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flgE flgE BP0337 BP0337 ycgR ycgR motA motA motB motB cheZ cheZ flgB flgB flgC flgC flgF flgF flgG flgG flgH flgH flgI flgI flgL flgL fliN fliN fliM fliM fliL fliL fliJ fliJ fliI fliI fliH fliH fliG fliG fliF fliF fliE fliE BP1405 BP1405 bscQ bscQ bscN bscN mar mar
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
flgESimilar to Salmonella typhimurium flagellar hook protein FlgE or FlaK or Fla FV SW:FLGE_SALTY (P16322) (402 aa) fasta scores: E(): 4e-24, 40.08% id in 479 aa, and to Escherichia coli flagellar hook protein FlgE or FlaK or Fla FV or B1076 SW:FLGE_ECOLI (P75937) (401 aa) fasta scores: E(): 1.8e-25, 40.08% id in 479 aa. (473 aa)
BP0337Putative exported protein (pseudogene); Pseudogen. The N-terminal region of this CDS is deleted relative to its orthologues in B. pertussis and B. bronchiseptica. Similar to the C-reminal regions of Rhizobium meliloti conserved hypothetical protein Sma0690 TR:AAK65024 (EMBL:AE007228) (466 aa) fasta scores: E(): 2.3e-08, 28.617% id in 311 aa, and to Escherichia coli hypothetical protein YacH or B0117 SW:YACH_ECOLI (P36682) (617 aa) fasta scores: E(): 8.7e-11, 30.357% id in 280 aa. (276 aa)
ycgRConserved hypothetical protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility. (238 aa)
motASimilar to Escherichia coli chemotaxis MotA protein MotA or B1890 SW:MOTA_ECOLI (P09348) (295 aa) fasta scores: E(): 2.9e-60, 55.439% id in 285 aa, and to Salmonella typhimurium chemotaxis MotA protein MotA SW:MOTA_SALTY (P55891) (295 aa) fasta scores: E(): 9e-63, 56.842% id in 285 aa. (291 aa)
motBSimilar to Escherichia coli chemotaxis MotB protein MotB or B1889 or Z2943 or Ecs2599 SW:MOTB_ECOLI (P09349) (308 aa) fasta scores: E(): 8.5e-54, 57.500% id in 280 aa, and to Salmonella typhimurium chemotaxis MotB protein MotB SW:MOTB_SALTY (P55892) (309 aa) fasta scores: E(): 9.8e-54, 58.156% id in 282 aa. (315 aa)
cheZChemotaxis protein CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). (210 aa)
flgBFlagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body. (135 aa)
flgCSimilar to Salmonella typhimurium flagellar basal-body rod protein FlgC or FlaW or Fla FIII SW:FLGC_SALTY (P16438) (134 aa) fasta scores: E(): 3.4e-31, 67.39% id in 138 aa, and to Yersinia enterocolitica flagellar basal-body rod protein FlgC SW:FLGC_YEREN (Q56894) (134 aa) fasta scores: E(): 4.1e-32, 72.46% id in 138 aa. (139 aa)
flgFSimilar to Salmonella typhimurium flagellar basal-body rod protein FlgF or FlaX or Fla FVI SW:FLGF_SALTY (P16323) (251 aa) fasta scores: E(): 3.1e-34, 48.01% id in 252 aa, and to Escherichia coli flagellar basal-body rod protein FlgF or FlaX or Fla FVI or B1077 SW:FLGF_ECOLI (P75938) (251 aa) fasta scores: E(): 6.6e-34, 48.01% id in 252 aa. (254 aa)
flgGSimilar to Salmonella typhimurium flagellar basal-body rod protein FlgG or FlaL or Fla FVII SW:FLGG_SALTY (P16439) (260 aa) fasta scores: E(): 3.2e-60, 67.05% id in 261 aa, and to Escherichia coli, and flagellar basal-body rod protein FlgG or FlaL or Fla FVII or B1078 or Z1716 or Ecs1456 SW:FLGG_ECOLI (P75939) (260 aa) fasta scores: E(): 7.2e-60, 66.66% id in 261 aa. (261 aa)
flgHFlagellar L-ring protein precursor; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (229 aa)
flgIFlagellar P-ring protein precursor; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (377 aa)
flgLFlagellar hook-associated protein 3; Similar, over the N-terminal region, to Salmonella typhimurium flagellar hook-associated protein 3 FlgL or FlaT or FlaU SW:FLGL_SALTY (P16326) (317 aa) fasta scores: E(): 1.9e-21, 42.78% id in 194 aa, and to Pseudomonas aeruginosa flagellar hook-associated protein type 3 FlgL TR:Q9AGJ3 (EMBL:AF332547) (433 aa) fasta scores: E(): 2.4e-17, 28.29% id in 509 aa. (510 aa)
fliNSimilar to Escherichia coli flagellar motor switch protein FliN or MotD or FlaN or B1946 SW:FLIN_ECOLI (P15070) (137 aa) fasta scores: E(): 1.3e-23, 61.53% id in 130 aa, and to Salmonella typhimurium flagellar motor switch protein FliN or MotD or FlaNf SW:FLIN_SALTY (P26419) (137 aa) fasta scores: E(): 3.7e-24, 63.84% id in 130 aa. (166 aa)
