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BP1668 BP1668 wcbP wcbP BP1645 BP1645 BP1581 BP1581 BP1222 BP1222 BP1163 BP1163 phbB phbB BP1132 BP1132 fabI-2 fabI-2 BP3010 BP3010 BP3542 BP3542 BP0219 BP0219 BP0229 BP0229 BP3244 BP3244 BP2854 BP2854 BP2853 BP2853 BP2841 BP2841 BP2770 BP2770 BP2726 BP2726 idnO idnO FabG FabG FabG-2 FabG-2 BP0813 BP0813 fabG-5 fabG-5 BP2454 BP2454 fabG-4 fabG-4 BP2112 BP2112 BP2094 BP2094 BP1923 BP1923 fabG-3 fabG-3 BP1686 BP1686 FabG-3 FabG-3 fabI fabI BP1103 BP1103 fabG fabG fabG-2 fabG-2 BP1671 BP1671
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BP1668Similar to Pseudomonas aeruginosa probable short-chain dehydrogenase Pa5524 TR:Q9HT49 (EMBL:AE004965) (260 aa) fasta scores: E(): 1.6e-22, 38.43% id in 255 aa, and to Streptomyces cinnamonensis monensin polyketide synthase putative ketoacyl reductase SW:DHKR_STRCM (P41177) (261 aa) fasta scores: E(): 7.4e-21, 36.92% id in 260 aa. (257 aa)
wcbPPutative oxidoreductase; Similar to Myxococcus xanthus hypothetical oxidoreductase in uraA 5'region SW:YURA_MYXXA (P25970) (258 aa) fasta scores: E(): 1.4e-15, 39.35% id in 216 aa, and to Burkholderia mallei WcbP TR:Q9AI32 (EMBL:AF285636) (262 aa) fasta scores: E(): 2.1e-33, 44.26% id in 253 aa. (257 aa)
BP1645Probable short-chain dehydrogenase; Similar to Mycobacterium tuberculosis dehydrogenase Rv2857c or Mtv003.03C TR:O33339 (EMBL:AL008883) (258 aa) fasta scores: E(): 2.7e-28, 40.47% id in 252 aa, and to Rhizobium sp putative short-chain type dehydrogenase/reductase Y4lA SW:Y4LA_RHISN (P55541) (278 aa) fasta scores: E(): 5.9e-28, 36.86% id in 255 aa. (252 aa)
BP1581Similar to Streptomyces coelicolor putative oxidoreductase Scc75a.33 TR:Q9RKP1 (EMBL:AL133220) (263 aa) fasta scores: E(): 3.1e-58, 67.33% id in 248 aa, and to Rhizobium loti oxidoreductase Mll2989 TR:Q98H81 (EMBL:AP003000) (251 aa) fasta scores: E(): 2e-52, 57.49% id in 247 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa)
BP1222Probable short-chain dehydrogenase; Similar to Streptococcus agalactiae CylG TR:Q9X429 (EMBL:AF093787) (240 aa) fasta scores: E(): 1e-20, 34.16% id in 240 aa, and to Pseudomonas aeruginosa probable short-chain dehydrogenase Pa4162 TR:Q9HWL9 (EMBL:AE004832) (238 aa) fasta scores: E(): 2.6e-52, 61.53% id in 234 aa. (238 aa)
BP1163Similar to Picea abies short-chain type dehydrogenase/reductase SW:SDR1_PICAB (Q08632) (271 aa) fasta scores: E(): 1.4e-22, 38.37% id in 258 aa, and to Streptomyces coelicolor reductase Stah10.29 TR:Q9RKS8 (EMBL:AL132824) (262 aa) fasta scores: E(): 5e-40, 54.43% id in 248 aa. (259 aa)
phbBSimilar to Alcaligenes eutrophus acetoacetyl-CoA reductase PhbB SW:PHBB_ALCEU (P14697) (246 aa) fasta scores: E(): 1.6e-71, 76.82% id in 246 aa, and to Escherichia coli 3-oxoacyl-[acyl-carrier protein] reductase FabG or B1093 SW:FABG_ECOLI (P25716) (244 aa) fasta scores: E(): 2.5e-34, 45.67% id in 243 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)
BP1132Probable short-chain dehydrogenase; Similar to Vibrio harveyi 3-oxoacyl-[acyl-carrier protein] reductase FabG SW:FABG_VIBHA (P55336) (244 aa) fasta scores: E(): 6.5e-16, 40.85% id in 235 aa, and to Pseudomonas aeruginosa probable short-chain dehydrogenase Pa4162 TR:Q9HWL9 (EMBL:AE004832) (238 aa) fasta scores: E(): 4.7e-32, 47.8% id in 228 aa. (240 aa)
