6 items (Bordetella pertussis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ompR	Hypothetical protein (Pseudogene); Pseudogene. This CDS is disrupted by the insertion of IS481 element. No significant database matches. (233 aa)
	fur	Ferric ion uptake regulator; Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. (139 aa)
	bvgA	Virulence factors transcription regulator; Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes. (209 aa)
	bvgS	Virulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals. (1238 aa)
	cheA	Chemotaxis protein CheY (Pseudogene); HMMPfam hit to PF00072, Response regulator receiver domain. (685 aa)
	risA	Sensor kinase protein (pseudogene); (C)3 in pertussis; (C)2 in parapertussis and bronchiseptica. (244 aa)

Your Current Organism:

Bordetella pertussis

NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
bvgA	bvgS	BP1878	BP1877	Virulence factors transcription regulator; Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes.	Virulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.	0.999
bvgA	ompR	BP1878	BP3222	Virulence factors transcription regulator; Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes.	Hypothetical protein (Pseudogene); Pseudogene. This CDS is disrupted by the insertion of IS481 element. No significant database matches.	0.575
bvgA	risA	BP1878	BP3554	Virulence factors transcription regulator; Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes.	Sensor kinase protein (pseudogene); (C)3 in pertussis; (C)2 in parapertussis and bronchiseptica.	0.573
bvgS	bvgA	BP1877	BP1878	Virulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.	Virulence factors transcription regulator; Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes.	0.999
bvgS	cheA	BP1877	BP1028	Virulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.	Chemotaxis protein CheY (Pseudogene); HMMPfam hit to PF00072, Response regulator receiver domain.	0.989
bvgS	fur	BP1877	BP2507	Virulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.	Ferric ion uptake regulator; Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.	0.461
bvgS	ompR	BP1877	BP3222	Virulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.	Hypothetical protein (Pseudogene); Pseudogene. This CDS is disrupted by the insertion of IS481 element. No significant database matches.	0.973
bvgS	risA	BP1877	BP3554	Virulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.	Sensor kinase protein (pseudogene); (C)3 in pertussis; (C)2 in parapertussis and bronchiseptica.	0.952
cheA	bvgS	BP1028	BP1877	Chemotaxis protein CheY (Pseudogene); HMMPfam hit to PF00072, Response regulator receiver domain.	Virulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.	0.989
cheA	ompR	BP1028	BP3222	Chemotaxis protein CheY (Pseudogene); HMMPfam hit to PF00072, Response regulator receiver domain.	Hypothetical protein (Pseudogene); Pseudogene. This CDS is disrupted by the insertion of IS481 element. No significant database matches.	0.568
fur	bvgS	BP2507	BP1877	Ferric ion uptake regulator; Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.	Virulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.	0.461
ompR	bvgA	BP3222	BP1878	Hypothetical protein (Pseudogene); Pseudogene. This CDS is disrupted by the insertion of IS481 element. No significant database matches.	Virulence factors transcription regulator; Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes.	0.575
ompR	bvgS	BP3222	BP1877	Hypothetical protein (Pseudogene); Pseudogene. This CDS is disrupted by the insertion of IS481 element. No significant database matches.	Virulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.	0.973
ompR	cheA	BP3222	BP1028	Hypothetical protein (Pseudogene); Pseudogene. This CDS is disrupted by the insertion of IS481 element. No significant database matches.	Chemotaxis protein CheY (Pseudogene); HMMPfam hit to PF00072, Response regulator receiver domain.	0.568
risA	bvgA	BP3554	BP1878	Sensor kinase protein (pseudogene); (C)3 in pertussis; (C)2 in parapertussis and bronchiseptica.	Virulence factors transcription regulator; Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes.	0.573
risA	bvgS	BP3554	BP1877	Sensor kinase protein (pseudogene); (C)3 in pertussis; (C)2 in parapertussis and bronchiseptica.	Virulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.	0.952