(18 nodes) Mixed, incl. rRNA processing, and tRNA processing network (Streptomyces sp. C)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EFL14864.1	2-deoxy-D-gluconate 3-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (270 aa)
	EFL14865.1	Major facilitator superfamily transporter permease. (443 aa)
	EFL14866.1	Conserved hypothetical protein. (343 aa)
	era	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (316 aa)
	EFL15043.1	Conserved hypothetical protein. (125 aa)
	EFL15044.1	MmcQ. (117 aa)
	EFL15045.1	CBS domain-containing protein. (435 aa)
	ybeY	Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (165 aa)
	EFL15047.1	Phosphate starvation-induced protein. (356 aa)
	EFL15048.1	Carbohydrate kinase. (387 aa)
	rnz	Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (304 aa)
	EFL15050.1	Hit-family protein. (119 aa)
	EFL15051.1	Involving differentiation; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (289 aa)
	EFL15052.1	Dioxygenase. (366 aa)
	EFL15055.1	Metallo-beta-lactamase. (243 aa)
	EFL15056.1	Conserved hypothetical protein. (269 aa)
	EFL16770.1	Conserved hypothetical protein. (278 aa)
	truA	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (287 aa)

Your Current Organism:

Streptomyces sp. C

NCBI taxonomy Id: 253839
Other names: S. sp. C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFL14864.1	EFL14865.1	SSNG_02116	SSNG_02117	2-deoxy-D-gluconate 3-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Major facilitator superfamily transporter permease.	0.754
EFL14864.1	EFL14866.1	SSNG_02116	SSNG_02118	2-deoxy-D-gluconate 3-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Conserved hypothetical protein.	0.751
EFL14865.1	EFL14864.1	SSNG_02117	SSNG_02116	Major facilitator superfamily transporter permease.	2-deoxy-D-gluconate 3-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.754
EFL14865.1	EFL14866.1	SSNG_02117	SSNG_02118	Major facilitator superfamily transporter permease.	Conserved hypothetical protein.	0.890
EFL14866.1	EFL14864.1	SSNG_02118	SSNG_02116	Conserved hypothetical protein.	2-deoxy-D-gluconate 3-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.751
EFL14866.1	EFL14865.1	SSNG_02118	SSNG_02117	Conserved hypothetical protein.	Major facilitator superfamily transporter permease.	0.890
EFL14866.1	EFL15055.1	SSNG_02118	SSNG_02307	Conserved hypothetical protein.	Metallo-beta-lactamase.	0.434
EFL14866.1	EFL16770.1	SSNG_02118	SSNG_04022	Conserved hypothetical protein.	Conserved hypothetical protein.	0.796
EFL14866.1	era	SSNG_02118	SSNG_02290	Conserved hypothetical protein.	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.939
EFL14866.1	truA	SSNG_02118	SSNG_04243	Conserved hypothetical protein.	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.905
EFL14866.1	ybeY	SSNG_02118	SSNG_02298	Conserved hypothetical protein.	Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.896
EFL15043.1	EFL15044.1	SSNG_02295	SSNG_02296	Conserved hypothetical protein.	MmcQ.	0.745
EFL15043.1	EFL15045.1	SSNG_02295	SSNG_02297	Conserved hypothetical protein.	CBS domain-containing protein.	0.761
EFL15043.1	EFL15047.1	SSNG_02295	SSNG_02299	Conserved hypothetical protein.	Phosphate starvation-induced protein.	0.873
EFL15043.1	EFL15048.1	SSNG_02295	SSNG_02300	Conserved hypothetical protein.	Carbohydrate kinase.	0.769
EFL15043.1	EFL15050.1	SSNG_02295	SSNG_02302	Conserved hypothetical protein.	Hit-family protein.	0.601
EFL15043.1	era	SSNG_02295	SSNG_02290	Conserved hypothetical protein.	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.921
EFL15043.1	rnz	SSNG_02295	SSNG_02301	Conserved hypothetical protein.	Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.	0.604
EFL15043.1	ybeY	SSNG_02295	SSNG_02298	Conserved hypothetical protein.	Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.953
EFL15044.1	EFL15043.1	SSNG_02296	SSNG_02295	MmcQ.	Conserved hypothetical protein.	0.745