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cspA cspA BP1798 BP1798 iscS iscS iscU iscU iscA iscA hscB hscB hscA hscA fdx fdx BP1805 BP1805 BP1842 BP1842 BP1843 BP1843 BP1844 BP1844 BP1845 BP1845 mltG mltG BP1849 BP1849 erpA erpA BP2959 BP2959 cyaY cyaY
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cspACold shock protein; Similar to Escherichia coli cold shock protein CspA or B3556 SW:CSPA_ECOLI (P15277) (69 aa) fasta scores: E(): 9.5e-12, 55.385% id in 65 aa, and to Bordetella pertussis cold shock-like protein CspA SW:CSPA_BORPE (Q9Z5R4) (67 aa) fasta scores: E(): 2.9e-16, 68.657% id in 67 aa. Also similar to BP1770 (68.657% identity in 67 aa overlap), BP1772 (71.186% identity in 59 aa overlap), BP2757 (61.905% identity in 63 aa overlap), and to BP3871 (54.545% identity in 66 aa overlap). (67 aa)
BP1798Putative DNA-binding protein; Similar to Ralstonia solanacearum conserved hypothetical protein Rsc1018 TR:CAD14720 (EMBL:AL646062) (193 aa) fasta scores: E(): 9.9e-42, 70.58% id in 170 aa, and to Neisseria meningitidis hypothetical protein Nma1593/Nmb1378 precursor Nma1593 or Nmb1378 SW:YF93_NEIMA (Q51134) (148 aa) fasta scores: E(): 6.3e-28, 60.87% id in 138 aa. (170 aa)
iscSCysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (403 aa)
iscU[Fe-S] cluster formation/repair protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (136 aa)
iscA[Fe-S] cluster formation/repair protein; Similar to Azotobacter vinelandii IscA TR:O31271 (EMBL:AF010139) (107 aa) fasta scores: E(): 1.5e-28, 68.22% id in 107 aa, and to Pseudomonas aeruginosa probable iron-binding protein isca isca or pa3812 TR:Q9HXJ0 (EMBL:AE004799) (107 aa) fasta scores: E(): 1.5e-29, 71.02% id in 107 aa. Also similar to BP2958, 39.623% identity (40.000% ungapped) in 106 aa overlap; Belongs to the HesB/IscA family. (107 aa)
hscBChaperone protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (170 aa)
hscAChaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (620 aa)
fdxFerredoxin, 2Fe-2S; Similar to Escherichia coli ferredoxin, 2Fe-2S Fdx or B2525 or Z3792 or Ecs3391 TR:AAG57639 (EMBL:M88654) (111 aa) fasta scores: E(): 1.5e-28, 62.5% id in 112 aa, and to Neisseria meningitidis putative ferredoxin Fdx or Nma1344 or Nmb1172 TR:Q9JQT7 (EMBL:AL162755) (113 aa) fasta scores: E(): 7.3e-33, 67.25% id in 113 aa. Also similar to BP3174, 63.964% identity (64.545% ungapped) in 111 aa overlap. (113 aa)
BP1805Conserved hypothetical protein; Similar to Azotobacter vinelandii hypothetical 7.9 kDa protein TR:O69223 (EMBL:AF010139) (68 aa) fasta scores: E(): 1.3e-14, 62.5% id in 64 aa, and to Neisseria meningitidis hypothetical protein Nma1347 or Nmb1175 TR:Q9JR02 (EMBL:AL162755) (65 aa) fasta scores: E(): 9.5e-14, 60% id in 65 aa. (64 aa)
BP1842Probable class-V aminotransferase; Similar to Escherichia coli selenocysteine lyase CsdB or SufS or B1680 SW:CSDB_ECOLI (P77444) (406 aa) fasta scores: E(): 1.3e-18, 29.57% id in 355 aa, and to Streptomyces capreolus capreomycin acetyltransferase Cac TR:Q53824 (EMBL:U13077) (359 aa) fasta scores: E(): 8.9e-38, 39.33% id in 361 aa. (402 aa)
BP1843Similar to Rhizobium meliloti hypothetical protein Smc02103 TR:CAC46072 (EMBL:AL591787) (154 aa) fasta scores: E(): 2.4e-22, 50% id in 156 aa, and to Agrobacterium tumefaciens strC58 Agr_c_2535p TR:AAK87164 (EMBL:AE008063) (156 aa) fasta scores: E(): 8.6e-21, 46.75% id in 154 aa. (157 aa)
BP1844Transposase for IS481 element. (316 aa)
BP1845Conserved hypothetical protein; Similar to Escherichia coli unknown protein from 2D-PAGE YgfZ or B2898 SW:UP14_ECOLI (P39179) (325 aa) fasta scores: E(): 7.2e-17, 31.3% id in 345 aa, and to Pseudomonas aeruginosa hypothetical protein Pa0759 TR:Q9I5H0 (EMBL:AE004511) (314 aa) fasta scores: E(): 1.6e-13, 32.91% id in 316 aa. (338 aa)
mltGPutative exported protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (344 aa)
BP1849Similar to Neisseria meningitidis hypothetical protein Nmb0771 TR:Q9K050 (EMBL:AE002431) (259 aa) fasta scores: E(): 1.5e-44, 50% id in 252 aa, and to Vibrio cholerae hypothetical protein Vc2014 TR:Q9KQI4 (EMBL:AE004276) (255 aa) fasta scores: E(): 1.7e-43, 49.8% id in 255 aa. (256 aa)
erpAConserved hypothetical protein; Required for insertion of 4Fe-4S clusters. (123 aa)
BP2959Putative integral membrane protein; Weakly similar in parts to Pseudomonas aeruginosa hypothetical protein Pa0663 TR:Q9I5Q8 (EMBL:AE004501) (239 aa) fasta scores: E(): 9.1e-06, 28.82% id in 222 aa. (248 aa)
cyaYConserved hypothetical protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (109 aa)
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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