STRINGSTRING
cheA cheA cheW cheW tsr tsr cheB cheB tsr-2 tsr-2 cheD cheD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cheAChemotaxis protein CheY (Pseudogene); HMMPfam hit to PF00072, Response regulator receiver domain. (685 aa)
cheWSimilar to Escherichia coli chemotaxis protein CheW or B1887 or Z2941 or Ecs2597 SW:CHEW_ECOLI (P07365) (167 aa) fasta scores: E(): 1.3e-41, 74.83% id in 155 aa, and to Burkholderia pseudomallei (Pseudomonas pseudomallei) chemotaxis protein CheW TR:O05183 (EMBL:U92493) (175 aa) fasta scores: E(): 7e-43, 72.56% id in 164 aa. (166 aa)
tsrSimilar to Escherichia coli methyl-accepting chemotaxis protein I Tsr or CheD or B4355 SW:MCP1_ECOLI (P02942) (551 aa) fasta scores: E(): 3e-64, 46.71% id in 533 aa, and to Salmonella typhimurium methyl-accepting chemotaxis protein II TaR SW:MCP2_SALTY (P02941) (553 aa) fasta scores: E(): 1.2e-63, 45.87% id in 558 aa. Also similar to BP1384 (64.476% identity in 563 aa overlap), BP1385 (61.649% identity in 558 aa overlap), BP2268 (56.415% identity in 491 aa overlap), and to BP1591 (44.216% identity in 536 aa overlap). (568 aa)
cheBChemotaxis protein methyltransferase (Pseudogene); Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (350 aa)
tsr-2Similar to Escherichia coli methyl-accepting chemotaxis protein I Tsr or Ched or B4355 SW:MCP1_ECOLI (P02942) (551 aa) fasta scores: E(): 1.4e-54, 46.18% id in 550 aa, and to Escherichia coli methyl-accepting chemotaxis protein II Tar or Chem or B1886 SW:MCP2_ECOLI (P07017) (553 aa) fasta scores: E(): 1.3e-53, 45.24% id in 557 aa. (606 aa)
cheDConserved hypothetical protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family. (215 aa)
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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