(94 nodes) Valine, leucine and isoleucine degradation network (Verruconis gallopava)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV09_03251	Acetoacetate-CoA ligase. (685 aa)
	PV09_00094	Uncharacterized protein. (453 aa)
	PV09_01529	APH domain-containing protein. (369 aa)
	PV09_01899	Uncharacterized protein. (433 aa)
	PV09_02920	Uncharacterized protein. (566 aa)
	PV09_03348	Dihydrolipoyl dehydrogenase. (508 aa)
	PV09_04461	Uncharacterized protein. (575 aa)
	PV09_04447	APH domain-containing protein. (379 aa)
	PV09_05962	Uncharacterized protein. (687 aa)
	PV09_05846	Uncharacterized protein. (300 aa)
	PV09_06478	SET domain-containing protein. (384 aa)
	PV09_06365	APH domain-containing protein. (854 aa)
	PV09_00940	Uncharacterized protein. (264 aa)
	PV09_06839	Zn(2)-C6 fungal-type domain-containing protein. (736 aa)
	PV09_07133	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (419 aa)
	PV09_00556	Uncharacterized protein. (443 aa)
	PV09_00533	Uncharacterized protein. (299 aa)
	PV09_01333	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (458 aa)
	PV09_01418	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (486 aa)
	PV09_07662	Cytochrome b5 heme-binding domain-containing protein. (510 aa)
	PV09_07993	Uncharacterized protein. (328 aa)
	PV09_08335	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (513 aa)
	PV09_08450	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (508 aa)
	PV09_02066	Aldedh domain-containing protein. (511 aa)
	PV09_08783	Ion_trans domain-containing protein. (1153 aa)
	PV09_09785	Aldedh domain-containing protein. (123 aa)
	PV09_09603	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (519 aa)
	PV09_08662	Importin N-terminal domain-containing protein. (955 aa)
	PV09_08538	3-hydroxyisobutyrate dehydrogenase. (320 aa)
	PV09_07925	Uncharacterized protein. (708 aa)
	PV09_07362	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (274 aa)
	PV09_06636	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
	PV09_05512	Uncharacterized protein. (212 aa)
	PV09_04837	Mercuric reductase. (501 aa)
	PV09_04963	Uncharacterized protein. (533 aa)
	PV09_04551	Zn(2)-C6 fungal-type domain-containing protein. (675 aa)
	PV09_03398	Uncharacterized protein. (759 aa)
	PV09_02302	Uncharacterized protein. (436 aa)
	PV09_02620	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (419 aa)
	PV09_02207	Acetoacetate-CoA ligase. (700 aa)
	PV09_01785	Uncharacterized protein. (443 aa)
	PV09_00653	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (416 aa)
	PV09_00709	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (478 aa)
	PV09_00158	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (487 aa)
	PV09_00488	Uncharacterized protein. (464 aa)
	PV09_08972	Uncharacterized protein. (272 aa)
	PV09_08443	Uncharacterized protein. (433 aa)
	PV09_06977	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (291 aa)
	PV09_06701	3-hydroxyisobutyrate dehydrogenase. (340 aa)
	PV09_06488	Pyruvate carboxyltransferase domain-containing protein. (139 aa)
	PV09_06184	Uncharacterized protein. (415 aa)
	PV09_06145	Zn(2)-C6 fungal-type domain-containing protein. (765 aa)
	PV09_05643	Uncharacterized protein. (608 aa)
	PV09_04272	AB hydrolase-1 domain-containing protein. (552 aa)
	PV09_03649	APH domain-containing protein. (363 aa)
	PV09_03478	Uncharacterized protein. (491 aa)
	PV09_02136	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (557 aa)
	PV09_01467	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (434 aa)
	PV09_01667	Methylmalonate-semialdehyde dehydrogenase (Acylating). (571 aa)
	PV09_01255	Fungal_trans domain-containing protein. (644 aa)
	PV09_01260	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (413 aa)
	PV09_00092	APH domain-containing protein. (373 aa)
	PV09_09413	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (497 aa)
	PV09_09360	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (489 aa)
	PV09_09536	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (488 aa)
	PV09_09432	Transket_pyr domain-containing protein. (401 aa)
	PV09_08777	Uncharacterized protein. (715 aa)
	PV09_08909	Homoserine O-acetyltransferase. (557 aa)
	PV09_08884	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (503 aa)
	PV09_08680	APH domain-containing protein. (366 aa)
	PV09_08557	Uncharacterized protein. (451 aa)
	PV09_08265	Aldedh domain-containing protein. (487 aa)
	PV09_08113	Uncharacterized protein. (594 aa)
	PV09_07008	Cytochrome b5 heme-binding domain-containing protein. (553 aa)
	PV09_06911	Branched-chain amino acid aminotransferase. (379 aa)
	PV09_06610	Uncharacterized protein. (453 aa)
	PV09_06136	Acetoacetate-CoA ligase. (673 aa)
	PV09_05750	Zn(2)-C6 fungal-type domain-containing protein. (752 aa)
	PV09_05213	Uncharacterized protein. (498 aa)
	PV09_05144	Acetoacetate-CoA ligase. (686 aa)
	PV09_04735	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
	PV09_04657	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (467 aa)
	PV09_04670	Uncharacterized protein. (441 aa)
	PV09_04714	Uncharacterized protein. (582 aa)
	PV09_04649	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (509 aa)
	PV09_04092	3-hydroxyisobutyrate dehydrogenase. (338 aa)
	PV09_04462	Uncharacterized protein. (459 aa)
	PV09_03912	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (424 aa)
	PV09_04094	Methylmalonate-semialdehyde dehydrogenase (Acylating). (525 aa)
	PV09_03758	Uncharacterized protein. (435 aa)
	PV09_03339	Uncharacterized protein. (319 aa)
	PV09_02694	Uncharacterized protein. (442 aa)
	PV09_02730	Pyruvate carboxyltransferase domain-containing protein. (366 aa)
	PV09_01917	Uncharacterized protein. (601 aa)

