(91 nodes) Mixed, incl. Purine nucleobase metabolic process, and Molybdenum ion binding network (Streptomyces sp. C)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EFL13149.1	Conserved hypothetical protein; Truncated CDS. (283 aa)
	EFL13150.1	4-hydroxybenzoyl-CoA reductase, beta subunit. (330 aa)
	EFL13151.1	4-hydroxybenzoyl-CoA reductase, gamma subunit. (163 aa)
	EFL13183.1	Xanthine dehydrogenase accessory protein XdhC. (272 aa)
	EFL13184.1	Xanthine dehydrogenase. (64 aa)
	EFL13185.1	Xanthine dehydrogenase, molybdopterin binding subunit. (695 aa)
	EFL13186.1	Predicted protein. (236 aa)
	EFL13187.1	Predicted protein. (373 aa)
	EFL13189.1	Predicted protein. (156 aa)
	EFL13190.1	Conserved hypothetical protein. (236 aa)
	EFL13464.1	Conserved hypothetical protein. (285 aa)
	EFL13465.1	Predicted protein. (259 aa)
	EFL13466.1	Oxidoreductase. (250 aa)
	EFL13467.1	Xanthine dehydrogenase subunit. (275 aa)
	EFL13468.1	4-hydroxybenzoyl-CoA reductase, alpha subunit. (908 aa)
	EFL13469.1	Conserved hypothetical protein. (323 aa)
	EFL13512.1	4-hydroxybenzoyl-CoA reductase, gamma subunit. (151 aa)
	EFL13513.1	Predicted protein. (743 aa)
	EFL13619.1	Conserved hypothetical protein; Belongs to the HpcH/HpaI aldolase family. (432 aa)
	EFL13638.1	Secreted protein. (495 aa)
	EFL13639.1	Lipoprotein. (218 aa)
	EFL13640.1	NADPH-ferredoxin reductase. (458 aa)
	EFL13822.1	Conserved hypothetical protein. (149 aa)
	EFL13823.1	Conserved hypothetical protein. (275 aa)
	EFL13906.1	Predicted protein. (283 aa)
	EFL13907.1	Predicted protein. (280 aa)
	EFL14033.1	Carbon-monoxide dehydrogenase, large subunit. (803 aa)
	EFL14034.1	Xanthine dehydrogenase E subunit. (175 aa)
	EFL14695.1	Conserved hypothetical protein. (189 aa)
	EFL14841.1	Secreted protein. (205 aa)
	EFL14974.1	Dehydrogenase. (297 aa)
	EFL15074.1	Conserved hypothetical protein. (77 aa)
	EFL15075.1	Alpha-ribazole phosphatase; Belongs to the phosphoglycerate mutase family. (220 aa)
	EFL15077.1	Membrane protein. (547 aa)
	EFL15079.1	Membrane protein. (55 aa)
	EFL15080.1	Peptidase M48. (384 aa)
	EFL15187.1	Predicted protein. (225 aa)
	EFL15259.1	Conserved hypothetical protein. (303 aa)
	EFL15447.1	Xanthine dehydrogenase D subunit. (771 aa)
	EFL15448.1	Conserved hypothetical protein. (429 aa)
	EFL15449.1	Dehydrogenase. (246 aa)
	EFL15665.1	Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (277 aa)
	EFL15791.1	Dehydrogenase. (298 aa)
	EFL15792.1	Transcriptional regulator. (138 aa)
	EFL15793.1	Conserved hypothetical protein. (245 aa)
	EFL16035.1	Cytosine deaminase. (431 aa)
	EFL16165.1	Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. (305 aa)
	EFL16552.1	Pyrroline-5-carboxylate reductase. (303 aa)
	EFL16934.1	Hydrolase. (421 aa)
	EFL17110.1	OHCU decarboxylase. (206 aa)
	EFL17207.1	Integral membrane protein. (226 aa)
	EFL17209.1	Predicted protein. (84 aa)
	EFL17363.1	Xanthine dehydrogenase D subunit. (796 aa)
	EFL17620.1	Xanthine and CO dehydrogenase maturation factor; Truncated CDS; unextendable partial coding region. (256 aa)
	EFL18174.1	Putative isomerase; Unextendable partial coding region. (300 aa)
	EFL18175.1	Conserved hypothetical protein. (227 aa)
	EFL18176.1	Metal dependent hydrolase. (285 aa)
	EFL18177.1	Type I phosphodiesterase/nucleotide pyrophosphatase. (430 aa)
	EFL18349.1	Dehydrogenase. (297 aa)
	EFL18350.1	4-hydroxybenzoyl-CoA reductase, gamma subunit. (199 aa)
	EFL18351.1	Xanthine dehydrogenase D subunit. (799 aa)
	EFL18353.1	Xanthine dehydrogenase accessory factor. (383 aa)
	EFL18449.1	Conserved hypothetical protein. (239 aa)
	EFL18450.1	Glyoxylate carboligase; Belongs to the TPP enzyme family. (595 aa)
	EFL18451.1	Predicted protein. (126 aa)
	EFL18457.1	2-hydroxy-3-oxopropionate reductase. (296 aa)
	EFL18458.1	Hydroxypyruvate isomerase; Belongs to the hyi family. (277 aa)
	EFL18459.1	Conserved hypothetical protein. (83 aa)
	EFL18460.1	DNA-binding protein. (134 aa)
	EFL18461.1	OHCU decarboxylase. (171 aa)
	EFL18462.1	Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (129 aa)
	EFL18463.1	Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. (307 aa)
	EFL18464.1	Imidazolonepropionase. (467 aa)
	EFL18474.1	YgfJ family molybdenum hydroxylase accessory protein. (193 aa)
	EFL18482.1	Allantoinase. (426 aa)
	alc	Allantoicase; Belongs to the allantoicase family. (375 aa)
	EFL18541.1	Glycerate kinase; Belongs to the glycerate kinase type-1 family. (382 aa)
	EFL18757.1	Lipoprotein. (189 aa)
	EFL19240.1	Predicted protein. (97 aa)
	EFL19241.1	Urate catabolism protein. (312 aa)
	EFL19243.1	Transcriptional regulator. (190 aa)
	EFL19510.1	DNA-binding protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (114 aa)
	EFL19762.1	Predicted protein. (74 aa)
	EFL19763.1	Predicted protein. (181 aa)
	EFL19764.1	Conserved hypothetical protein. (180 aa)
	EFL19766.1	Hypothetical protein. (159 aa)
	EFL19988.1	Predicted protein. (262 aa)
	EFL20272.1	TetR family transcriptional regulator. (206 aa)
	EFL20274.1	Conserved hypothetical protein. (231 aa)
	EFL20276.1	Predicted protein. (193 aa)
	EFL20277.1	Predicted protein. (91 aa)

