STRINGSTRING
ftsZ ftsZ SlmA SlmA trxA trxA lexA lexA recA recA ftsA ftsA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (394 aa)
SlmAPutative TetR-family transcriptional regulator; Similar to Escherichia coli Ttk protein or B3641 SW:TTK_ECOLI (P06969) (198 aa) fasta scores: E(): 1.6e-19, 44.693% id in 179 aa, and to Vibrio cholerae transcriptional regulator, TetR family vc0214 TR:Q9KVD2 (EMBL:AE004111) (210 aa) fasta scores: E(): 1.9e-24, 48.148% id in 189 aa. (191 aa)
trxAThioredoxin 1; Similar to Escherichia coli thioredoxin 1 TrxA or TsnC or FipA or B3781 SW:THIO_ECOLI (P00274) (108 aa) fasta scores: E(): 6.4e-28, 66.35% id in 107 aa, and to Pseudomonas aeruginosa thioredoxin TrxA or Trx or Pa5240 SW:THIO_PSEAE (Q9X2T1) (108 aa) fasta scores: E(): 7.2e-32, 75.92% id in 108 aa. Also similar to BP1713, 39.000% identity in 100 aa overlap. (141 aa)
lexALexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (216 aa)
recARecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (353 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (408 aa)
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
Server load: low (28%) [HD]