fabI-2Similar to Escherichia coli enoyl-[acyl-carrier-protein] reductase [NADH] FabI or EnvM or B1288 or Z2512 or ECS1861 SW:FABI_ECOLI (P29132) (261 aa) fasta scores: E(): 1.1e-60, 65.21% id in 253 aa. (261 aa)
BP3010Similar to Rhizobium meliloti putative oxidoreductase protein SMC01157 TR:CAC41799 (EMBL:AL591783) (259 aa) fasta scores: E(): 3e-26, 39.01% id in 264 aa. (270 aa)
BP3542Similar to Picea abies short-chain type dehydrogenase/reductase SW:SDR1_PICAB (Q08632) (271 aa) fasta scores: E(): 2.1e-15, 31.25% id in 240 aa, and to Pseudomonas aeruginosa probable short-chain dehydrogenase PA2918 TR:Q9HZS9 (EMBL:AE004718) (257 aa) fasta scores: E(): 1.8e-69, 82.57% id in 241 aa. (241 aa)
BP0219Similar to Pseudomonas aeruginosa probable short-chain dehydrogenase Pa4162 TR:Q9HWL9 (EMBL:AE004832) (238 aa) fasta scores: E(): 3.1e-29, 45.887% id in 231 aa, and to Streptomyces coelicolor putative short chain oxidoreductase 2 Scg61.28C TR:Q9K3Y7 (EMBL:AL359949) (253 aa) fasta scores: E(): 1.8e-20, 42.324% id in 241 aa. Similar to BP3244 (49.153% identity in 236 aa overlap) and to BP1222 (44.726% identity in 237 aa overlap. (241 aa)
BP0229Similar to Pseudomonas putida beta-D-hydroxybutyrate dehydrogenase BdhA TR:Q9AE70 (EMBL:AJ310211) (256 aa) fasta scores: E(): 1.6e-35, 45.349% id in 258 aa, and to Pseudomonas SpGM101 beta-hydroxybutyrate dehydrogenase HbdH TR:Q9KH52 (EMBL:AF271714) (255 aa) fasta scores: E(): 2.1e-35, 45.736% id in 258 aa. (265 aa)
BP3244Similar to Streptomyces galilaeus putative aklaviketone reductase AknU TR:Q9L4U4 (EMBL:AF264025) (267 aa) fasta scores: E(): 7.4e-22, 40.16% id in 244 aa, and to Streptomyces peucetius daunorubicin-doxorubicin polyketide synthase DnrH TR:Q54810 (EMBL:L35560) (251 aa) fasta scores: E(): 1.7e-19, 40.89% id in 247 aa. (236 aa)
BP2854Probable short chain dehydrogenase; Similar to Bacillus subtilis glucose 1-dehydrogenase ii ycdF SW:DHG2_BACSU (P80869) (258 aa) fasta scores: E(): 1.7e-26, 38.34% id in 253 aa. (249 aa)
BP2853Probable short chain dehydrogenase; Similar to several e.g. Streptomyces exfoliatus 20-beta-hydroxysteroid dehydrogenase SW:2BHD_STREX (P19992) (255 aa) fasta scores: E(): 1e-26, 41.4% id in 256 aa. (260 aa)
BP2841Similar to Pseudomonas aeruginosa probable short-chain dehydrogenase Pa0182 TR:Q9I6V0 (EMBL:AE004456) (250 aa) fasta scores: E(): 1.5e-43, 55.2% id in 250 aa and to Bacillus subtilis 3-oxoacyl-[acyl-carrier protein] reductase FabG SW:FABG_BACSU (P51831) (246 aa) fasta scores: E(): 7.9e-25, 37.86% id in 243 aa. (250 aa)
BP2770Probable short-chain dehydrogenase; Similar to many Prokaryotic and Eukaryotic dehydrogenases e.g. Pseudomonas aeruginosa probable short-chain dehydrogenase Pa2554 TR:Q9I0T0 (EMBL:AE004683) (255 aa) fasta scores: E(): 3.8e-60, 67.05% id in 255 aa and Drosophila melanogaster 3-hydroxyacyl-coa dehydrogenase type II Scu or Cg7113 SW:HCD2_DROME (O18404) (255 aa) fasta scores: E(): 6.6e-45, 55.9% id in 254 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)
