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TIF6 TIF6 PV09_09588 PV09_09588 PV09_09518 PV09_09518 PV09_09159 PV09_09159 PV09_09175 PV09_09175 PV09_08935 PV09_08935 PV09_08885 PV09_08885 PV09_08900 PV09_08900 PV09_08743 PV09_08743 PV09_08433 PV09_08433 PV09_08343 PV09_08343 PV09_07575 PV09_07575 PV09_07078 PV09_07078 PV09_06814 PV09_06814 PV09_06535 PV09_06535 PV09_05826 PV09_05826 PV09_05726 PV09_05726 PV09_05481 PV09_05481 PV09_05102 PV09_05102 PV09_05179 PV09_05179 PV09_04821 PV09_04821 PV09_04870 PV09_04870 PV09_04519 PV09_04519 PV09_03539 PV09_03539 TIF35 TIF35 PV09_02719 PV09_02719 PV09_02640 PV09_02640 PV09_02102 PV09_02102 MEF1 MEF1 PV09_01789 PV09_01789 PV09_01811 PV09_01811 PV09_01267 PV09_01267 PV09_01364 PV09_01364 GUF1 GUF1 PV09_00573 PV09_00573 PV09_00694 PV09_00694 PV09_00929 PV09_00929 PV09_00295 PV09_00295 PV09_09342 PV09_09342 PV09_09327 PV09_09327 PV09_09172 PV09_09172 PV09_08213 PV09_08213 PV09_08075 PV09_08075 PV09_07592 PV09_07592 PV09_07566 PV09_07566 PV09_07469 PV09_07469 PV09_07164 PV09_07164 PV09_06855 PV09_06855 HCR1 HCR1 PV09_06753 PV09_06753 PV09_06612 PV09_06612 PV09_06404 PV09_06404 PV09_06179 PV09_06179 PV09_05867 PV09_05867 PV09_05968 PV09_05968 PV09_05505 PV09_05505 PV09_04169 PV09_04169 PV09_03646 PV09_03646 PV09_03464 PV09_03464 PV09_02748 PV09_02748 PV09_02840 PV09_02840 PV09_02326 PV09_02326 PV09_02548 PV09_02548 PV09_02567 PV09_02567 PV09_02593 PV09_02593 PV09_01962 PV09_01962 PV09_02177 PV09_02177 PV09_01649 PV09_01649 PV09_01015 PV09_01015 PV09_01215 PV09_01215 PV09_00006 PV09_00006 PV09_00088 PV09_00088 PV09_09626 PV09_09626 PV09_09015 PV09_09015 PV09_09274 PV09_09274 PV09_08842 PV09_08842 PV09_09057 PV09_09057 PV09_08511 PV09_08511 PV09_08499 PV09_08499 PV09_08527 PV09_08527 PV09_08102 PV09_08102 PV09_07890 PV09_07890 PV09_07505 PV09_07505 PV09_07547 PV09_07547 PV09_07457 PV09_07457 PV09_07769 PV09_07769 PV09_07349 PV09_07349 PV09_07426 PV09_07426 PV09_07436 PV09_07436 PV09_07283 PV09_07283 LSM1 LSM1 PRT1 PRT1 PV09_06875 PV09_06875 PV09_06568 PV09_06568 PV09_06792 PV09_06792 TIF34 TIF34 PV09_06484 PV09_06484 PV09_06201 PV09_06201 PV09_06167 PV09_06167 PV09_06040 PV09_06040 PV09_05953 PV09_05953 PV09_05688 PV09_05688 PV09_05692 PV09_05692 PV09_05553 PV09_05553 PV09_05412 PV09_05412 PV09_05426 PV09_05426 PV09_05605 PV09_05605 PV09_05038 PV09_05038 PV09_04936 PV09_04936 PV09_04468 PV09_04468 PV09_03967 PV09_03967 PV09_04284 PV09_04284 PV09_03760 PV09_03760 PV09_03221 PV09_03221 PV09_02798 PV09_02798 PV09_02980 PV09_02980 PV09_02419 PV09_02419 PV09_09165 PV09_09165 PV09_08997 PV09_08997 PV09_02624 PV09_02624 PV09_08808 PV09_08808 PV09_08116 PV09_08116 PV09_00954 PV09_00954 PV09_07806 PV09_07806 PV09_07863 PV09_07863 NIP1 NIP1 PV09_01346 PV09_01346 PV09_07475 PV09_07475 PV09_00815 PV09_00815 TIF32 TIF32 PV09_07095 PV09_07095 PV09_00136 PV09_00136 PV09_00911 PV09_00911 PV09_00278 PV09_00278 PV09_06760 PV09_06760 PV09_06782 PV09_06782 PV09_00396 PV09_00396 INT6 INT6 PV09_05900 PV09_05900 PV09_05948 PV09_05948 PV09_04844 PV09_04844 PV09_04563 PV09_04563 PAN2 PAN2 PAN3 PAN3 PV09_03737 PV09_03737 PV09_02055 PV09_02055 PV09_01246 PV09_01246 PV09_00807 PV09_00807 PV09_00870 PV09_00870
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (246 aa)
PV09_09588Uncharacterized protein. (547 aa)
PV09_09518SUI1 domain-containing protein. (638 aa)
PV09_09159Uncharacterized protein. (856 aa)
PV09_09175RF_PROK_I domain-containing protein. (191 aa)
PV09_08935W2 domain-containing protein. (425 aa)
PV09_08885Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (453 aa)
PV09_08900Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (489 aa)
PV09_08743S1-like domain-containing protein. (141 aa)
PV09_08433PUM-HD domain-containing protein. (971 aa)
PV09_08343Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (274 aa)
PV09_07575Uncharacterized protein. (266 aa)
PV09_07078Uncharacterized protein. (127 aa)
PV09_06814Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (462 aa)
