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bscN bscN fliS fliS bopD bopD bscE bscE bscF bscF recA recA flgB flgB prn prn cheZ cheZ cheB cheB cheW cheW flaA flaA ldh ldh bopB bopB fim3 fim3 bvgS bvgS flgH flgH bvgA bvgA fhaB fhaB fimB fimB fimC fimC fhaC fhaC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bscNPutative ATP synthase in type III secretion system; Similar to many eg. Bordetella bronchiseptica BscN TR:O68539 (EMBL:AF049488) (444 aa) fasta scores: E(): 2.6e-162, 99.32% id in 444 aa, and to Pseudomonas aeruginosa ATP synthase in type III secretion system pa1697 TR:Q9I330 (EMBL:AE004596) (440 aa) fasta scores: E(): 1.8e-103, 68.19% id in 415 aa. (444 aa)
fliSFlagellar protein FliS; Similar to Salmonella typhimurium flagellar protein FliS SW:FLIS_SALTY (P26609) (135 aa) fasta scores: E(): 4.5e-19, 47.86% id in 117 aa, and to Escherichia coli flagellar protein FliS or B1925 SW:FLIS_ECOLI (P26608) (136 aa) fasta scores: E(): 1.8e-11, 33.33% id in 123 aa. (142 aa)
bopDSimilar to Bordetella bronchiseptica outer protein D BopD TR:Q9REZ6 (EMBL:AF207788) (313 aa) fasta scores: E(): 3.5e-86, 98.4% id in 313 aa. (313 aa)
bscEHypothetical protein; No significant database matches. (99 aa)
bscFSimilar to Pseudomonas aeruginosa putative type III secretion protein PscF or pa1719 TR:P95434 (EMBL:U56077) (85 aa) fasta scores: E(): 0.013, 27.9% id in 86 aa. (88 aa)
recARecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (353 aa)
flgBFlagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body. (135 aa)
prnPertactin precursor; Agglutinogen that binds to eukaryotic cells; a process mediated by the R-G-D sequence. Pertactin may have a role in bacterial adhesion, and thus play a role in virulence. May contribute to the disease state of whooping cough. (910 aa)
cheZChemotaxis protein CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). (210 aa)
cheBChemotaxis protein methyltransferase (Pseudogene); Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (350 aa)
cheWSimilar to Escherichia coli chemotaxis protein CheW or B1887 or Z2941 or Ecs2597 SW:CHEW_ECOLI (P07365) (167 aa) fasta scores: E(): 1.3e-41, 74.83% id in 155 aa, and to Burkholderia pseudomallei (Pseudomonas pseudomallei) chemotaxis protein CheW TR:O05183 (EMBL:U92493) (175 aa) fasta scores: E(): 7e-43, 72.56% id in 164 aa. (166 aa)
flaAFlagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (391 aa)
ldhSimilar to Alcaligenes eutrophus L-lactate dehydrogenase Ldh SW:LDH_ALCEU (Q07251) (349 aa) fasta scores: E(): 1.4e-89, 66.097% id in 351 aa, and to Escherichia coli hypothetical 38.9 kDa protein in dinG-glnQ intergenic region YbiC or B0801 SW:YBIC_ECOLI (P30178) (361 aa) fasta scores: E(): 5.4e-36, 35.277% id in 343 aa; Belongs to the LDH2/MDH2 oxidoreductase family. (351 aa)
bopBSimilar to Bordetella bronchiseptica outer protein B BopB TR:Q9REZ5 (EMBL:AF207789) (400 aa) fasta scores: E(): 2e-118, 96.75% id in 400 aa. (402 aa)
fim3Serotype 3 fimbrial subunit precursor; Bordetella pertussis is the causative agent of whooping cough. An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resist normal host-clearance mechanisms. It is unclear which bacterial cell surface component are responsible for adherence but the fimbriae of B.pertussis are prime candidates for being involved in this process; Belongs to the fimbrial protein family. (204 aa)
bvgSVirulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals. (1238 aa)
flgHFlagellar L-ring protein precursor; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (229 aa)
bvgAVirulence factors transcription regulator; Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes. (209 aa)
fhaBFilamentous hemagglutinin/adhesin; Evidence for a role in host-cell binding and infection. (3590 aa)
fimBFimbrial protein (pseudogene); Required for the biogenesis of the filamentous hemagglutinin and the fimbria; Belongs to the periplasmic pilus chaperone family. (244 aa)
fimCOuter membrane usher protein precursor; Probable porin-like protein necessary for the assembly of a pilin-type protein; Belongs to the fimbrial export usher family. (873 aa)
fhaCHemolysin activator-like protein; Member of a two partner secretion pathway (TPS) in which it mediates the secretion of filamentous hemagglutinin FHA (fhaB). Belongs to the TPS (TC 1.B.20) family. (584 aa)
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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