BP2726Putative oxidoreductase; Similar to many inculding several proposed Prokaryotic and Eukaryotic acyl carrier proteins: Rhizobium loti 3-oxoacyl-acyl carrier protein reductase Mll1830 TR:Q98JQ5 (EMBL:AP002998) (234 aa) fasta scores: E(): 6.3e-55, 64.53% id in 234 aa and Cuphea lanceolata 3-oxoacyl-[acyl-carrier protein] reductase, chloroplast precursor Clkr27 SW:FABG_CUPLA (P28643) (320 aa) fasta scores: E(): 1.1e-17, 32.52% id in 246 aa 72.22% id in 234 aa. (234 aa)
idnOSimilar to Escherichia coli gluconate 5-dehydrogenase IdnO or B4266 SW:IDNO_ECOLI (P39345) (254 aa) fasta scores: E(): 1.8e-29, 40.000% id in 250 aa, and to Agrobacterium tumefaciens Agr_c_4386p TR:AAK88153 (EMBL:AE008155) (256 aa) fasta scores: E(): 1e-45, 54.545% id in 253 aa. (259 aa)
FabGAlcohol dehydrogenase; Similar to Escherichia coli 7-alpha-hydroxysteroid dehydrogenase HdhA or HsdH or B1619 or Z2624 or Ecs2327 SW:HDHA_ECOLI (P25529) (255 aa) fasta scores: E(): 7.5e-24, 37.751% id in 249 aa, and to Pseudomonas paucimobilis 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinX SW:LINX_PSEPA (P50198) (250 aa) fasta scores: E(): 9.2e-27, 40.873% id in 252 aa. (252 aa)
FabG-2Similar to Zoogloea ramigera acetoacetyl-CoA reductase PhbB SW:PHBB_ZOORA (P23238) (241 aa) fasta scores: E(): 2.3e-25, 38.710% id in 248 aa, and to Azospirillum brasilense nodulation protein G NodG SW:NODG_AZOBR (P17611) (246 aa) fasta scores: E(): 8.7e-26, 35.458% id in 251 aa. (250 aa)
BP0813Similar to Rhizobium loti probable short-chain dehydrogenase/reductase Mlr0808 TR:Q98LZ5 (EMBL:AP002995) (259 aa) fasta scores: E(): 1.2e-30, 45.985% id in 274 aa, and to Rhizobium meliloti putative oxidoreductase protein Smc01157 TR:CAC41799 (EMBL:AL591783) (259 aa) fasta scores: E(): 2.3e-21, 41.791% id in 268 aa. (274 aa)
fabG-5Similar to Escherichia coli 3-oxoacyl-[acyl-carrier protein] reductase FabG or B1093 SW:FABG_ECOLI (P25716) (244 aa) fasta scores: E(): 3.5e-29, 41.597% id in 238 aa. (248 aa)
BP2454Putative oxidoreductase; Similar to Alcaligenes eutrophus D-beta-hydroxybutyrate dehydrogenase HbdH1 SW:BDHA_ALCEU (Q9X6U2) (258 aa) fasta scores: E(): 7.9e-57, 63.84% id in 260 aa and to Rhizobium meliloti D-beta-hydroxybutyrate dehydrogenase BdhA or Rb1136 or Smb21010 SW:BDHA_RHIME (O86034) (258 aa) fasta scores: E(): 1e-45, 54.29% id in 256 aa. (260 aa)
fabG-43-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (250 aa)
BP2112Putative oxidoreductase; The methionine start codon of this CDS is substituted with a threonine. Similar to Escherichia coli oxidoreductase UcpA or B2426 SWALL:UCPA_ECOLI (SWALL:P37440) (263 aa) fasta scores: E(): 3.7e-23, 39.84% id in 256 aa, and to Rhizobium sp putative short-chain type dehydrogenase/reductase Y4lA SWALL:Y4LA_RHISN (SWALL:P55541) (278 aa) fasta scores: E(): 2.9e-25, 37.84% id in 251 aa. (262 aa)
BP2094Putative 3-oxoacyl-CoA or-ACP reductase; Similar to many e.g. Zoogloea ramigera acetoacetyl-CoA reductase phbB SW:PHBB_ZOORA (P23238) (241 aa) fasta scores: E(): 1.7e-24, 41.494% id in 241 aa and to Vibrio cholerae 3-oxoacyl-[acyl-carrier protein] reductase fabG or VC2021 SW:FABG_VIBCH (Q9KQH7) (244 aa) fasta scores: E(): 2.4e-23, 41.176% id in 238 aa. (240 aa)