PV09_06535Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (739 aa)
PV09_05826Uncharacterized protein. (251 aa)
PV09_05726Uncharacterized protein. (2677 aa)
PV09_05481Uncharacterized protein. (373 aa)
PV09_05102Uncharacterized protein. (725 aa)
PV09_05179RNase_PH domain-containing protein. (194 aa)
PV09_04821Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (573 aa)
PV09_04870Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (365 aa)
PV09_04519Uncharacterized protein. (288 aa)
PV09_03539Uncharacterized protein. (390 aa)
TIF35Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (288 aa)
PV09_02719Uncharacterized protein. (316 aa)
PV09_02640Uncharacterized protein. (1277 aa)
PV09_02102Uncharacterized protein. (583 aa)
MEF1Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (795 aa)
PV09_01789Uncharacterized protein; Belongs to the DEAD box helicase family. (598 aa)
PV09_0181140S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (191 aa)
PV09_01267Uncharacterized protein. (383 aa)
PV09_01364Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (481 aa)
GUF1Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (677 aa)
PV09_00573Uncharacterized protein. (362 aa)
PV09_00694Eukaryotic translation initiation factor 5A. (160 aa)
PV09_00929Uncharacterized protein. (623 aa)
PV09_00295Uncharacterized protein. (344 aa)
PV09_09342HTH La-type RNA-binding domain-containing protein. (1177 aa)
PV09_09327Uncharacterized protein. (407 aa)
PV09_09172PUM-HD domain-containing protein. (985 aa)
PV09_08213Tr-type G domain-containing protein. (642 aa)
PV09_08075HRDC domain-containing protein. (891 aa)
PV09_07592Zn(2)-C6 fungal-type domain-containing protein. (632 aa)
PV09_07566Fe2OG dioxygenase domain-containing protein. (642 aa)
PV09_074692-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (332 aa)
PV09_07164ATP-dependent RNA helicase DED1; Belongs to the DEAD box helicase family. (687 aa)
PV09_06855Eukaryotic translation initiation factor 2 subunit gamma. (504 aa)
HCR1Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (276 aa)
PV09_06753Uncharacterized protein. (326 aa)
PV09_06612Uncharacterized protein. (1156 aa)
PV09_06404Uncharacterized protein. (220 aa)
PV09_06179Uncharacterized protein. (606 aa)
PV09_05867SAM domain-containing protein. (607 aa)
PV09_05968DUF155 domain-containing protein. (467 aa)
PV09_05505Diphthami_syn_2 domain-containing protein. (775 aa)
PV09_04169Zn(2)-C6 fungal-type domain-containing protein. (508 aa)
PV09_03646Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (484 aa)
PV09_03464W2 domain-containing protein. (731 aa)
PV09_02748HABP4_PAI-RBP1 domain-containing protein. (343 aa)
PV09_02840Uncharacterized protein. (448 aa)
PV09_02326Protein kinase domain-containing protein. (741 aa)
PV09_02548Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (365 aa)
PV09_02567RRM domain-containing protein. (568 aa)
PV09_02593PUM-HD domain-containing protein. (718 aa)
PV09_01962Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (252 aa)
PV09_02177RWD domain-containing protein. (276 aa)
PV09_01649ECR1_N domain-containing protein. (346 aa)
PV09_01015Uncharacterized protein. (2256 aa)
PV09_01215HET domain-containing protein. (843 aa)
PV09_00006Uncharacterized protein. (1603 aa)
PV09_00088Uncharacterized protein. (1124 aa)
PV09_09626RBR-type E3 ubiquitin transferase. (664 aa)
PV09_090152-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily. (561 aa)
PV09_09274Fes1 domain-containing protein. (219 aa)
PV09_08842Guanine nucleotide-binding protein subunit beta-like protein. (316 aa)
PV09_09057Uncharacterized protein. (588 aa)
PV09_08511eIF2A domain-containing protein. (737 aa)
PV09_08499Uncharacterized protein. (535 aa)
PV09_08527ATP-dependent RNA helicase dhh1; Belongs to the DEAD box helicase family. (513 aa)
PV09_08102Translation initiation factor IF-2. (982 aa)
PV09_07890Woronin body major protein, variant. (234 aa)
PV09_07505Uncharacterized protein. (171 aa)
PV09_07547eIF2B_5 domain-containing protein. (459 aa)