Your Current Organism:

Verruconis gallopava

NCBI taxonomy Id: 253628
Other names: ATCC 16027, CBS 437.64, CDC 45-492-62, Dactylaria gallopava, MUCL 6683, Ochroconis gallopava, Scolecobasidium gallopavum, V. gallopava, Verruconis gallopava (W.B. Cooke) Samerpitak & de Hoog, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV09_00092	PV09_00094	A0A0D1Z866	A0A0D2BCP1	APH domain-containing protein.	Uncharacterized protein.	0.905
PV09_00092	PV09_00488	A0A0D1Z866	A0A0D1Y3W8	APH domain-containing protein.	Uncharacterized protein.	0.909
PV09_00092	PV09_00556	A0A0D1Z866	A0A0D2AQ27	APH domain-containing protein.	Uncharacterized protein.	0.464
PV09_00092	PV09_01785	A0A0D1Z866	A0A0D1XYJ0	APH domain-containing protein.	Uncharacterized protein.	0.402
PV09_00092	PV09_02694	A0A0D1Z866	A0A0D2AH23	APH domain-containing protein.	Uncharacterized protein.	0.908
PV09_00092	PV09_03339	A0A0D1Z866	A0A0D2AG25	APH domain-containing protein.	Uncharacterized protein.	0.464
PV09_00092	PV09_04461	A0A0D1Z866	A0A0D2B028	APH domain-containing protein.	Uncharacterized protein.	0.494
PV09_00092	PV09_04462	A0A0D1Z866	A0A0D2AE38	APH domain-containing protein.	Uncharacterized protein.	0.402
PV09_00092	PV09_04670	A0A0D1Z866	A0A0D2AC12	APH domain-containing protein.	Uncharacterized protein.	0.912
PV09_00092	PV09_04735	A0A0D1Z866	A0A0D2ABE8	APH domain-containing protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.441
PV09_00092	PV09_07362	A0A0D1Z866	A0A0D1XFW1	APH domain-containing protein.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.420
PV09_00092	PV09_07925	A0A0D1Z866	A0A0D1XEG9	APH domain-containing protein.	Uncharacterized protein.	0.506
PV09_00092	PV09_08557	A0A0D1Z866	A0A0D2A0R5	APH domain-containing protein.	Uncharacterized protein.	0.440
PV09_00092	PV09_08884	A0A0D1Z866	A0A0D1ZZI6	APH domain-containing protein.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.444
PV09_00092	PV09_09360	A0A0D1Z866	A0A0D1ZWQ7	APH domain-containing protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.407
PV09_00094	PV09_00092	A0A0D2BCP1	A0A0D1Z866	Uncharacterized protein.	APH domain-containing protein.	0.905
PV09_00094	PV09_00488	A0A0D2BCP1	A0A0D1Y3W8	Uncharacterized protein.	Uncharacterized protein.	0.786
PV09_00094	PV09_00556	A0A0D2BCP1	A0A0D2AQ27	Uncharacterized protein.	Uncharacterized protein.	0.812
PV09_00094	PV09_00653	A0A0D2BCP1	A0A0D1Y0U3	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.807
PV09_00094	PV09_01260	A0A0D2BCP1	A0A0D1Z5U9	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.807

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