BP1923Probable short chain dehydrogenase; Similar to Brevibacterium spHCU cyclohexanol dehydrogenase ChnA TR:AAK73164 (EMBL:AF257214) (256 aa) fasta scores: E(): 8.4e-30, 42.29% id in 253 aa, and to Streptomyces coelicolor probable oxidoreductase Scf41.15 TR:Q9RJV4 (EMBL:AL117387) (263 aa) fasta scores: E(): 2.4e-31, 45.23% id in 252 aa. (255 aa)
fabG-3Similar to Escherichia coli 3-oxoacyl-[acyl-carrier protein] reductase FabG or B1093 SW:FABG_ECOLI (P25716) (244 aa) fasta scores: E(): 3.3e-24, 36.69% id in 248 aa, and to Thermotoga maritima 3-oxoacyl-[acyl-carrier protein] reductase FabG or Tm1724 SW:FABG_THEMA (Q9X248) (246 aa) fasta scores: E(): 2.2e-27, 41.5% id in 253 aa. (258 aa)
BP1686Probable short-chain dehydrogenase; Similar to Pseudomonas abietaniphila DitG TR:Q9X4X1 (EMBL:AF119621) (244 aa) fasta scores: E(): 1.9e-35, 50.22% id in 227 aa, and to Rhizobium loti short-chain dehydrogenase/reductase family mlr5208 TR:Q98CC5 (EMBL:AP003006) (235 aa) fasta scores: E(): 7.2e-19, 37.11% id in 229 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (237 aa)
FabG-3Short-chain dehydrogenase; Similar to Escherichia coli 7-alpha-hydroxysteroid dehydrogenase HdhA or HsdH or B1619 or X2624 or Ecs2327 SW:HDHA_ECOLI (P25529) (255 aa) fasta scores: E(): 4.6e-23, 36.800% id in 250 aa, and to Rhodopseudomonas palustris putative 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase BadH TR:O07457 (EMBL:U75363) (255 aa) fasta scores: E(): 3.9e-27, 41.569% id in 255 aa. (258 aa)
fabISimilar to Escherichia coli, and enoyl-[acyl-carrier-protein] reductase [NADH] FabI or EnvM or B1288 or Z2512 or Ecs1861 SW:FABI_ECOLI (P29132) (261 aa) fasta scores: E(): 1.1e-35, 41.200% id in 250 aa, and to Rhizobium meliloti putative enoyl-acyl-carrier-protein reductase NADH TR:CAC41683 (EMBL:AL591783) (268 aa) fasta scores: E(): 3e-40, 44.578% id in 249 aa. (257 aa)
BP1103Probable short chain dehydrogenase; Similar to Homo sapiens sepiapterin reductase Spr SW:SPRE_HUMAN (P35270) (261 aa) fasta scores: E(): 2.1e-15, 38.4% id in 250 aa, and to Bacillus subtilis YueD protein TR:O32099 (EMBL:Z99120) (243 aa) fasta scores: E(): 1.1e-20, 36.25% id in 251 aa. (251 aa)
fabGSimilar to Escherichia coli 3-oxoacyl-[acyl-carrier protein] reductase FabG or B1093 SW:FABG_ECOLI (P25716) (244 aa) fasta scores: E(): 6e-23, 38.73% id in 253 aa, and to Pseudomonas aeruginosa 3-oxoacyl-[acyl-carrier protein] reductase FabG or Pa2967 SW:FABG_PSEAE (O54438) (247 aa) fasta scores: E(): 5.2e-25, 40.07% id in 252 aa. (252 aa)
fabG-2Similar to Escherichia coli 3-oxoacyl-[acyl-carrier protein] reductase FabG or B1093 SW:FABG_ECOLI (P25716) (244 aa) fasta scores: E(): 7.6e-21, 34.69% id in 245 aa, and to Agrobacterium tumefaciens Agr_l_2601p agr_l_2601 TR:AAK89866 (EMBL:AE008330) (246 aa) fasta scores: E(): 7.2e-29, 44.13% id in 247 aa. (251 aa)
BP1671Probable short chain dehydrogenase; Similar to Escherichia coli 3-oxoacyl-[acyl-carrier protein] reductase FabG or B1093 SW:FABG_ECOLI (P25716) (244 aa) fasta scores: E(): 1.2e-07, 27.23% id in 246 aa, and to Streptomyces coelicolor putative dehydrogenase/reductase Scah10.14C TR:Q9RKU3 (EMBL:AL132824) (258 aa) fasta scores: E(): 9.6e-08, 31.14% id in 244 aa. (229 aa)
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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