fliMSimilar to Escherichia coli flagellar motor switch protein FliM or Fla AII or Fla QII or CheC2 or B1945 SW:FLIM_ECOLI (P06974) (334 aa) fasta scores: E(): 3.6e-66, 52.32% id in 323 aa, and to Salmonella typhimurium flagellar motor switch protein FliM or Fla AII or Fla QII or CheC2 SW:FLIM_SALTY (P26418) (334 aa) fasta scores: E(): 1.6e-67, 52.96% id in 321 aa. (336 aa)
fliLFlagellar protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. (182 aa)
fliJFlagellar protein FliJ; Similar to Escherichia coli flagellar protein FliJ or FlaO or FlaS or B1942 SW:FLIJ_ECOLI (P52613) (147 aa) fasta scores: E(): 5.2e-10, 33.1% id in 145 aa, and to Salmonella typhimurium flagellar protein FliJ or FlaO or FlaS SW:FLIJ_SALTY (P26463) (147 aa) fasta scores: E(): 6e-10, 33.79% id in 145 aa. (148 aa)
fliISimilar to Escherichia coli flagellum-specific ATP synthase FliI or Fla AIII or FlaC or B1941 SW:FLII_ECOLI (P52612) (457 aa) fasta scores: E(): 4.1e-87, 64.95% id in 468 aa, and to Salmonella typhimurium flagellum-specific ATP synthase FliI or Fla AIII or FlaC SW:FLII_SALTY (P26465) (456 aa) fasta scores: E(): 4.1e-87, 65.58% id in 462 aa. (477 aa)
fliHSimilar to Escherichia coli flagellar assembly protein FliH or Fla BIII or Fla AII.3 or B1940 SW:FLIH_ECOLI (P31068) (228 aa) fasta scores: E(): 4.8e-14, 29.77% id in 225 aa, and to Salmonella typhimurium flagellar assembly protein FliH or Fla BIII or Fla AII.3 SW:FLIH_SALTY (P15934) (235 aa) fasta scores: E(): 7.2e-15, 31.85% id in 226 aa. (251 aa)
fliGSimilar to Escherichia coli flagellar motor switch protein FliG or Fla BII or Fla AII.2 or b1939 or z3029 or ecs2678 SW:FLIG_ECOLI (P31067) (331 aa) fasta scores: E(): 1.7e-70, 61.39% id in 329 aa, and to Salmonella typhimurium flagellar motor switch protein FliG or Fla BII or Fla AII.2 SW:FLIG_SALTY (P15933) (331 aa) fasta scores: E(): 6.3e-70, 60.48% id in 329 aa. (336 aa)
fliFFlagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family. (558 aa)
fliESimilar to Escherichia coli flagellar hook-basal body complex protein FliE or FlaN or Fla AI or B1937 or Z3027 or Ecs2676 SW:FLIE_ECOLI (P25797) (103 aa) fasta scores: E(): 3e-12, 47.22% id in 108 aa, and to Salmonella typhimurium flagellar hook-basal body complex protein FliE or FlaN or Fla AI SW:FLIE_SALTY (P26462) (103 aa) fasta scores: E(): 1.9e-11, 45.79% id in 107 aa. (110 aa)
BP1405Hypothetical protein; No significant database matches. (131 aa)
bscQPutative type III secretion protein; Similar to Bordetella bronchiseptica BscQ TR:Q9L9E0 (EMBL:AF172245) (123 aa) fasta scores: E(): 3.4e-34, 98.9% id in 91 aa, and to Yersinia pestis Yop translocation protein Q SW:YSCQ_YERPE (P42713) (307 aa) fasta scores: E(): 7e-07, 46.37% id in 69 aa. (359 aa)
bscNPutative ATP synthase in type III secretion system; Similar to many eg. Bordetella bronchiseptica BscN TR:O68539 (EMBL:AF049488) (444 aa) fasta scores: E(): 2.6e-162, 99.32% id in 444 aa, and to Pseudomonas aeruginosa ATP synthase in type III secretion system pa1697 TR:Q9I330 (EMBL:AE004596) (440 aa) fasta scores: E(): 1.8e-103, 68.19% id in 415 aa. (444 aa)
marPossible membrane efflux protein; Similar to many proteins involved in multiple antibiotic resistance including: Salmonella typhimurium multiple antibiotic resistance protein MarC SW:MARC_SALTY (Q56068) (221 aa) fasta scores: E(): 6.2e-17, 29.68% id in 219 aa and to Escherichia coli multiple antibiotic resistance protein MarC SW:MARC_ECOLI (P31123) (221 aa) fasta scores: E(): 1.5e-16, 30.18% id in 222 aa. Previously sequenced as Bordetella pertussis putative multiple antibiotic resistance protein Mar TR:Q9X6A6 (EMBL:AF135154) (132 aa) fasta scores: E(): 1.2e-36, 100% id in 111 aa. Note [...] (219 aa)
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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