STRINGSTRING
SIS51565.1 SIS51565.1 SIS51763.1 SIS51763.1 SIS53338.1 SIS53338.1 SIS54306.1 SIS54306.1 SIS54330.1 SIS54330.1 SIS54356.1 SIS54356.1 SIS54381.1 SIS54381.1 SIS54406.1 SIS54406.1 SIS54426.1 SIS54426.1 SIS54558.1 SIS54558.1 SIS54579.1 SIS54579.1 SIS54655.1 SIS54655.1 acpP acpP SIS54695.1 SIS54695.1 SIS54716.1 SIS54716.1 SIS54741.1 SIS54741.1 SIS54761.1 SIS54761.1 SIS54783.1 SIS54783.1 SIS55396.1 SIS55396.1 accD accD accA accA SIS56606.1 SIS56606.1 SIS56630.1 SIS56630.1 SIS56655.1 SIS56655.1 SIS56678.1 SIS56678.1 SIS65668.1 SIS65668.1 SIS65685.1 SIS65685.1 SIS67672.1 SIS67672.1 SIS67689.1 SIS67689.1 SIS67704.1 SIS67704.1 SIS67717.1 SIS67717.1 SIS67729.1 SIS67729.1 SIS67749.1 SIS67749.1 SIS67764.1 SIS67764.1 SIS67777.1 SIS67777.1 SIS67796.1 SIS67796.1 SIS67811.1 SIS67811.1 SIS67887.1 SIS67887.1 SIS63102.1 SIS63102.1 SIS63125.1 SIS63125.1 SIS73013.1 SIS73013.1 SIS73162.1 SIS73162.1 SIS73890.1 SIS73890.1 SIS73907.1 SIS73907.1 SIS73923.1 SIS73923.1 SIS74372.1 SIS74372.1 SIS74389.1 SIS74389.1 SIS74402.1 SIS74402.1 SIS74415.1 SIS74415.1 SIS74429.1 SIS74429.1 SIS74472.1 SIS74472.1 SIS74499.1 SIS74499.1 SIS74508.1 SIS74508.1 SIS74522.1 SIS74522.1 SIS74535.1 SIS74535.1 SIS74549.1 SIS74549.1 SIS74562.1 SIS74562.1 SIS74580.1 SIS74580.1 SIS74594.1 SIS74594.1 SIS74610.1 SIS74610.1 SIS74678.1 SIS74678.1 SIS74695.1 SIS74695.1 SIS74709.1 SIS74709.1 SIS75126.1 SIS75126.1 fabZ fabZ SIS79517.1 SIS79517.1 SIS79531.1 SIS79531.1 SIS79544.1 SIS79544.1 SIS79574.1 SIS79574.1 SIS79587.1 SIS79587.1 SIS77874.1 SIS77874.1 SIS80214.1 SIS80214.1 SIS80235.1 SIS80235.1 SIS80473.1 SIS80473.1 SIS80501.1 SIS80501.1 SIS81350.1 SIS81350.1 SIS77778.1 SIS77778.1 SIS79142.1 SIS79142.1 fabH fabH SIS85336.1 SIS85336.1 SIS85353.1 SIS85353.1 SIS85372.1 SIS85372.1 SIS85383.1 SIS85383.1 SIS85399.1 SIS85399.1 SIS85415.1 SIS85415.1 SIS85431.1 SIS85431.1 SIS85464.1 SIS85464.1 SIS85479.1 SIS85479.1 SIS85489.1 SIS85489.1 SIS85504.1 SIS85504.1 SIS85556.1 SIS85556.1 SIS85574.1 SIS85574.1 SIS85589.1 SIS85589.1 SIS85605.1 SIS85605.1 SIS85619.1 SIS85619.1 SIS85635.1 SIS85635.1 SIS85652.1 SIS85652.1 SIS85668.1 SIS85668.1 SIS85700.1 SIS85700.1 SIS89644.1 SIS89644.1 SIS89661.1 SIS89661.1 SIS89674.1 SIS89674.1 SIS89685.1 SIS89685.1 SIS89704.1 SIS89704.1 SIS89716.1 SIS89716.1 SIS89729.1 SIS89729.1 SIS89744.1 SIS89744.1 SIS89795.1 SIS89795.1 SIS89806.1 SIS89806.1 SIS89836.1 SIS89836.1 SIS89854.1 SIS89854.1 SIS91172.1 SIS91172.1 SIS92500.1 SIS92500.1 SIS94434.1 SIS94434.1 SIS94452.1 SIS94452.1 SIS94469.1 SIS94469.1 SIS94485.1 SIS94485.1 SIS94503.1 SIS94503.1 SIS94519.1 SIS94519.1 SIS94535.1 SIS94535.1 SIS94552.1 SIS94552.1 SIS94589.1 SIS94589.1 SIS94606.1 SIS94606.1 SIS94796.1 SIS94796.1 SIS92690.1 SIS92690.1 SIS92703.1 SIS92703.1 SIS92718.1 SIS92718.1 SIS93033.1 SIS93033.1 SIS97562.1 SIS97562.1 SIS97581.1 SIS97581.1 SIS97597.1 SIS97597.1 SIS97611.1 SIS97611.1 SIS97628.1 SIS97628.1 SIS97641.1 SIS97641.1 SIS97656.1 SIS97656.1 SIS97670.1 SIS97670.1 SIS97686.1 SIS97686.1 SIT01082.1 SIT01082.1 plsX plsX SIT01124.1 SIT01124.1 SIT01143.1 SIT01143.1 acpP-2 acpP-2 SIT01182.1 SIT01182.1 SIS99204.1 SIS99204.1 SIS99834.1 SIS99834.1 acsA acsA SIT00071.1 SIT00071.1 SIT03958.1 SIT03958.1 SIT05217.1 SIT05217.1 SIT08228.1 SIT08228.1 SIT12040.1 SIT12040.1 SIT13731.1 SIT13731.1 SIT13743.1 SIT13743.1 SIT13757.1 SIT13757.1 SIT14491.1 SIT14491.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SIS51565.1Lysophospholipase, alpha-beta hydrolase superfamily. (311 aa)