PV09_0745760S ribosomal protein L16. (202 aa)
PV09_07769Eukaryotic peptide chain release factor subunit 1, variant. (435 aa)
PV09_07349Translation initiation factor RLI1. (604 aa)
PV09_07426Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (457 aa)
PV09_07436Uncharacterized protein. (320 aa)
PV09_07283Uncharacterized protein. (618 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (156 aa)
PRT1Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (732 aa)
PV09_06875Uncharacterized protein. (721 aa)
PV09_06568RRF domain-containing protein. (279 aa)
PV09_06792Tr-type G domain-containing protein. (702 aa)
TIF34Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (348 aa)
PV09_06484S4 RNA-binding domain-containing protein. (437 aa)
PV09_06201Uncharacterized protein. (141 aa)
PV09_06167Elongation factor 2. (840 aa)
PV09_06040Uncharacterized protein. (251 aa)
PV09_05953Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (246 aa)
PV09_05688Diphthine synthase. (286 aa)
PV09_05692MIT domain-containing protein. (1565 aa)
PV09_05553Uncharacterized protein. (583 aa)
PV09_05412UPF0029 domain-containing protein. (307 aa)
PV09_05426Uncharacterized protein. (172 aa)
PV09_05605RING-type domain-containing protein. (779 aa)
PV09_05038Nudix hydrolase domain-containing protein. (1045 aa)
PV09_04936ATP-dependent RNA helicase eIF4A; Belongs to the DEAD box helicase family. (397 aa)
PV09_04468NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (307 aa)
PV09_03967Uncharacterized protein. (572 aa)
PV09_04284Uncharacterized protein. (1396 aa)
PV09_03760LsmAD domain-containing protein. (1123 aa)
PV09_03221Uncharacterized protein. (278 aa)
PV09_02798Diphthamide biosynthesis protein 3. (80 aa)
PV09_02980RNase_PH domain-containing protein. (367 aa)
PV09_02419Uncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (228 aa)
PV09_09165PUM-HD domain-containing protein. (901 aa)
PV09_08997Uncharacterized protein. (973 aa)
PV09_02624Cell differentiation protein rcd1. (387 aa)
PV09_08808Translation machinery-associated protein 22. (192 aa)
PV09_08116Uncharacterized protein; Belongs to the DEAD box helicase family. (577 aa)
PV09_00954Ribosomal protein L13. (176 aa)
PV09_07806Uncharacterized protein. (299 aa)
PV09_07863Uncharacterized protein. (315 aa)
NIP1Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (865 aa)
PV09_01346MIF4G domain-containing protein. (1432 aa)
PV09_07475RF_PROK_I domain-containing protein. (468 aa)
PV09_00815Translation initiation factor aIF-2. (1103 aa)
TIF32Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1080 aa)
PV09_07095Telo_bind domain-containing protein. (1227 aa)
PV09_00136Uncharacterized protein. (489 aa)
PV09_00911S1 motif domain-containing protein. (309 aa)
PV09_00278Eukaryotic translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (150 aa)
PV09_06760PAT1 domain-containing protein. (844 aa)
PV09_06782Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (340 aa)
PV09_00396RNase_PH domain-containing protein. (346 aa)
INT6Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (432 aa)
PV09_05900RF_PROK_I domain-containing protein. (189 aa)
PV09_05948Uncharacterized protein. (761 aa)
PV09_04844RPOL4c domain-containing protein. (172 aa)
PV09_04563Tr-type G domain-containing protein. (568 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1165 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...] (648 aa)
PV09_03737Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (338 aa)
PV09_02055Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (354 aa)
PV09_01246Uncharacterized protein. (780 aa)
PV09_00807Uncharacterized protein. (1064 aa)
PV09_00870Uncharacterized protein. (635 aa)
Your Current Organism:
Verruconis gallopava
NCBI taxonomy Id: 253628
Other names: ATCC 16027, CBS 437.64, CDC 45-492-62, Dactylaria gallopava, MUCL 6683, Ochroconis gallopava, Scolecobasidium gallopavum, V. gallopava, Verruconis gallopava (W.B. Cooke) Samerpitak & de Hoog, 2014
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