Your Current Organism:

Streptomyces sp. C

NCBI taxonomy Id: 253839
Other names: S. sp. C

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFL13149.1	EFL13150.1	SSNG_00401	SSNG_00402	Conserved hypothetical protein; Truncated CDS.	4-hydroxybenzoyl-CoA reductase, beta subunit.	0.997
EFL13149.1	EFL13151.1	SSNG_00401	SSNG_00403	Conserved hypothetical protein; Truncated CDS.	4-hydroxybenzoyl-CoA reductase, gamma subunit.	0.996
EFL13149.1	EFL13185.1	SSNG_00401	SSNG_00437	Conserved hypothetical protein; Truncated CDS.	Xanthine dehydrogenase, molybdopterin binding subunit.	0.863
EFL13149.1	EFL13186.1	SSNG_00401	SSNG_00438	Conserved hypothetical protein; Truncated CDS.	Predicted protein.	0.938
EFL13149.1	EFL13189.1	SSNG_00401	SSNG_00441	Conserved hypothetical protein; Truncated CDS.	Predicted protein.	0.485
EFL13149.1	EFL13467.1	SSNG_00401	SSNG_00719	Conserved hypothetical protein; Truncated CDS.	Xanthine dehydrogenase subunit.	0.853
EFL13149.1	EFL13468.1	SSNG_00401	SSNG_00720	Conserved hypothetical protein; Truncated CDS.	4-hydroxybenzoyl-CoA reductase, alpha subunit.	0.835
EFL13149.1	EFL13512.1	SSNG_00401	SSNG_00764	Conserved hypothetical protein; Truncated CDS.	4-hydroxybenzoyl-CoA reductase, gamma subunit.	0.965
EFL13149.1	EFL14034.1	SSNG_00401	SSNG_01286	Conserved hypothetical protein; Truncated CDS.	Xanthine dehydrogenase E subunit.	0.967
EFL13149.1	EFL15448.1	SSNG_00401	SSNG_02700	Conserved hypothetical protein; Truncated CDS.	Conserved hypothetical protein.	0.959
EFL13149.1	EFL15449.1	SSNG_00401	SSNG_02701	Conserved hypothetical protein; Truncated CDS.	Dehydrogenase.	0.921
EFL13149.1	EFL16165.1	SSNG_00401	SSNG_03417	Conserved hypothetical protein; Truncated CDS.	Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.	0.863
EFL13149.1	EFL17620.1	SSNG_00401	SSNG_04872	Conserved hypothetical protein; Truncated CDS.	Xanthine and CO dehydrogenase maturation factor; Truncated CDS; unextendable partial coding region.	0.830
EFL13149.1	EFL18349.1	SSNG_00401	SSNG_05601	Conserved hypothetical protein; Truncated CDS.	Dehydrogenase.	0.923
EFL13149.1	EFL18350.1	SSNG_00401	SSNG_05602	Conserved hypothetical protein; Truncated CDS.	4-hydroxybenzoyl-CoA reductase, gamma subunit.	0.967
EFL13149.1	EFL18353.1	SSNG_00401	SSNG_05605	Conserved hypothetical protein; Truncated CDS.	Xanthine dehydrogenase accessory factor.	0.906
EFL13149.1	EFL18463.1	SSNG_00401	SSNG_05715	Conserved hypothetical protein; Truncated CDS.	Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.	0.902
EFL13149.1	EFL18464.1	SSNG_00401	SSNG_05716	Conserved hypothetical protein; Truncated CDS.	Imidazolonepropionase.	0.485
EFL13149.1	EFL18474.1	SSNG_00401	SSNG_05726	Conserved hypothetical protein; Truncated CDS.	YgfJ family molybdenum hydroxylase accessory protein.	0.820
EFL13150.1	EFL13149.1	SSNG_00402	SSNG_00401	4-hydroxybenzoyl-CoA reductase, beta subunit.	Conserved hypothetical protein; Truncated CDS.	0.997