SIS51763.1Tricorn interacting aminopeptidase F1. Serine peptidase. MEROPS family S33. (255 aa)
SIS53338.1Acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase. (646 aa)
SIS54306.13-oxoacyl-[acyl-carrier-protein] synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (419 aa)
SIS54330.1Enoyl-[acyl-carrier-protein] reductase [NADH]. (258 aa)
SIS54356.1acyl-CoA thioester hydrolase. (135 aa)
SIS54381.1NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family. (255 aa)
SIS54406.1Uncharacterized conserved protein YndB, AHSA1/START domain. (142 aa)
SIS54426.1Hypothetical protein. (108 aa)
SIS54558.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase. (343 aa)
SIS54579.1Acyl-CoA dehydrogenase. (385 aa)
SIS54655.1Enoyl-[acyl-carrier protein] reductase III. (259 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (84 aa)
SIS54695.1cyclohexanecarboxylate-CoA ligase/acyl-CoA synthetase. (552 aa)
SIS54716.1Acyl-CoA dehydrogenase. (408 aa)
SIS54741.1Alcohol dehydrogenase/alcohol dehydrogenase, propanol-preferring. (344 aa)
SIS54761.1Hypothetical protein. (195 aa)
SIS54783.1Hypothetical protein. (72 aa)
SIS55396.1Pimeloyl-ACP methyl ester carboxylesterase. (272 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (299 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa)
SIS56606.1Transcriptional regulator, DeoR family. (254 aa)
SIS56630.1Coat F domain-containing protein. (228 aa)
SIS56655.1Hypothetical protein. (112 aa)
SIS56678.1Hypothetical protein. (403 aa)
SIS65668.1Putative cyclase. (318 aa)
SIS65685.1Long-chain acyl-CoA synthetase. (563 aa)
SIS67672.1Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
SIS67689.1Acetyl-CoA carboxylase, carboxyltransferase component. (515 aa)
SIS67704.1hydroxymethylglutaryl-CoA lyase. (301 aa)
SIS67717.1acetyl-CoA carboxylase biotin carboxyl carrier protein. (71 aa)
SIS67729.1acetyl-CoA carboxylase, biotin carboxylase subunit. (446 aa)
SIS67749.1Acyl-CoA dehydrogenase. (377 aa)
SIS67764.1acetyl-CoA synthetase. (657 aa)
SIS67777.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
SIS67796.13-oxoacid CoA-transferase subunit B. (220 aa)
SIS67811.13-oxoacid CoA-transferase subunit A. (236 aa)
SIS67887.13-hydroxyacyl-CoA dehydrogenase. (306 aa)
SIS63102.1acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
SIS63125.1Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa)
SIS73013.1Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
SIS73162.1Acyl-CoA dehydrogenase. (584 aa)
SIS73890.1DNA-binding transcriptional regulator, MerR family. (123 aa)
SIS73907.1Acyl-CoA dehydrogenase. (530 aa)
SIS73923.1Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II. (533 aa)
SIS74372.1Hypothetical protein. (336 aa)
SIS74389.1CRISPR-associated endonuclease/helicase Cas3. (1008 aa)
SIS74402.1CRISPR-associated protein Csb2. (505 aa)
SIS74415.1CRISPR-associated protein, Csx4 family. (406 aa)
SIS74429.1Hypothetical protein. (70 aa)
SIS74472.12-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (290 aa)
