npun_R5425 RNA-binding S1 domain-containing protein; PFAM: Tex-like protein-like; RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; SPTR: RNA binding S1 domain protein. (718 aa)
Chro_3370PFAM: Single-strand binding protein family; COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: cyn:Cyan7425_1502 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein. (160 aa)
rimOSSU ribosomal protein S12P methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (439 aa)
Chro_3902PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb); COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: ana:alr7579 single-strand DNA binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein. (129 aa)
efpTranslation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (186 aa)
Chro_4066PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb); COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: npu:Npun_F1842 single-stranded DNA-binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein. (122 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (716 aa)
pheTphenylalanyl-tRNA synthetase beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR002547:IPR005121:IPR004532:IPR005146:IPR 005147; KEGG: npu:Npun_F1087 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; PRIAM: Phenylalanine--tRNA ligase; SPTR: Phenyla [...] (822 aa)
Chro_4375Ribonuclease, Rne/Rng family; PFAM: Ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family; COGs: COG1530 Ribonuclease G and E; InterPro IPR003029:IPR019307:IPR004659; KEGG: ava:Ava_1281 ribonuclease E and G; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; RNA binding S1 domain protein; PRIAM: Ribonuclease E; SPTR: Ribonuclease E and G; TIGRFAM: ribonuclease, Rne/Rng family. (702 aa)
Chro_4738PFAM: ABC transporter; TOBE domain; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003439:IPR013611:IPR017871:IPR003593; KEGG: ara:Arad_9638 sugar ABC transporter; PFAM: ABC transporter related; Transport-associated OB domain-containing protein; SMART: AAA ATPase; SPTR: TOBE domain family. (381 aa)
rpsLSSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa)
Chro_4886PFAM: Ribonuclease B OB domain; RNB domain; S1 RNA binding domain; TIGRFAM: VacB and RNase II family 3'-5' exoribonucleases; COGs: COG0557 Exoribonuclease R; InterPro IPR003029:IPR013223:IPR001900:IPR011129; KEGG: npu:Npun_F6222 VacB/RNase II family 3'-5' exoribonuclease; PFAM: ribonuclease II; Ribonuclease B OB region domain; RNA binding S1 domain protein; SMART: Cold shock protein; SPTR: VacB and RNase II family 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (774 aa)
nusANusA antitermination factor; Participates in both transcription termination and antitermination. (444 aa)
Chro_5209Protein of unknown function DUF107; PFAM: NfeD-like; COGs: COG1585 Membrane protein implicated in regulation of membrane protease activity; InterPro IPR002810; KEGG: ava:Ava_0403 hypothetical protein; PFAM: protein of unknown function DUF107; SPTR: Putative uncharacterized protein. (144 aa)
Chro_5450SSU ribosomal protein S1P; PFAM: S1 RNA binding domain; COGs: COG0539 Ribosomal protein S1; InterPro IPR003029:IPR000110; KEGG: ava:Ava_1505 30S ribosomal protein S1; PFAM: RNA binding S1 domain protein; SPTR: 30S ribosomal protein S1. (356 aa)
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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