STRINGSTRING
BP3596 BP3596 bfeA bfeA tonB tonB bvgS bvgS bfrE bfrE bfrD bfrD bvgA bvgA fauA fauA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BP3596Periplasmic binding protein; Similar to Salmonella typhimurium cobalamin periplasmic binding protein BtuF TR:Q9ZFP9 (EMBL:AF096877) (266 aa) fasta scores: E(): 2.9e-15, 34.66% id in 251 aa, and to Vibrio cholerae hypothetical protein VC2381 TR:Q9KPI6 (EMBL:AE004308) (276 aa) fasta scores: E(): 4e-24, 38.82% id in 255 aa. (297 aa)
bfeAFerric enterobactin receptor; Previously sequenced as Bordetella pertussis ferric enterobactin receptor BfeA TR:Q45341 (EMBL:U13950) (735 aa) fasta scores: E(): 0, 99.72% id in 737 aa. (737 aa)
tonBSiderophore-mediated iron transport protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (266 aa)
bvgSVirulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals. (1238 aa)
bfrEProbable TonB-dependent receptor for iron transport; Similar to Pseudomonas aeruginosa hydroxamate-type ferrisiderophore receptor PiuA or Fiu or Pa4514 TR:O68590 (EMBL:AF051690) (753 aa) fasta scores: E(): 3.4e-106, 43.742% id in 775 aa, and to Escherichia coli probable TonB-dependent receptor YbiL precursor YbiL or B0805 SW:YBIL_ECOLI (P75780) (760 aa) fasta scores: E(): 7.2e-50, 35.058% id in 773 aa. (752 aa)
bfrDProbable TonB-dependent receptor for iron transport; Probably involved in iron transport; Belongs to the TonB-dependent receptor family. (743 aa)
bvgAVirulence factors transcription regulator; Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes. (209 aa)
fauAPreviously sequenced Bordetella pertussis ferric alcaligin siderophore receptor FauA TR:Q9X6A5 (EMBL:AF135154) (734 aa) fasta scores: E(): 0, 100% id in 734 aa. (734 aa)
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.