SIS74499.1acyl-CoA thioester hydrolase. (133 aa)
SIS74508.1Adenine deaminase. (626 aa)
SIS74522.1benzoate-CoA ligase. (549 aa)
SIS74535.1Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
SIS74549.1Transcriptional regulator, PaaX family. (272 aa)
SIS74562.1Phenylacetic acid catabolic protein. (208 aa)
SIS74580.1Phenylacetic acid degradation B. (74 aa)
SIS74594.1phenylacetate-CoA oxygenase, PaaJ subunit. (103 aa)
SIS74610.1ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA. (317 aa)
SIS74678.14-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (335 aa)
SIS74695.1Uncharacterized conserved protein YgbK, DUF1537 family. (493 aa)
SIS74709.1DeoR C terminal sensor domain-containing protein. (126 aa)
SIS75126.1Uncharacterized oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (253 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (151 aa)
SIS79517.1Acyl-CoA dehydrogenase. (400 aa)
SIS79531.1Bacillithiol biosynthesis deacetylase BshB2. (230 aa)
SIS79544.1Protein of unknown function. (108 aa)
SIS79574.1Hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (275 aa)
SIS79587.1Hypothetical protein. (108 aa)
SIS77874.1Acetyl esterase/lipase. (298 aa)
SIS80214.1L-lactate dehydrogenase (cytochrome). (391 aa)
SIS80235.1fatty-acyl-CoA synthase. (559 aa)
SIS80473.1Hypothetical protein. (216 aa)
SIS80501.1Acyl-CoA synthetase (NDP forming). (637 aa)
SIS81350.1acrylyl-CoA reductase (NADPH). (333 aa)
SIS77778.1Nitroalkane oxidase. (367 aa)
SIS79142.1Enoyl-[acyl-carrier-protein] reductase [NADH]. (295 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (324 aa)
SIS85336.1SCP-2 sterol transfer family protein. (117 aa)
SIS85353.1Long-chain acyl-CoA synthetase. (508 aa)
SIS85372.1Hypothetical protein. (373 aa)
SIS85383.1acyl-CoA dehydrogenase. (402 aa)
SIS85399.1Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (268 aa)
SIS85415.13-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (280 aa)
SIS85431.1acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (379 aa)
SIS85464.1Sortase A. (208 aa)
SIS85479.1Ubiquinone biosynthesis protein. (566 aa)
SIS85489.1Hypothetical protein. (155 aa)
SIS85504.1Aldehyde dehydrogenase (acceptor). (510 aa)
SIS85556.1acyl-CoA dehydrogenase. (388 aa)
SIS85574.13-oxoacyl-[acyl-carrier protein] reductase. (253 aa)
SIS85589.1Gluconate 5-dehydrogenase. (257 aa)
SIS85605.1acyl-CoA dehydrogenase. (405 aa)
SIS85619.1fatty-acyl-CoA synthase. (544 aa)
SIS85635.1Acyl dehydratase. (151 aa)
SIS85652.1MaoC like domain-containing protein. (140 aa)
SIS85668.1Transcriptional regulator, IclR family. (257 aa)
SIS85700.1Predicted kinase, aminoglycoside phosphotransferase (APT) family. (355 aa)
SIS89644.1NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)
SIS89661.1acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
SIS89674.1acetyl-CoA synthetase. (549 aa)
SIS89685.1Enoyl-CoA hydratase/carnithine racemase. (356 aa)
SIS89704.1Methylmalonate-semialdehyde dehydrogenase [acylating]. (480 aa)
SIS89716.13-hydroxyisobutyrate dehydrogenase/2-hydroxy-3-oxopropionate reductase. (296 aa)
SIS89729.1Acyl-CoA dehydrogenase. (596 aa)
SIS89744.123S rRNA (cytosine1962-C5)-methyltransferase. (413 aa)
SIS89795.1Dipicolinate synthase subunit B. (200 aa)
SIS89806.1Dipicolinate synthase subunit A. (303 aa)
