STRINGSTRING
ftsK ftsK amiC amiC mtgA mtgA mreB mreB gmK gmK lep lep ftsZ ftsZ ftsA ftsA ftsQ ftsQ ftsW ftsW ftsI ftsI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ftsKPutative cell division protein; Similar to many including: Burkholderia solanacearum probable cell division transmembrane protein FtsK TR:CAD16048 (EMBL:AL646069) (781 aa) fasta scores: E(): 1.1e-166, 66.62% id in 785 aa, and to Coxiella burnetii cell division protein FtsK SW:FTSK_COXBU (P39920) (778 aa) fasta scores: E(): 3.8e-125, 47.78% id in 766 aa. Also similar to the C-terminal of Escherichia coli cell division protein Ftsk or b0890 SW:FTSK_ECOLI (P46889) (1329 aa) fasta scores: E(): 5.4e-111, 60.81% id in 541 aa. (789 aa)
amiCSimilar to Escherichia coli N-acetylmuramoyl-L-alanine amidase AmiC precursor or B2817 SW:AMIC_ECOLI (Q46929) (417 aa) fasta scores: E(): 8.8e-41, 50.608% id in 411 aa, and to Pseudomonas aeruginosa N-acetylmuramoyl-L-alanine amidase AmiA or Pa5538 TR:Q9HT36 (EMBL:AE004966) (397 aa) fasta scores: E(): 1e-33, 41.667% id in 408 aa. (414 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (223 aa)
mreBSimilar to Escherichia coli rod shape-determining protein MreB or EnvB or RodY or B3251 SW:MREB_ECOLI (P13519) (347 aa) fasta scores: E(): 2.6e-88, 72.595% id in 343 aa, and to Vibrio cholerae MreB or Vc0415 TR:Q9ZA92 (EMBL:AF079234) (347 aa) fasta scores: E(): 2.6e-91, 74.487% id in 341 aa. (347 aa)
gmKGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (210 aa)
lepSignal peptidase I; Previously sequenced Bordetella pertussis leader peptidase Lep TR:Q9RN42 (EMBL:AF188620) (294 aa) fasta scores: E(): 1.9e-121, 100% id in 294 aa. Highly similar to Escherichia coli signal peptidase I LepB or b2568 SW:LEP_ECOLI (P00803) (324 aa) fasta scores: E(): 3.7e-22, 41.81% id in 342 aa, and to; Belongs to the peptidase S26 family. (294 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (394 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (408 aa)
ftsQPutative cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (273 aa)
ftsWCell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (397 aa)
ftsIPeptidoglycan synthetase precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (576 aa)
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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