(16 nodes) Synthesis and degradation of ketone bodies network (Verruconis gallopava)

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Your Input:
	PV09_07288	Uncharacterized protein. (212 aa)
	PV09_01333	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (458 aa)
	PV09_09535	Uncharacterized protein. (274 aa)
	PV09_09603	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (519 aa)
	PV09_04726	Uncharacterized protein. (282 aa)
	PV09_03398	Uncharacterized protein. (759 aa)
	PV09_06488	Pyruvate carboxyltransferase domain-containing protein. (139 aa)
	PV09_06184	Uncharacterized protein. (415 aa)
	PV09_04272	AB hydrolase-1 domain-containing protein. (552 aa)
	PV09_03239	Uncharacterized protein. (309 aa)
	PV09_01467	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (434 aa)
	PV09_01255	Fungal_trans domain-containing protein. (644 aa)
	PV09_00159	Uncharacterized protein. (290 aa)
	PV09_04735	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
	PV09_04356	Uncharacterized protein. (312 aa)
	PV09_02730	Pyruvate carboxyltransferase domain-containing protein. (366 aa)

Your Current Organism:

Verruconis gallopava

NCBI taxonomy Id: 253628
Other names: ATCC 16027, CBS 437.64, CDC 45-492-62, Dactylaria gallopava, MUCL 6683, Ochroconis gallopava, Scolecobasidium gallopavum, V. gallopava, Verruconis gallopava (W.B. Cooke) Samerpitak & de Hoog, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV09_00159	PV09_09603	A0A0D1Z8B5	A0A0D1X948	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.492
PV09_01255	PV09_01333	A0A0D1Z5U5	A0A0D2APF6	Fungal_trans domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.790
PV09_01255	PV09_01467	A0A0D1Z5U5	A0A0D1Z3K0	Fungal_trans domain-containing protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.665
PV09_01255	PV09_02730	A0A0D1Z5U5	A0A0D2AH59	Fungal_trans domain-containing protein.	Pyruvate carboxyltransferase domain-containing protein.	0.710
PV09_01255	PV09_03398	A0A0D1Z5U5	A0A0D1XS48	Fungal_trans domain-containing protein.	Uncharacterized protein.	0.665
PV09_01255	PV09_04735	A0A0D1Z5U5	A0A0D2ABE8	Fungal_trans domain-containing protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.665
PV09_01255	PV09_06184	A0A0D1Z5U5	A0A0D1YNT4	Fungal_trans domain-containing protein.	Uncharacterized protein.	0.665
PV09_01255	PV09_06488	A0A0D1Z5U5	A0A0D1YNR6	Fungal_trans domain-containing protein.	Pyruvate carboxyltransferase domain-containing protein.	0.710
PV09_01333	PV09_01255	A0A0D2APF6	A0A0D1Z5U5	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Fungal_trans domain-containing protein.	0.790
PV09_01333	PV09_01467	A0A0D2APF6	A0A0D1Z3K0	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.978
PV09_01333	PV09_02730	A0A0D2APF6	A0A0D2AH59	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Pyruvate carboxyltransferase domain-containing protein.	0.794
PV09_01333	PV09_03398	A0A0D2APF6	A0A0D1XS48	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.969
PV09_01333	PV09_04272	A0A0D2APF6	A0A0D1YV60	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	AB hydrolase-1 domain-containing protein.	0.622
PV09_01333	PV09_04735	A0A0D2APF6	A0A0D2ABE8	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.985
PV09_01333	PV09_06184	A0A0D2APF6	A0A0D1YNT4	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.960
PV09_01333	PV09_06488	A0A0D2APF6	A0A0D1YNR6	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Pyruvate carboxyltransferase domain-containing protein.	0.794
PV09_01333	PV09_09603	A0A0D2APF6	A0A0D1X948	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.879
PV09_01467	PV09_01255	A0A0D1Z3K0	A0A0D1Z5U5	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Fungal_trans domain-containing protein.	0.665
PV09_01467	PV09_01333	A0A0D1Z3K0	A0A0D2APF6	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.978
PV09_01467	PV09_02730	A0A0D1Z3K0	A0A0D2AH59	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Pyruvate carboxyltransferase domain-containing protein.	0.777

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