SIS89836.1Predicted Zn-dependent peptidase; Belongs to the peptidase M16 family. (422 aa)
SIS89854.1Probable sporulation protein, polysaccharide deacetylase family. (326 aa)
SIS91172.1acyl-CoA thioester hydrolase/thioesterase-3. (135 aa)
SIS92500.1Transcriptional regulator, DeoR family. (262 aa)
SIS94434.1Transcriptional regulator, TetR family. (202 aa)
SIS94452.1ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA. (311 aa)
SIS94469.1ring-1,2-phenylacetyl-CoA epoxidase subunit PaaB. (125 aa)
SIS94485.1ring-1,2-phenylacetyl-CoA epoxidase subunit PaaC. (262 aa)
SIS94503.1ring-1,2-phenylacetyl-CoA epoxidase subunit PaaD. (154 aa)
SIS94519.1phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (442 aa)
SIS94535.1Conserved hypothetical protein. (102 aa)
SIS94552.1Predicted thioesterase. (130 aa)
SIS94589.1Short chain enoyl-CoA hydratase /Enoyl-CoA hydratase. (257 aa)
SIS94606.13-oxoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
SIS94796.1Short chain enoyl-CoA hydratase. (255 aa)
SIS92690.1Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains. (398 aa)
SIS92703.1Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II. (509 aa)
SIS92718.1Foldase protein PrsA. (314 aa)
SIS93033.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (485 aa)
SIS97562.1Uncharacterized domain 1-containing protein. (138 aa)
SIS97581.1Long-chain acyl-CoA synthetase. (554 aa)
SIS97597.1Acyl-CoA dehydrogenase. (593 aa)
SIS97611.1acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
SIS97628.13-hydroxyacyl-CoA dehydrogenase. (797 aa)
SIS97641.1Fe-S oxidoreductase. (721 aa)
SIS97656.1Transcriptional regulator, TetR family. (198 aa)
SIS97670.1Electron transfer flavoprotein beta subunit. (252 aa)
SIS97686.1Electron transfer flavoprotein alpha subunit apoprotein. (327 aa)
SIT01082.1Transcriptional regulator, DeoR family. (203 aa)
plsXPhosphate:acyl-[acyl carrier protein] acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (344 aa)
SIT01124.1[acyl-carrier-protein] S-malonyltransferase. (319 aa)
SIT01143.13-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
acpP-2Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (79 aa)
SIT01182.13-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (413 aa)
SIS99204.1Transcriptional regulator, DeoR family. (260 aa)
SIS99834.13-hydroxybutyryl-CoA dehydrogenase. (296 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa)
SIT00071.13-oxoacyl-[acyl-carrier protein] reductase. (249 aa)
SIT03958.1NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family. (254 aa)
SIT05217.1Catalase; Belongs to the catalase family. (478 aa)
SIT08228.1Acetyl esterase/lipase. (286 aa)
SIT12040.1Predicted arabinose efflux permease, MFS family. (414 aa)
SIT13731.1acyl-CoA thioester hydrolase. (147 aa)
SIT13743.1Hypothetical protein. (137 aa)
SIT13757.13-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (241 aa)
SIT14491.1Hypothetical protein/cyclohexanecarboxyl-CoA dehydrogenase. (189 aa)
Your Current Organism:
Alicyclobacillus vulcanalis
NCBI taxonomy Id: 252246
Other names: A. vulcanalis, ATCC BAA-915, Alicyclobacillus vulcanalis Simbahan et al. 2004, Alicyclobacillus vulcanis, DSM 16176, strain CsHg2
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